Mitochondrial DNA repair and aging (Q34994585)

5 August 2017

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title

Mitochondrial DNA repair and aging (English)

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5 August 2017

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Bhaskar S Mandavilli

1

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5 August 2017

Janine H Santos

series ordinal

2

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5 August 2017

Bennett Van Houten

series ordinal

3

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5 August 2017

language of work or name

English

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publication date

1 November 2002

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5 August 2017

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5 August 2017

509

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5 August 2017

1-2

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5 August 2017

127-151

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Aging: a theory based on free radical and radiation chemistry

5 August 2017

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900220-8

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900220-8

Free radical theory of aging

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900220-8

The free radical theory of aging matures

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900220-8

Mitochondrial free radical generation, oxidative stress, and aging

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900220-8

The cellular production of hydrogen peroxide

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900220-8

The biologic clock: the mitochondria?

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900220-8

Mitochondrial role in cell aging

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900220-8

An integrated theory of aging as the result of mitochondrial-DNA mutation in differentiated cells.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900220-8

Is cell aging caused by respiration-dependent injury to the mitochondrial genome?

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900220-8

A two-step hypothesis on the mechanisms of in vitro cell aging: cell differentiation followed by intrinsic mitochondrial mutagenesis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900220-8

Normal oxidative damage to mitochondrial and nuclear DNA is extensive

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900220-8

Mitochondrial mutations may increase oxidative stress: implications for carcinogenesis and aging?

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900220-8

Age-associated oxygen damage and mutations in mitochondrial DNA in human hearts

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900220-8

Oxidative damage to mitochondrial DNA shows marked age-dependent increases in human brain.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900220-8

Oxidative damage to mitochondrial DNA is increased in Alzheimer's disease

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900220-8

Multiple deletions are detectable in mitochondrial DNA of aging mice

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900220-8

Mitochondrial complex I deficiency in Parkinson's disease

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900220-8

7 January 2021

Mitochondrial disorders

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900220-8

Leber's hereditary optic neuroretinopathy, a maternally inherited disease. A genealogic study in four pedigrees

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900220-8

Mitochondrial DNA mutation associated with Leber's hereditary optic neuropathy

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900220-8

Deletions of muscle mitochondrial DNA

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900220-8

Accumulation of deletions and point mutations in mitochondrial genome in degenerative diseases.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900220-8

Mitochondrial DNA rearrangements in aging human brain and in situ PCR of mtDNA

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900220-8

Mitochondrial genome mutation in cell death and aging

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900220-8

Diseases of the mitochondrial DNA.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900220-8

Generation of superoxide anion by the NADH dehydrogenase of bovine heart mitochondria

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900220-8

Protection of DNA damage by dietary restriction

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900220-8

A pattern of accumulation of a somatic deletion of mitochondrial DNA in aging human tissues

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900220-8

Simultaneous increase of mitochondrial DNA deletions and lipid peroxidation in human aging

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900220-8

Antioxidant defense mechanisms: a new thiol-specific antioxidant enzyme.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900220-8

Preferential alkylation of mitochondrial deoxyribonucleic acid by N-methyl-N-nitrosourea

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900220-8

Covalent binding of polycyclic aromatic compounds to mitochondrial and nuclear DNA.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900220-8

Mitochondrial DNA is a major cellular target for a dihydrodiol-epoxide derivative of benzo[a]pyrene.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900220-8

Strand breaks of mammalian mitochondrial DNA induced by carcinogens

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900220-8

Manifestation of carcinogenesis as a stochastic process on the basis of an altered mitochondrial genome

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900220-8

Preferential attack of mitochondrial DNA by aflatoxin B1 during hepatocarcinogenesis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900220-8

Mitochondrial reduction of the carcinogen chromate: formation of chromium(V)

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900220-8

Free-radical metabolism of carbon tetrachloride in rat liver mitochondria. A study of the mechanism of activation.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900220-8

Mitochondrial DNA in human malignancy.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900220-8

Iron toxicity and oxygen radicals

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900220-8

Damage to DNA by reactive oxygen and nitrogen species: role in inflammatory disease and progression to cancer

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900220-8

Massive conversion of guanosine to 8-hydroxy-guanosine in mouse liver mitochondrial DNA by administration of azidothymidine

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900220-8

Oxidants, antioxidants, and the degenerative diseases of aging

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900220-8

Fragmented mitochondrial DNA is the predominant carrier of oxidized DNA bases

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900220-8

Oxidative damage to DNA during aging: 8-hydroxy-2'-deoxyguanosine in rat organ DNA and urine

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900220-8

Genetic and functional changes in mitochondria associated with aging

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900220-8

Mitochondrial damage as a source of diseases and aging: a strategy of how to fight these

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900220-8

Measurement of oxidatively induced base lesions in liver from Wistar rats of different ages

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900220-8

DNA oxidation matters: the HPLC-electrochemical detection assay of 8-oxo-deoxyguanosine and 8-oxo-guanine

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900220-8

Endogenous oxidative damage of mtDNA.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900220-8

Detection and quantification of oxidative adducts of mitochondrial DNA.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900220-8

Mitochondrial endogenous oxidative damage has been overestimated

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900220-8

Does oxidative damage to DNA increase with age?

