Compensatory function of Pyk2 protein in the promotion of focal adhesion kinase (FAK)-null mammary cancer stem cell tumorigenicity and metastatic activity (Q34998069)

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English	Compensatory function of Pyk2 protein in the promotion of focal adhesion kinase (FAK)-null mammary cancer stem cell tumorigenicity and metastatic activity	scientific article

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scholarly article

1 reference

Europe PubMed Central

5 August 2017

Compensatory function of Pyk2 protein in the promotion of focal adhesion kinase (FAK)-null mammary cancer stem cell tumorigenicity and metastatic activity (English)

1 reference

Europe PubMed Central

5 August 2017

neoplastic stem cells

1 reference

based on heuristic

inferred from title

author name string

Huaping Fan

1

1 reference

Europe PubMed Central

5 August 2017

Jun-Lin Guan

2

1 reference

Europe PubMed Central

5 August 2017

language of work or name

0 references

publication date

6 April 2011

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Europe PubMed Central

5 August 2017

number of pages

10

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based on heuristic

inferred from page(s)

Journal of Biological Chemistry

1 reference

Europe PubMed Central

5 August 2017

286

1 reference

Europe PubMed Central

5 August 2017

21

1 reference

Europe PubMed Central

5 August 2017

18573-18582

1 reference

Europe PubMed Central

5 August 2017

Loss of miR-200 inhibition of Suz12 leads to polycomb-mediated repression required for the formation and maintenance of cancer stem cells

1 reference

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Role of focal adhesion kinase Ser-732 phosphorylation in centrosome function during mitosis

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Ras- and PI3K-dependent breast tumorigenesis in mice and humans requires focal adhesion kinase signaling.

1 reference

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Mammary epithelial-specific ablation of the focal adhesion kinase suppresses mammary tumorigenesis by affecting mammary cancer stem/progenitor cells

1 reference

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1 reference

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1 reference

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Compensatory role for Pyk2 during angiogenesis in adult mice lacking endothelial cell FAK.

1 reference

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Antitumor activity and pharmacology of a selective focal adhesion kinase inhibitor, PF-562,271

1 reference

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GATA-3 links tumor differentiation and dissemination in a luminal breast cancer model

1 reference

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PyK2 and FAK connections to p190Rho guanine nucleotide exchange factor regulate RhoA activity, focal adhesion formation, and cell motility

1 reference

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Mammary epithelial-specific disruption of the focal adhesion kinase blocks mammary tumor progression

1 reference

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The genomic landscapes of human breast and colorectal cancers

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Molecular heterogeneity of breast carcinomas and the cancer stem cell hypothesis

1 reference

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Focal adhesion kinase and p53 signaling in cancer cells

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Cellular characterization of a novel focal adhesion kinase inhibitor

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WNT/beta-catenin mediates radiation resistance of mouse mammary progenitor cells

1 reference

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Glioma stem cells promote radioresistance by preferential activation of the DNA damage response

1 reference

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Cancer stem cells: models and concepts

1 reference

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The signaling and biological implications of FAK overexpression in cancer

1 reference

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Cancer stem cells: an old idea--a paradigm shift

1 reference

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Endothelial FAK is essential for vascular network stability, cell survival, and lamellipodial formation.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3099673

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Mechanisms of focal adhesion kinase regulation

1 reference

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Exploiting the PI3K/AKT pathway for cancer drug discovery

1 reference

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The role of focal-adhesion kinase in cancer - a new therapeutic opportunity

1 reference

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Conditional knockout of focal adhesion kinase in endothelial cells reveals its role in angiogenesis and vascular development in late embryogenesis

1 reference

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Tumour stem cells and drug resistance

1 reference

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Multiple connections link FAK to cell motility and invasion

1 reference

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1 reference

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Focal adhesion kinase: the first ten years

1 reference

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1 reference

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Biochemical signals and biological responses elicited by the focal adhesion kinase

1 reference

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Pyk2 and FAK differentially regulate progression of the cell cycle.

1 reference

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Anti-apoptotic role of focal adhesion kinase (FAK). Induction of inhibitor-of-apoptosis proteins and apoptosis suppression by the overexpression of FAK in a human leukemic cell line, HL-60.

1 reference

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Suppression of ultraviolet irradiation-induced apoptosis by overexpression of focal adhesion kinase in Madin-Darby canine kidney cells

1 reference

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Pyk2 and Src-family protein-tyrosine kinases compensate for the loss of FAK in fibronectin-stimulated signaling events but Pyk2 does not fully function to enhance FAK- cell migration

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3099673

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Differential regulation of Pyk2 and focal adhesion kinase (FAK). The C-terminal domain of FAK confers response to cell adhesion

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3099673

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Identification of p130Cas as a mediator of focal adhesion kinase-promoted cell migration

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3099673

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Paxillin is tyrosine-phosphorylated by and preferentially associates with the calcium-dependent tyrosine kinase in rat liver epithelial cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3099673

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Inhibition of cyclin D1 phosphorylation on threonine-286 prevents its rapid degradation via the ubiquitin-proteasome pathway

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3099673

8 July 2018

The related adhesion focal tyrosine kinase is tyrosine-phosphorylated after beta1-integrin stimulation in B cells and binds to p130cas

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3099673

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The related adhesion focal tyrosine kinase forms a complex with paxillin in hematopoietic cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3099673

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Phosphorylation of tyrosine 397 in focal adhesion kinase is required for binding phosphatidylinositol 3-kinase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3099673

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Control of adhesion-dependent cell survival by focal adhesion kinase

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3099673

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1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3099673

8 July 2018

Direct interaction of v-Src with the focal adhesion kinase mediated by the Src SH2 domain

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3099673

8 July 2018

Association of focal adhesion kinase with its potential substrate phosphatidylinositol 3-kinase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3099673

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Autophosphorylation of the focal adhesion kinase, pp125FAK, directs SH2-dependent binding of pp60src

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3099673

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Tyrosine phosphorylation of the novel protein-tyrosine kinase RAFTK during an early phase of platelet activation by an integrin glycoprotein IIb-IIIa-independent mechanism.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.200717

21 January 2018

Cytotoxic T lymphocytes express a beta3 integrin which can induce the phosphorylation of focal adhesion kinase and the related PYK-2

1 reference

https://pubmed.ncbi.nlm.nih.gov/21471206

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Requirement of phosphatidylinositol 3-kinase in focal adhesion kinase-promoted cell migration

1 reference

https://pubmed.ncbi.nlm.nih.gov/21471206

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1074/JBC.M110.200717

1 reference

Europe PubMed Central

5 August 2017

1 reference

Europe PubMed Central

5 August 2017

1 reference

Europe PubMed Central

5 August 2017

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