MUC1 and the immunobiology of cancer (Q35015673)

5 August 2017

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title

MUC1 and the immunobiology of cancer (English)

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5 August 2017

Joyce Taylor-Papadimitriou

1

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5 August 2017

Joy M Burchell

2

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5 August 2017

Timothy Plunkett

3

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5 August 2017

Rosalind Graham

4

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5 August 2017

Isabel Correa

5

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5 August 2017

David Miles

6

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5 August 2017

Michael Smith

7

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5 August 2017

1 April 2002

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Journal of Mammary Gland Biology and Neoplasia

5 August 2017

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5 August 2017

7

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5 August 2017

209-221

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5 August 2017

2

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https://scigraph.springernature.com/pub.10.1023/a:1020360121451

5 August 2017

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cites work

Genomic organization and structure of the 3' region of human MUC3: alternative splicing predicts membrane-bound and soluble forms of the mucin

1 reference

12 December 2020

Expression of B7.1 in a MUC1-expressing mouse mammary epithelial tumour cell line inhibits tumorigenicity but does not induce autoimmunity in MUC1 transgenic mice

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12 December 2020

Comparison of O-linked carbohydrate chains in MUC-1 mucin from normal breast epithelial cell lines and breast carcinoma cell lines. Demonstration of simpler and fewer glycan chains in tumor cells.

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12 December 2020

Episialin (MUC1) overexpression inhibits integrin-mediated cell adhesion to extracellular matrix components

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12 December 2020

Radioimmunotherapy for breast cancer using indium-111/yttrium-90 BrE-3: results of a phase I clinical trial

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12 December 2020

Detection of the tumour-associated antigens recognized by the monoclonal antibodies HMFG-1 and 2 in serum from patients with breast cancer

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12 December 2020

Structures of acidic O-linked polylactosaminoglycans on human skim milk mucins

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12 December 2020

Structures of neutral O-linked polylactosaminoglycans on human skim milk mucins. A novel type of linearly extended poly-N-acetyllactosamine backbones with Gal beta(1-4)GlcNAc beta(1-6) repeating units.

1 reference

12 December 2020

Multiple facets of sialomucin complex/MUC4, a membrane mucin and erbb2 ligand, in tumors and tissues (Y2K update).

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12 December 2020

Novel breast-tumor-associated MUC1-derived peptides: characterization in Db-/- x beta2 microglobulin (beta2m) null mice transgenic for a chimeric HLA-A2.1/Db-beta2 microglobulin single chain

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12 December 2020

Macrophage-tumour cell interactions: identification of MUC1 on breast cancer cells as a potential counter-receptor for the macrophage-restricted receptor, sialoadhesin

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12 December 2020

A transfected sialyltransferase that is elevated in breast cancer and localizes to the medial/trans-Golgi apparatus inhibits the development of core-2-based O-glycans

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12 December 2020

Polymorphic epithelial mucin (MUC-1)-containing circulating immune complexes in carcinoma patients

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12 December 2020

Specific, major histocompatibility complex-unrestricted recognition of tumor-associated mucins by human cytotoxic T cells

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12 December 2020

Recombinant vaccinia virus encoding human MUC1 and IL2 as immunotherapy in patients with breast cancer

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12 December 2020

Dendritic cells in cancer immunotherapy

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12 December 2020

Cloning of a human UDP-N-acetyl-alpha-D-Galactosamine:polypeptide N-acetylgalactosaminyltransferase that complements other GalNAc-transferases in complete O-glycosylation of the MUC1 tandem repeat

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12 December 2020

Cytotoxic T-lymphocytes derived from patients with breast adenocarcinoma recognize an epitope present on the protein core of a mucin molecule preferentially expressed by malignant cells

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12 December 2020

Reversal of tolerance to human MUC1 antigen in MUC1 transgenic mice immunized with fusions of dendritic and carcinoma cells

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12 December 2020

Differentiation antigens expressed by epithelial cells in the lactating breast are also detectable in breast cancers