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900220-8

Analysis of gene-specific DNA damage and repair using quantitative polymerase chain reaction

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900220-8

Mitochondrial DNA damage is more extensive and persists longer than nuclear DNA damage in human cells following oxidative stress

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900220-8

Preferential mitochondrial DNA injury caused by glucose oxidase as a steady generator of hydrogen peroxide in human fibroblasts

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900220-8

DNA damage in brain mitochondria caused by aging and MPTP treatment.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900220-8

Aging, oxidative responses, and proliferative capacity in cultured mouse aortic smooth muscle cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900220-8

Hydrogen peroxide causes significant mitochondrial DNA damage in human RPE cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900220-8

Hydrogen peroxide- and peroxynitrite-induced mitochondrial DNA damage and dysfunction in vascular endothelial and smooth muscle cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900220-8

Bcl-2 facilitates recovery from DNA damage after oxidative stress

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900220-8

Repair of DNA damage in mitochondria

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900220-8

Relative susceptibilities of mitochondrial and nuclear DNA to damage induced by hydrogen peroxide in two mouse germ cell lines

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900220-8

Rod outer segments mediate mitochondrial DNA damage and apoptosis in human retinal pigment epithelium

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900220-8

Mouse models for mitochondrial disease

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900220-8

Mitochondrial DNA mutations in human disease.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900220-8

Mitochondrial diseases in man and mouse

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900220-8

Mitochondria and degenerative disorders

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900220-8

Nuclear genetic defects of oxidative phosphorylation

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900220-8

Diseases caused by nuclear genes affecting mtDNA stability

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900220-8

Respiratory chain complex I deficiency

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900220-8

Deficiency of subunits in heart mitochondrial NADH-ubiquinone oxidoreductase of a patient with mitochondrial encephalomyopathy and cardiomyopathy.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900220-8

Maternal inheritance of deleted mitochondrial DNA in a family with mitochondrial myopathy

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900220-8

Pearson's marrow-pancreas syndrome. A multisystem mitochondrial disorder in infancy

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900220-8

Mitochondrial DNA mutation and the ageing process: bioenergy and pharmacological intervention

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900220-8

Deleterious mitochondrial DNA mutations accumulate in aging human tissues

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900220-8

Ageing-associated 5 kb deletion in human liver mitochondrial DNA.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900220-8

An age-associated correlation between cellular bioenergy decline and mtDNA rearrangements in human skeletal muscle

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900220-8

Human mtDNA sublimons resemble rearranged mitochondrial genoms found in pathological states

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900220-8

The relationship between somatic mtDNA rearrangements, human heart disease and aging

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900220-8

Mitochondrial myopathy of childhood associated with depletion of mitochondrial DNA

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900220-8

Mitochondrial DNA mutations as an important contributor to ageing and degenerative diseases

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900220-8

High aggregate burden of somatic mtDNA point mutations in aging and Alzheimer's disease brain

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900220-8

Facile detection of mitochondrial DNA mutations in tumors and bodily fluids

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900220-8

Somatic mutations of the mitochondrial genome in human colorectal tumours

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900220-8

Microsatellite instability in the mitochondrial DNA of colorectal carcinomas: evidence for mismatch repair systems in mitochondrial genome.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900220-8

Unique mutations in mitochondrial DNA of senescence-accelerated mouse (SAM) strains

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900220-8

The absence of a pyrimidine dimer repair mechanism in mammalian mitochondria

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900220-8

Repair of pyrimidine dimers in nuclear and mitochondrial DNA of yeast irradiated with low doses of ultraviolet light

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900220-8

Repair of alkylation and oxidative damage in mitochondrial DNA.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900220-8

Mitochondrial DNA repair pathways.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900220-8

Repair of mtDNA in vertebrates

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900220-8

Enzymology of mitochondrial base excision repair

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900220-8

Base excision repair in nuclear and mitochondrial DNA.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900220-8

Base excision repair of mitochondrial DNA damage in mammalian cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900220-8

Regulation of intracellular localization of human MTH1, OGG1, and MYH proteins for repair of oxidative DNA damage

