A new-generation 5-nitroimidazole can induce highly metronidazole-resistant Giardia lamblia in vitro (Q35011418)

5 August 2017

A new-generation 5-nitroimidazole can induce highly metronidazole-resistant Giardia lamblia in vitro (English)

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5 August 2017

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Frances D Gillin

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5 August 2017

Jacqueline A. Upcroft

9

object named as

Jacqueline A Upcroft

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5 August 2017

8

Peter Upcroft

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5 August 2017

Linda A Dunn

1

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5 August 2017

Anita G Burgess

2

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5 August 2017

Kenia G Krauer

3

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5 August 2017

Lars Eckmann

4

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5 August 2017

Patrice Vanelle

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5 August 2017

Maxime D Crozet

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5 August 2017

24 April 2010

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International Journal of Antimicrobial Agents

5 August 2017

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5 August 2017

36

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5 August 2017

1

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5 August 2017

37-42

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Synthesis and electrochemistry of 2-ethenyl and 2-ethanyl derivatives of 5-nitroimidazole and antimicrobial activity against Giardia lamblia

5 August 2017

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3103471

Trichomonas vaginalis: metronidazole and other nitroimidazole drugs are reduced by the flavin enzyme thioredoxin reductase and disrupt the cellular redox system. Implications for nitroimidazole toxicity and resistance.

8 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3103471

Giardia, Entamoeba, and Trichomonas enzymes activate metronidazole (nitroreductases) and inactivate metronidazole (nitroimidazole reductases).

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3103471

New insights on classification, identification, and clinical relevance of Blastocystis spp.

8 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3103471

Nitroimidazole action in Entamoeba histolytica: a central role for thioredoxin reductase

8 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3103471

Efficacy of antigiardial drugs

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3103471

Drug resistance in the sexually transmitted protozoan Trichomonas vaginalis

8 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3103471

Mechanisms of in vitro development of resistance to metronidazole in Trichomonas vaginalis

8 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3103471

Methods for cultivation of luminal parasitic protists of clinical importance

8 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3103471

Drug susceptibility testing of anaerobic protozoa

8 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3103471

Drug targets and mechanisms of resistance in the anaerobic protozoa

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3103471

Inhibition of pyruvate-ferredoxin oxidoreductase gene expression in Giardia lamblia by a virus-mediated hammerhead ribozyme

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3103471

Efficacy of new 5-nitroimidazoles against metronidazole-susceptible and -resistant Giardia, Trichomonas, and Entamoeba spp

8 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3103471

Nitroimidazole drugs-action and resistance mechanisms I. Mechanism of action

8 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3103471

Altered uptake of metronidazole in vitro by stocks of Giardia intestinalis with different drug sensitivities.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3103471

Induction of metronidazole and furazolidone resistance in Giardia

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3103471

In vitro resistance to 5-nitroimidazoles and benzimidazoles in Giardia duodenalis: variability and variation in gene expression.

8 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3103471

Lowering of 5-nitroimidazole's mutagenicity: towards optimal antiparasitic pharmacophore.

25 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3103471

Characterization of Giardia lamblia WB C6 clones resistant to nitazoxanide and to metronidazole.

25 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3103471

5-Nitroimidazole drugs effective against metronidazole-resistant Trichomonas vaginalis and Giardia duodenalis

25 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3103471

Variability and variation in drug susceptibility among Giardia duodenalis isolates and clones exposed to 5-nitroimidazoles and benzimidazoles in vitro

25 October 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3103471

Molecular basis of metronidazole resistance in pathogenic bacteria and protozoa.

25 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3103471

Metronidazole and albendazole susceptibility of 11 clinical isolates of Giardia duodenalis from France.

25 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3103471

Albendazole resistance in Giardia is correlated with cytoskeletal changes but not with a mutation at amino acid 200 in beta-tubulin.

25 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3103471

A purified ferredoxin from Giardia duodenalis

25 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3103471

Quinacrine-resistant Giardia duodenalis

25 October 2018

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12 December 2020

Mode of action of metronidazole on anaerobic bacteria and protozoa

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12 December 2020

Biological and genetic analysis of a longitudinal collection of Giardia samples derived from humans

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12 December 2020

The sensitivity of Giardia intestinalis to drugs in vitro

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12 December 2020

Characterisation and purification of pyruvate:ferredoxin oxidoreductase from Giardia duodenalis

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12 December 2020

Ferredoxin involvement in metronidazole resistance of Giardia duodenalis

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12 December 2020

A comparison of the in-vitro activity of some 5-nitroimidazoles and other compounds against Giardia intestinalis

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12 December 2020

A H2O-producing NADH oxidase from the protozoan parasite Giardia duodenalis

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12 December 2020

Drug resistance in Giardia: clinical versus laboratory isolates

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12 December 2020

10.1016/J.IJANTIMICAG.2010.03.004

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DOI

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5 August 2017

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5 August 2017

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