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12 December 2020

Long term survival of patients with advanced ovarian cancer treated with intraperitoneal radioimmunotherapy

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12 December 2020

Humoral immune response to polymorphic epithelial mucin (MUC-1) in patients with benign and malignant breast tumours

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12 December 2020

A core protein epitope of the polymorphic epithelial mucin detected by the monoclonal antibody SM-3 is selectively exposed in a range of primary carcinomas

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12 December 2020

Expression of MUC1 mucin on activated human T cells: implications for a role of MUC1 in normal immune regulation

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12 December 2020

A family of UDP-GalNAc: polypeptide N-acetylgalactosaminyl-transferases control the initiation of mucin-type O-linked glycosylation.

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12 December 2020

An alpha2,3 sialyltransferase (ST3Gal I) is elevated in primary breast carcinomas

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12 December 2020

High density O-glycosylation on tandem repeat peptide from secretory MUC1 of T47D breast cancer cells

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12 December 2020

Therapy of human tumors in NOD/SCID mice with patient-derived reactivated memory T cells from bone marrow.

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12 December 2020

Substrate specificities of three members of the human UDP-N-acetyl-alpha-D-galactosamine:Polypeptide N-acetylgalactosaminyltransferase family, GalNAc-T1, -T2, and -T3

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12 December 2020

Identification of an HLA-A11-restricted epitope from the tandem repeat domain of the epithelial tumor antigen mucin

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12 December 2020

Expression of sialyl-Tn predicts the effect of adjuvant chemotherapy in node-positive breast cancer

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12 December 2020

Three different vaccines based on the 140-amino acid MUC1 peptide with seven tandemly repeated tumor-specific epitopes elicit distinct immune effector mechanisms in wild-type versus MUC1-transgenic mice with different potential for tumor rejection

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12 December 2020

The relative activities of the C2GnT1 and ST3Gal-I glycosyltransferases determine O-glycan structure and expression of a tumor-associated epitope on MUC1.

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12 December 2020

Mucin biosynthesis and macromolecular assembly

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12 December 2020

The polymorphic epithelial mucin: potential as an immunogen for a cancer vaccine

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12 December 2020

Tyrosine replacement in P-selectin glycoprotein ligand-1 affects distinct kinetic and mechanical properties of bonds with P- and L-selectin.

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12 December 2020

Decreased MUC1 expression induces E-cadherin-mediated cell adhesion of breast cancer cell lines

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12 December 2020

Radioimmunoscintigraphy in patients with ovarian cancer

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12 December 2020

The breast mucin MUCI as a novel adhesion ligand for endothelial intercellular adhesion molecule 1 in breast cancer

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12 December 2020

Effective immunotherapy of cancer in MUC1-transgenic mice using clonal cytotoxic T lymphocytes directed against an immunodominant MUC1 epitope.

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12 December 2020

Molecular cloning and expression of human tumor-associated polymorphic epithelial mucin

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12 December 2020

CA 15-3: a prognostic marker in breast cancer.

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12 December 2020

Identification of three non-VNTR MUC1-derived HLA-A*0201-restricted T-cell epitopes that induce protective anti-tumor immunity in HLA-A2/K(b)-transgenic mice

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12 December 2020

T-cell recognition of tumor-associated carbohydrates: the nature of the glycan moiety plays a decisive role in determining glycopeptide immunogenicity

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12 December 2020

Humoral immune response induced by the protein core of MUC1 mucin in pregnant and healthy women

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12 December 2020

Identification and topology of variant sequences within individual repeat domains of the human epithelial tumor mucin MUC1

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12 December 2020

99mTc-labelled SM3 in the preoperative evaluation of axillary lymph nodes and primary breast cancer with change detection statistical processing as an aid to tumour detection

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12 December 2020

A mechanism for inhibition of E-cadherin-mediated cell-cell adhesion by the membrane-associated mucin episialin/MUC1.