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900220-8

Mapping oxidative DNA damage using ligation-mediated polymerase chain reaction technology

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900220-8

Repair of mitochondrial DNA after various types of DNA damage in Chinese hamster ovary cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900220-8

Glial cell type-specific responses to menadione-induced oxidative stress

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900220-8

Glial cell-specific differences in response to alkylation damage.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900220-8

Efficient repair of abasic sites in DNA by mitochondrial enzymes

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900220-8

The mitochondrial p55 accessory subunit of human DNA polymerase gamma enhances DNA binding, promotes processive DNA synthesis, and confers N-ethylmaleimide resistance

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900220-8

Identification of 5'-deoxyribose phosphate lyase activity in human DNA polymerase gamma and its role in mitochondrial base excision repair in vitro

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900220-8

Insertion of specific bases during DNA synthesis past the oxidation-damaged base 8-oxodG

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900220-8

Mutagenesis by 8-oxoguanine: an enemy within

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900220-8

DNA glycosylases in the base excision repair of DNA

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900220-8

Repair of oxidative damage to DNA: enzymology and biology

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900220-8

Multiple DNA glycosylases for repair of 8-oxoguanine and their potential in vivo functions

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900220-8

Gene-specific nuclear and mitochondrial repair of formamidopyrimidine DNA glycosylase-sensitive sites in Chinese hamster ovary cells.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900220-8

Expression and differential intracellular localization of two major forms of human 8-oxoguanine DNA glycosylase encoded by alternatively spliced OGG1 mRNAs

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900220-8

Accumulation of premutagenic DNA lesions in mice defective in removal of oxidative base damage

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900220-8

Mammalian Ogg1/Mmh gene plays a major role in repair of the 8-hydroxyguanine lesion in DNA.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900220-8

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900220-8

DNA repair and aging in mouse liver: 8-oxodG glycosylase activity increase in mitochondrial but not in nuclear extracts

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900220-8

Enhanced mitochondrial DNA repair and cellular survival after oxidative stress by targeting the human 8-oxoguanine glycosylase repair enzyme to mitochondria.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900220-8

Comparison of base-excision repair capacity in proliferating and differentiated PC 12 cells following acute challenge with dieldrin

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900220-8

Purification and properties of mitochondrial uracil-DNA glycosylase from rat liver

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900220-8

Affinity purification and comparative analysis of two distinct human uracil-DNA glycosylases.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900220-8

Regulation of expression of nuclear and mitochondrial forms of human uracil-DNA glycosylase

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900220-8

Human mitochondrial uracil-DNA glycosylase preform (UNG1) is processed to two forms one of which is resistant to inhibition by AP sites

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900220-8

Nuclear and mitochondrial splice forms of human uracil-DNA glycosylase contain a complex nuclear localisation signal and a strong classical mitochondrial localisation signal, respectively

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900220-8

Mitochondrial targeting of human DNA glycosylases for repair of oxidative DNA damage

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900220-8

Human APE2 protein is mostly localized in the nuclei and to some extent in the mitochondria, while nuclear APE2 is partly associated with proliferating cell nuclear antigen

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900220-8

Mitochondrial localization of APE/Ref-1 in thyroid cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900220-8

The redox and DNA-repair activities of Ref-1 are encoded by nonoverlapping domains

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900220-8

Activation of apurinic/apyrimidinic endonuclease in human cells by reactive oxygen species and its correlation with their adaptive response to genotoxicity of free radicals

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900220-8

The accessory subunit of Xenopus laevis mitochondrial DNA polymerase gamma increases processivity of the catalytic subunit of human DNA polymerase gamma and is related to class II aminoacyl-tRNA synthetases

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900220-8

Characterization of a catalytically slow AP lyase activity in DNA polymerase gamma and other family A DNA polymerases

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900220-8

Mutation of POLG is associated with progressive external ophthalmoplegia characterized by mtDNA deletions

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900220-8

Mutations at the mitochondrial DNA polymerase (POLG) locus associated with male infertility

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900220-8

A DNA ligase from mitochondria of rat liver

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900220-8

The human DNA ligase III gene encodes nuclear and mitochondrial proteins

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900220-8

Antisense-mediated decrease in DNA ligase III expression results in reduced mitochondrial DNA integrity

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900220-8

An interaction between the mammalian DNA repair protein XRCC1 and DNA ligase III

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900220-8

Mitochondrial DNA ligase III function is independent of Xrcc1.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900220-8

