The connexin 40 A96S mutation causes renin-dependent hypertension. (Q35012387)

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1 February 2020

title

The connexin 40 A96S mutation causes renin-dependent hypertension (English)

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5

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author name string

Indra Lübkemeier

1

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1 February 2020

Katharina Machura

2

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1 February 2020

Lisa Kurtz

3

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1 February 2020

Björn Neubauer

4

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1 February 2020

Frank Schweda

6

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1 February 2020

Charlotte Wagner

7

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1 February 2020

Klaus Willecke

8

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1 February 2020

Armin Kurtz

9

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publication date

19 May 2011

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Journal of the American Society of Nephrology

1 February 2020

published in

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volume

22

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issue

6

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page(s)

1031-1040

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Selective deletion of Connexin 40 in renin-producing cells impairs renal baroreceptor function and is associated with arterial hypertension.

1 February 2020

cites work

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3103723

Physiology of kidney renin

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3103723

Connexin expression in renin-producing cells

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3103723

Function of connexins in the renal circulation

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3103723

Connexin40 is essential for the pressure control of renin synthesis and secretion

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3103723

Somatic mutations in the connexin 40 gene (GJA5) in atrial fibrillation

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3103723

Cx40 and Cx43 expression ratio influences heteromeric/ heterotypic gap junction channel properties

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3103723

Gap junction channels formed by coexpressed connexin40 and connexin43

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3103723

High-efficiency deleter mice show that FLPe is an alternative to Cre-loxP

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3103723

Formation of heteromeric gap junction channels by connexins 40 and 43 in vascular smooth muscle cells

8 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3103723

Improved properties of FLP recombinase evolved by cycling mutagenesis.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3103723

An Fgf8 mutant allelic series generated by Cre- and Flp-mediated recombination

8 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3103723

Connexin40, a component of gap junctions in vascular endothelium, is restricted in its ability to interact with other connexins

8 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3103723

Specific permeability and selective formation of gap junction channels in connexin-transfected HeLa cells

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3103723

Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction

8 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3103723

A new mouse embryonic stem cell line with good germ line contribution and gene targeting frequency

8 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3103723

Loss of connexin40 is associated with decreased endothelium-dependent relaxations and eNOS levels in the mouse aorta.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3103723

Some oculodentodigital dysplasia-associated Cx43 mutations cause increased hemichannel activity in addition to deficient gap junction channels

25 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3103723

Endothelium-specific replacement of the connexin43 coding region by a lacZ reporter gene

25 October 2018

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12 December 2020

Immunochemical and electrophysiological characterization of murine connexin40 and -43 in mouse tissues and transfected human cells

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12 December 2020

Polymorphisms in human connexin40 gene promoter are associated with increased risk of hypertension in men

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12 December 2020

Lack of connexin 40 causes displacement of renin-producing cells from afferent arterioles to the extraglomerular mesangium

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12 December 2020

Connexin40 regulates renin production and blood pressure

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12 December 2020

High-level connexin expression in the human juxtaglomerular apparatus

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12 December 2020

Identifiers

DOI

10.1681/ASN.2010101047

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1 February 2020

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1 February 2020

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