Sorafenib sensitizes solid tumors to Apo2L/TRAIL and Apo2L/TRAIL receptor agonist antibodies by the Jak2-Stat3-Mcl1 axis (Q35005616)

5 August 2017

Sorafenib sensitizes solid tumors to Apo2L/TRAIL and Apo2L/TRAIL receptor agonist antibodies by the Jak2-Stat3-Mcl1 axis (English)

1 reference

5 August 2017

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24086526%20AND%20SRC:MED&resulttype=core&format=json

31 May 2020

author name string

Junaid Abdulghani

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24086526%20AND%20SRC:MED&resulttype=core&format=json

31 May 2020

Joshua E Allen

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24086526%20AND%20SRC:MED&resulttype=core&format=json

31 May 2020

David T Dicker

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24086526%20AND%20SRC:MED&resulttype=core&format=json

31 May 2020

Yingqiu Yvette Liu

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24086526%20AND%20SRC:MED&resulttype=core&format=json

31 May 2020

David Goldenberg

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24086526%20AND%20SRC:MED&resulttype=core&format=json

31 May 2020

Charles D Smith

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24086526%20AND%20SRC:MED&resulttype=core&format=json

31 May 2020

Robin Humphreys

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24086526%20AND%20SRC:MED&resulttype=core&format=json

31 May 2020

language of work or name

English

0 references

publication date

26 September 2013

1 reference

5 August 2017

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24086526%20AND%20SRC:MED&resulttype=core&format=json

31 May 2020

volume

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24086526%20AND%20SRC:MED&resulttype=core&format=json

31 May 2020

issue

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24086526%20AND%20SRC:MED&resulttype=core&format=json

31 May 2020

page(s)

e75414

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24086526%20AND%20SRC:MED&resulttype=core&format=json

Creative Commons Attribution 4.0 International

31 May 2020

copyright license

start time

26 September 2013

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

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8 July 2018

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Enhanced metastasis suppression by targeting TRAIL receptor 2 in a murine model of triple-negative breast cancer

8 July 2018

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8 July 2018

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Predominant antitumor effects by fully human anti-TRAIL-receptor 2 (DR5) monoclonal antibodies in human glioma cells in vitro and in vivo

8 July 2018

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Drug combination studies and their synergy quantification using the Chou-Talalay method

8 July 2018

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Phase I and pharmacokinetic study of lexatumumab (HGS-ETR2) given every 2 weeks in patients with advanced solid tumors

8 July 2018

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8 July 2018

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8 July 2018

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Stat3 promotes metastatic progression of prostate cancer.

8 July 2018

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Beta-sitosterol sensitizes MDA-MB-231 cells to TRAIL-induced apoptosis

8 July 2018

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Phase 2 study of mapatumumab, a fully human agonistic monoclonal antibody which targets and activates the TRAIL receptor-1, in patients with advanced non-small cell lung cancer

8 July 2018

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MicroRNA signatures of TRAIL resistance in human non-small cell lung cancer

8 July 2018

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Reduction of TRAIL-induced Mcl-1 and cIAP2 by c-Myc or sorafenib sensitizes resistant human cancer cells to TRAIL-induced death.

8 July 2018

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Clearing the TRAIL for Cancer Therapy

8 July 2018

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Stat3 is tyrosine-phosphorylated through the interleukin-6/glycoprotein 130/Janus kinase pathway in breast cancer.

8 July 2018

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Sorafenib for the treatment of advanced renal cell carcinoma

8 July 2018

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Sorafenib blocks the RAF/MEK/ERK pathway, inhibits tumor angiogenesis, and induces tumor cell apoptosis in hepatocellular carcinoma model PLC/PRF/5.

8 July 2018

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Mcl-1 overexpression in hepatocellular carcinoma: a potential target for antisense therapy

8 July 2018

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STAT3-mediated transcription of Bcl-2, Mcl-1 and c-IAP2 prevents apoptosis in polyamine-depleted cells

8 July 2018

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BAY 43-9006 exhibits broad spectrum oral antitumor activity and targets the RAF/MEK/ERK pathway and receptor tyrosine kinases involved in tumor progression and angiogenesis

8 July 2018

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Death induction by recombinant native TRAIL and its prevention by a caspase 9 inhibitor in primary human esophageal epithelial cells

8 July 2018

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Regulation of the innate and adaptive immune responses by Stat-3 signaling in tumor cells

8 July 2018

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8 July 2018

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Constitutive activation of signal transducers and activators of transcription 3 correlates with cyclin D1 overexpression and may provide a novel prognostic marker in head and neck squamous cell carcinoma.

8 July 2018

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Identification of inhibitors of TRAIL-induced death (ITIDs) in the TRAIL-sensitive colon carcinoma cell line SW480 using a genetic approach.

8 July 2018

1 reference

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Apo2L/TRAIL-dependent recruitment of endogenous FADD and caspase-8 to death receptors 4 and 5.

8 July 2018

1 reference

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STAT3 is required for the gp130-mediated full activation of the c-myc gene

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3784419

A National Cancer Data Base report on 53,856 cases of thyroid carcinoma treated in the U.S., 1985-1995 [see commetns]

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3784419

Receptor-selective mutants of apoptosis-inducing ligand 2/tumor necrosis factor-related apoptosis-inducing ligand reveal a greater contribution of death receptor (DR) 5 than DR4 to apoptosis signaling

8 July 2018

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Crossref

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0075414

Bioluminescent molecular imaging of endogenous and exogenous p53-mediated transcription in vitro and in vivo using an HCT116 human colon carcinoma xenograft model

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24086526

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

TRAIL receptor-selective mutants signal to apoptosis via TRAIL-R1 in primary lymphoid malignancies

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24086526

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Mcl-1, Vascular Endothelial Growth Factor-R2, and 14-3-3 Expression Might Predict Primary Response against Radiotherapy and Chemotherapy in Patients with Locally Advanced Squamous Cell Carcinomas of the Head and Neck

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24086526

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based on heuristic

Identifiers

DOI

10.1371/JOURNAL.PONE.0075414

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24086526%20AND%20SRC:MED&resulttype=core&format=json

31 May 2020

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24086526%20AND%20SRC:MED&resulttype=core&format=json

31 May 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24086526%20AND%20SRC:MED&resulttype=core&format=json