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12 December 2020

Report on the first international workshop on carcinoma-associated mucins

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12 December 2020

Identification of HLA-A2-restricted T-cell epitopes derived from the MUC1 tumor antigen for broadly applicable vaccine therapies

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12 December 2020

Development and characterization of breast cancer reactive monoclonal antibodies directed to the core protein of the human milk mucin.

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12 December 2020

Cloning and sequencing of a human pancreatic tumor mucin cDNA.

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12 December 2020

Rapid induction of primary human CD4+ and CD8+ T cell responses against cancer-associated MUC1 peptide epitopes

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12 December 2020

Lack of evidence for an immunosuppressive role for MUC1.

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12 December 2020

Localization of O-glycosylation sites on glycopeptide fragments from lactation-associated MUC1. All putative sites within the tandem repeat are glycosylation targets in vivo

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12 December 2020

Expression of the gene coding for a human mucin in mouse mammary tumor cells can affect their tumorigenicity

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12 December 2020

Intramuscular immunisation with MUC1 cDNA can protect C57 mice challenged with MUC1-expressing syngeneic mouse tumour cells

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12 December 2020

Characterization of human sialoadhesin, a sialic acid binding receptor expressed by resident and inflammatory macrophage populations

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12 December 2020

The epithelial mucin, MUC1, is expressed on resting T lymphocytes and can function as a negative regulator of T cell activation

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12 December 2020

Carbohydrate recognition on MUC1-expressing targets enhances cytotoxicity of a T cell subpopulation

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12 December 2020

Induction of antitumor immunity by vaccination of dendritic cells transfected with MUC1 RNA

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12 December 2020

Molecular cloning and analysis of the mouse homologue of the tumor-associated mucin, MUC1, reveals conservation of potential O-glycosylation sites, transmembrane, and cytoplasmic domains and a loss of minisatellite-like polymorphism

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12 December 2020

Intercellular and intracellular events following the MHC-unrestricted TCR recognition of a tumor-specific peptide epitope on the epithelial antigen MUC1

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12 December 2020

Specificity analysis of sera from breast cancer patients vaccinated with MUC1-KLH plus QS-21.

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12 December 2020

Mucins in airway secretions from healthy and chronic bronchitic subjects

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12 December 2020

Keyhole limpet hemocyanin conjugate vaccines against cancer: the Memorial Sloan Kettering experience

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12 December 2020

MUC1 gene polymorphism in the gastric carcinogenesis pathway.

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12 December 2020

Regression of human metastatic renal cell carcinoma after vaccination with tumor cell-dendritic cell hybrids

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12 December 2020

Siglecs, sialic acids and innate immunity

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12 December 2020

Overexpression of MUC1 reconfigures the binding properties of tumor cells

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12 December 2020

Reactivity of natural and induced human antibodies to MUC1 mucin with MUC1 peptides and n-acetylgalactosamine (GalNAc) peptides

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12 December 2020

A randomised phase II study of sialyl-Tn and DETOX-B adjuvant with or without cyclophosphamide pretreatment for the active specific immunotherapy of breast cancer

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12 December 2020

Comparison of sialyl-Lewis a-carrying CD43 and MUC1 mucins secreted from a colon carcinoma cell line for E-selectin binding and inhibition of leukocyte adhesion.

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12 December 2020

Presentation of MUC1 tumor antigen by class I MHC and CTL function correlate with the glycosylation state of the protein taken Up by dendritic cells

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12 December 2020

Oligosaccharide differences in the DF3 sialomucin antigen from normal human milk and the BT-20 human breast carcinoma cell line

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12 December 2020

MUC1 cross-reactive Galα(l,3)Gal antibodies in humans switch immune responses from cellular to humoral

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12 December 2020

Induction of cytotoxic T-lymphocyte responses in vivo after vaccinations with peptide-pulsed dendritic cells

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12 December 2020

Cancer-associated MUC1 mucin inhibits human T-cell proliferation, which is reversible by IL-2

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12 December 2020

Identifiers

DOI

10.1023/A:1020360121451

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Dimensions Publication ID

5 August 2017

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