Two forms of mitochondrial DNA ligase III are produced in Xenopus laevis oocytes

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900220-8

Superoxide radical and superoxide dismutases

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900220-8

Mice lacking extracellular superoxide dismutase are more sensitive to hyperoxia

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900220-8

Early decrease of redox factor-1 in spinal motor neurons of presymptomatic transgenic mice with a mutant SOD1 gene.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900220-8

Rats expressing human cytosolic copper-zinc superoxide dismutase transgenes with amyotrophic lateral sclerosis: associated mutations develop motor neuron disease

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900220-8

Amyotrophic lateral sclerosis and structural defects in Cu,Zn superoxide dismutase

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900220-8

Mutations in Cu/Zn superoxide dismutase gene are associated with familial amyotrophic lateral sclerosis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900220-8

Mutant CuZn superoxide dismutase in motor neuron disease

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900220-8

Relationship of microglial and astrocytic activation to disease onset and progression in a transgenic model of familial ALS.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900220-8

Oxidative inactivation of calcineurin by Cu,Zn superoxide dismutase G93A, a mutant typical of familial amyotrophic lateral sclerosis.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900220-8

Mice with a partial deficiency of manganese superoxide dismutase show increased vulnerability to the mitochondrial toxins malonate, 3-nitropropionic acid, and MPTP.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900220-8

Dilated cardiomyopathy and neonatal lethality in mutant mice lacking manganese superoxide dismutase

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900220-8

Mitochondrial disease in superoxide dismutase 2 mutant mice

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900220-8

Neurodegeneration, myocardial injury, and perinatal death in mitochondrial superoxide dismutase-deficient mice

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900220-8

A novel neurological phenotype in mice lacking mitochondrial manganese superoxide dismutase

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900220-8

Lifespan extension and rescue of spongiform encephalopathy in superoxide dismutase 2 nullizygous mice treated with superoxide dismutase-catalase mimetics.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900220-8

Increased mitochondrial oxidative stress in the Sod2 (+/-) mouse results in the age-related decline of mitochondrial function culminating in increased apoptosis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900220-8

Increased sensitivity of homozygous Sod2 mutant mice to oxygen toxicity

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900220-8

Mice deficient in cellular glutathione peroxidase develop normally and show no increased sensitivity to hyperoxia

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900220-8

Mitochondrial oxidative stress in mice lacking the glutathione peroxidase-1 gene

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900220-8

A mouse model for mitochondrial myopathy and cardiomyopathy resulting from a deficiency in the heart/muscle isoform of the adenine nucleotide translocator

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900220-8

Up-regulation of nuclear and mitochondrial genes in the skeletal muscle of mice lacking the heart/muscle isoform of the adenine nucleotide translocator

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900220-8

Mitochondrial disease in mouse results in increased oxidative stress

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900220-8

Molecular genetics of life span in C. elegans: how much does it teach us?

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900220-8

daf-2, an insulin receptor-like gene that regulates longevity and diapause in Caenorhabditis elegans

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900220-8

A phosphatidylinositol-3-OH kinase family member regulating longevity and diapause in Caenorhabditis elegans

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900220-8

A mutation in succinate dehydrogenase cytochrome b causes oxidative stress and ageing in nematodes

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900220-8

Mitochondrial mutations differentially affect aging, mutability and anesthetic sensitivity in Caenorhabditis elegans

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900220-8

Extension of life-span in Caenorhabditis elegans by a diet lacking coenzyme Q.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900220-8

Mouse coq7/clk-1 orthologue rescued slowed rhythmic behavior and extended life span of clk-1 longevity mutant in Caenorhabditis elegans

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900220-8

Aging and resistance to oxidative damage in Caenorhabditis elegans

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900220-8

The daf-2 gene network for longevity regulates oxidative stress resistance and Mn-superoxide dismutase gene expression in Caenorhabditis elegans.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900220-8

GAS-1: a mitochondrial protein controls sensitivity to volatile anesthetics in the nematode Caenorhabditis elegans

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900220-8

Mitochondrial expression and function of GAS-1 in Caenorhabditis elegans

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900220-8

Coenzyme Q is an obligatory cofactor for uncoupling protein function

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900220-8

A dietary source of coenzyme Q is essential for growth of long-lived Caenorhabditis elegans clk-1 mutants

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900220-8

A new member of the family of di-iron carboxylate proteins. Coq7 (clk-1), a membrane-bound hydroxylase involved in ubiquinone biosynthesis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900220-8

Altered quinone biosynthesis in the long-lived clk-1 mutants of Caenorhabditis elegans.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900220-8

Mutations conferring new patterns of sensitivity to volatile anesthetics in Caenorhabditis elegans.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900220-8

A defect in the cytochrome b large subunit in complex II causes both superoxide anion overproduction and abnormal energy metabolism in Caenorhabditis elegans

