Increased oxidative metabolism and neurotransmitter cycling in the brain of mice lacking the thyroid hormone transporter SLC16A2 (MCT8) (Q35008972)

5 August 2017

Increased oxidative metabolism and neurotransmitter cycling in the brain of mice lacking the thyroid hormone transporter SLC16A2 (MCT8) (English)

1 reference

5 August 2017

1 reference

Carmen Grijota-Martinez

Carmen Grijota-Martínez

3

0 references

Tiago B Rodrigues

Tiago B Rodrigues

1

0 references

Beatriz Morte

Beatriz Morte

7

0 references

Juan Bernal

Juan Bernal

8

0 references

author name string

Ainhoa Ceballos

2

1 reference

5 August 2017

Barbara Nuñez

4

1 reference

5 August 2017

Samuel Refetoff

5

1 reference

5 August 2017

Sebastian Cerdán

6

1 reference

5 August 2017

language of work or name

English

0 references

publication date

1 October 2013

1 reference

5 August 2017

1 reference

5 August 2017

8

1 reference

5 August 2017

e74621

1 reference

5 August 2017

10

1 reference

Creative Commons Attribution 4.0 International

5 August 2017

start time

1 October 2013

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

cites work

Changes in thyroid status during perinatal development of MCT8-deficient male mice

1 reference

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The pathophysiological consequences of thyroid hormone transporter deficiencies: Insights from mouse models

8 July 2018

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Critical role of types 2 and 3 deiodinases in the negative regulation of gene expression by T₃in the mouse cerebral cortex.

8 July 2018

1 reference

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Mice deficient in MCT8 reveal a mechanism regulating thyroid hormone secretion

8 July 2018

1 reference

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Essential molecular determinants for thyroid hormone transport and first structural implications for monocarboxylate transporter 8.

8 July 2018

1 reference

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Thyroid hormone-regulated mouse cerebral cortex genes are differentially dependent on the source of the hormone: a study in monocarboxylate transporter-8- and deiodinase-2-deficient mice.

8 July 2018

1 reference

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Molecular aspects of thyroid hormone actions

8 July 2018

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A thyroid hormone analog with reduced dependence on the monocarboxylate transporter 8 for tissue transport

8 July 2018

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Redox dependence and compartmentation of [13C]pyruvate in the brain of deuterated rats bearing implanted C6 gliomas.

8 July 2018

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Monocarboxylate transporter 8 in neuronal cell growth.

8 July 2018

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Expression of the thyroid hormone transporters monocarboxylate transporter-8 (SLC16A2) and organic ion transporter-14 (SLCO1C1) at the blood-brain barrier

8 July 2018

1 reference

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Novel biological and clinical aspects of thyroid hormone metabolism

8 July 2018

1 reference

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Thyroid hormone transporter defects

8 July 2018

1 reference

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The MCT8 thyroid hormone transporter and Allan-Herndon-Dudley syndrome

8 July 2018

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8 July 2018

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Abnormal thyroid hormone metabolism in mice lacking the monocarboxylate transporter 8

8 July 2018

1 reference

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Thyroid hormone receptors in brain development and function

8 July 2018

1 reference

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Mechanisms of disease: psychomotor retardation and high T3 levels caused by mutations in monocarboxylate transporter 8.

8 July 2018

1 reference

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The glutamate/GABA-glutamine cycle: aspects of transport, neurotransmitter homeostasis and ammonia transfer.

8 July 2018

1 reference

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X-linked MCT8 gene mutations: characterization of the pediatric neurologic phenotype

8 July 2018

1 reference

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A fast and sensitive 1H NMR method to measure the turnover of the H2 hydrogen of lactate.

8 July 2018

1 reference

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X-linked paroxysmal dyskinesia and severe global retardation caused by defective MCT8 gene

8 July 2018

1 reference

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Thyroid hormone transporters

8 July 2018

1 reference

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Futile cycling of lactate through the plasma membrane of C6 glioma cells as detected by (13C, 2H) NMR.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3788064

Association between mutations in a thyroid hormone transporter and severe X-linked psychomotor retardation

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3788064

A novel syndrome combining thyroid and neurological abnormalities is associated with mutations in a monocarboxylate transporter gene

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3788064

Identification of monocarboxylate transporter 8 as a specific thyroid hormone transporter

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3788064

Effects of maternal hypothyroidism on the weight and thyroid hormone content of rat embryonic tissues, before and after onset of fetal thyroid function.

8 July 2018

1 reference

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Neurological signs in congenital iodine-deficiency disorder (endemic cretinism).

8 July 2018

1 reference

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Changes in phosphofructokinase and pyruvate kinase in rat brain following thyroidectomy.

8 July 2018

1 reference

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Cerebral metabolism of [1,2-13C2]acetate as detected by in vivo and in vitro 13C NMR.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3788064

Extended clinical phenotype, endocrine investigations and functional studies of a loss-of-function mutation A150V in the thyroid hormone specific transporter MCT8.

8 July 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0074621

Clinical phenotype and endocrinological investigations in a patient with a mutation in the MCT8 thyroid hormone transporter.

21 January 2018

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https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0074621

1H magnetic resonance spectroscopy in monocarboxylate transporter 8 gene deficiency

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0074621

Neuronal 3',3,5-triiodothyronine (T3) uptake and behavioral phenotype of mice deficient in Mct8, the neuronal T3 transporter mutated in Allan-Herndon-Dudley syndrome.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0074621

Tissue-specific thyroid hormone deprivation and excess in monocarboxylate transporter (mct) 8-deficient mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0074621

Impact of Oatp1c1 deficiency on thyroid hormone metabolism and action in the mouse brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0074621

Quantitative membrane protein expression at the blood-brain barrier of adult and younger cynomolgus monkeys.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0074621

Thyroid hormone homeostasis and action in the type 2 deiodinase-deficient rodent brain during development.

21 January 2018

1 reference

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Impact of monocarboxylate transporter-8 deficiency on the hypothalamus-pituitary-thyroid axis in mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0074621

Hypothyroidism decreases the biogenesis in free mitochondria and neuronal oxygen consumption in the cerebral cortex of developing rats.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0074621

Thyroid hormone action in the adult brain: gene expression profiling of the effects of single and multiple doses of triiodo-L-thyronine in the rat striatum.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0074621

White matter abnormalities and dystonic motor disorder associated with mutations in the SLC16A2 gene

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3788064

Elevated serum triiodothyronine and intellectual and motor disability with paroxysmal dyskinesia caused by a monocarboxylate transporter 8 gene mutation

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3788064

Adult-onset hypothyroidism and the cerebral metabolism of (1,2-13C2) acetate as detected by 13C nuclear magnetic resonance

26 October 2018

1 reference

12 December 2020

Glucose and lactate metabolism in C6 glioma cells: evidence for the preferential utilization of lactate for cell oxidative metabolism

1 reference

12 December 2020

Transthyretin regulates thyroid hormone levels in the choroid plexus, but not in the brain parenchyma: study in a transthyretin-null mouse model

1 reference

12 December 2020

Compartmentation of lactate and glucose metabolism in C6 glioma cells. A 13c and 1H NMR study

1 reference

12 December 2020

Automatic recording apparatus for use in the chromatography of amino acids

1 reference

12 December 2020

10.1371/JOURNAL.PONE.0074621

Identifiers

DOI

1 reference

5 August 2017

0 references

1 reference

5 August 2017

1 reference