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900220-8

clk-1, mitochondria, and physiological rates

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900220-8

Structural and functional conservation of the Caenorhabditis elegans timing gene clk-1.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900220-8

The COQ7 gene encodes a protein in saccharomyces cerevisiae necessary for ubiquinone biosynthesis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900220-8

Apparent uncoupling of energy production and consumption in long-lived Clk mutants of Caenorhabditis elegans.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900220-8

CLK-1 controls respiration, behavior and aging in the nematode Caenorhabditis elegans

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900220-8

Conservation of the Caenorhabditis elegans timing gene clk-1 from yeast to human: a gene required for ubiquinone biosynthesis with potential implications for aging

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900220-8

Yeast Clk-1 homologue (Coq7/Cat5) is a mitochondrial protein in coenzyme Q synthesis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900220-8

Mouse homologue of coq7/clk-1, longevity gene in Caenorhabditis elegans, is essential for coenzyme Q synthesis, maintenance of mitochondrial integrity, and neurogenesis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900220-8

Oxidative stress and ageing in Caenorhabditis elegans

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900220-8

Cloning, expression, and characterization of two manganese superoxide dismutases from Caenorhabditis elegans

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900220-8

Extension of Life-Span with Superoxide Dismutase/Catalase Mimetics

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900220-8

Mitochondrial superoxide and hydrogen peroxide generation, protein oxidative damage, and longevity in different species of flies

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900220-8

Selectivity of protein oxidative damage during aging in Drosophila melanogaster

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900220-8

Age-specific decrease in aerobic efficiency associated with increase in oxygen free radical production in Drosophila melanogaster.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900220-8

Extension of life-span by overexpression of superoxide dismutase and catalase in Drosophila melanogaster.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900220-8

Overexpression of Mn-containing superoxide dismutase in transgenic Drosophila melanogaster

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900220-8

Calendar life span versus budding life span of Saccharomyces cerevisiae

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900220-8

Superoxide dismutase activity is essential for stationary phase survival in Saccharomyces cerevisiae. Mitochondrial production of toxic oxygen species in vivo

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900220-8

Mitochondrial superoxide decreases yeast survival in stationary phase

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900220-8

Effect of Cu,Zn superoxide dismutase disruption mutation on replicative senescence in Saccharomyces cerevisiae.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900220-8

Aged mother cells of Saccharomyces cerevisiae show markers of oxidative stress and apoptosis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900220-8

The Saccharomyces cerevisiae homologues of endonuclease III from Escherichia coli, Ntg1 and Ntg2, are both required for efficient repair of spontaneous and induced oxidative DNA damage in yeast

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900220-8

Saccharomyces cerevisiae Ntg1p and Ntg2p: broad specificity N-glycosylases for the repair of oxidative DNA damage in the nucleus and mitochondria

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900220-8

Inactivation of Saccharomyces cerevisiae OGG1 DNA repair gene leads to an increased frequency of mitochondrial mutants.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900220-8

RAG1 and RAG2: nuclear genes involved in the dependence/independence on mitochondrial respiratory function for growth on sugars.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900220-8

The mitochondrial genotype can influence nuclear gene expression in yeast.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900220-8

RTG1 and RTG2: two yeast genes required for a novel path of communication from mitochondria to the nucleus

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900220-8

A basic helix-loop-helix-leucine zipper transcription complex in yeast functions in a signaling pathway from mitochondria to the nucleus

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900220-8

Enzymatic and metabolic studies on retrograde regulation mutants of yeast

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900220-8

RTG genes in yeast that function in communication between mitochondria and the nucleus are also required for expression of genes encoding peroxisomal proteins

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900220-8

Glutathione depletion in PC12 results in selective inhibition of mitochondrial complex I activity. Implications for Parkinson's disease.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900220-8

Gene expression profile of aging and its retardation by caloric restriction

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900220-8

Gene-expression profile of the ageing brain in mice

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900220-8

Genome-wide study of aging and oxidative stress response in Drosophila melanogaster

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900220-8

Genome-wide responses to mitochondrial dysfunction

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900220-8

Chronic systemic pesticide exposure reproduces features of Parkinson's disease

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900220-8

Incorporation of tritiated dimethylnitrosamine into subcellular fractions of mouse liver after long term administration of dimethylnitrosamine

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900220-8

inferred from DOI database lookup

7 January 2021

based on heuristic

Metabolic control and gene dysregulation in yeast aging

1 reference

https://api.crossref.org/works/10.1016%2FS0027-5107%2802%2900220-8

inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1016/S0027-5107(02)00220-8

1 reference

5 August 2017

1 reference