Role of cannabis and endocannabinoids in the genesis of schizophrenia (Q34993855)

5 August 2017

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title

Role of cannabis and endocannabinoids in the genesis of schizophrenia (English)

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5 August 2017

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Bart A Ellenbroek

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María-Paz Viveros

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Maria-Paz Viveros

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author name string

Emilio Fernandez-Espejo

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5 August 2017

Luis Núñez

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5 August 2017

Fernando Rodriguez de Fonseca

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5 August 2017

24 July 2009

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5 August 2017

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5 August 2017

206

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5 August 2017

531-549

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5 August 2017

4

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https://scigraph.springernature.com/pub.10.1007/s00213-009-1612-6

5 August 2017

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cites work

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The cannabinoid agonist WIN 55,212-2 reduces sensorimotor gating and recognition memory in rats.

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Differing effects of the cannabinoid agonist, CP 55,940, in an alcohol or Tween 80 solvent, on prepulse inhibition of the acoustic startle reflex in the rat.

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Molecular composition of the endocannabinoid system at glutamatergic synapses.

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Delta-9-tetrahydrocannabinol effects in schizophrenia: Implications for cognition, psychosis, and addiction

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12 December 2020

Cannabis use and psychosis.

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12 December 2020

Effects of the cannabinoid CB1 receptor antagonist SR141716A on the behavior of pigeons and rats.

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12 December 2020

Anandamide levels in cerebrospinal fluid of first-episode schizophrenic patients: impact of cannabis use.

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12 December 2020

Cannabis and the brain

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Cannabis use and risk of psychotic or affective mental health outcomes: a systematic review

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Altered motor activity, exploration and anxiety in heterozygous neuregulin 1 mutant mice: implications for understanding schizophrenia.

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12 December 2020

LY320135, a novel cannabinoid CB1 receptor antagonist, unmasks coupling of the CB1 receptor to stimulation of cAMP accumulation

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12 December 2020

Endocannabinoid signalling in the blood of patients with schizophrenia

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12 December 2020

An anorexic lipid mediator regulated by feeding.

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12 December 2020

Cannabinoids modulate synaptic strength and plasticity at glutamatergic synapses of rat prefrontal cortex pyramidal neurons.

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12 December 2020

Adolescence and mental illness.

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12 December 2020

Localization and mechanisms of action of cannabinoid receptors at the glutamatergic synapses of the mouse nucleus accumbens.

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Psychiatric symptoms in cannabis users

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Psychiatric morbidity in the first-degree relatives of schizophrenic patients

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12 December 2020

Activation of cannabinoid-1 receptors disrupts sensory gating and neuronal oscillation: relevance to schizophrenia.

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12 December 2020

Neuropsychobiological evidence for the functional presence and expression of cannabinoid CB2 receptors in the brain

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12 December 2020

Cannabis use in adolescence and risk for adult psychosis: longitudinal prospective study

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Presidential Address, 1974. The more or less startling effects of weak prestimulation

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12 December 2020

Regulation of a neuronal form of focal adhesion kinase by anandamide

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12 December 2020

Deficient social and play behavior in juvenile and adult rats after neonatal cortical lesion: effects of chronic pubertal cannabinoid treatment.

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12 December 2020

Molecular characterization of a peripheral receptor for cannabinoids

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12 December 2020

The endocannabinoid system as a target for therapeutic drugs.

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12 December 2020

Impaired visual object recognition and dorsal/ventral stream interaction in schizophrenia.

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12 December 2020

Studies on [3H]CP-55940 binding in the human central nervous system: regional specific changes in density of cannabinoid-1 receptors associated with schizophrenia and cannabis use.

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12 December 2020

Modulation of transmitter release via presynaptic cannabinoid receptors

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12 December 2020

Characterization and localization of cannabinoid receptors in rat brain: a quantitative in vitro autoradiographic study

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12 December 2020

Phasic versus tonic dopamine release and the modulation of dopamine system responsivity: a hypothesis for the etiology of schizophrenia

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12 December 2020

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Cannabis use and risk of psychosis in later life

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Reading the mind in cartoons and stories: an fMRI study of 'theory of mind' in verbal and nonverbal tasks

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Clozapine decreases [3H] CP 55940 binding to the cannabinoid 1 receptor in the rat nucleus accumbens.

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12 December 2020

Chronic cannabinoid exposure produces lasting memory impairment and increased anxiety in adolescent but not adult rats

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12 December 2020

D2 dopamine receptors modulate Galpha-subunit coupling of the CB1 cannabinoid receptor

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12 December 2020

Altered brain tissue composition in heavy marijuana users

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12 December 2020

Lack of CB1 cannabinoid receptor impairs cocaine self-administration.

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12 December 2020

Changing incidence of psychotic disorders among the young in Zurich

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12 December 2020

Anandamide inhibits metabolism and physiological actions of 2-arachidonoylglycerol in the striatum

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12 December 2020

Endocannabinoid signaling in the brain

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12 December 2020

Cannabinoid transmission and reward-related events.

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12 December 2020

Sensory gating and its modulation by cannabinoids: electrophysiological, computational and mathematical analysis.

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12 December 2020

Role of the endogenous cannabinoid system in the regulation of motor activity.

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12 December 2020

Increased cannabinoid receptor density in the posterior cingulate cortex in schizophrenia.

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12 December 2020

Strain-specific effects of amphetamine on prepulse inhibition and patterns of locomotor behavior in mice

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12 December 2020

Dopaminergic stimulation disrupts sensorimotor gating in the rat

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12 December 2020

Determination and characterization of a cannabinoid receptor in rat brain

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12 December 2020

Activation of CB1 cannabinoid receptors in rat hippocampal slices inhibits potassium-evoked cholecystokinin release, a possible mechanism contributing to the spatial memory defects produced by cannabinoids.

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12 December 2020

Sensorimotor gating in mice is disrupted after AM404, an anandamide reuptake and degradation inhibitor

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12 December 2020

Drug-induced potentiation of prepulse inhibition of acoustic startle reflex in mice: a model for detecting antipsychotic activity?

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12 December 2020

Cannabis and psychosis. Is there epidemiological evidence for an association?

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12 December 2020

Increased caudate dopamine D2 receptor availability as a genetic marker for schizophrenia

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12 December 2020

Two cases of "cannabis acute psychosis" following the administration of oral cannabis

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12 December 2020

Cannabinoid receptor antagonists counteract sensorimotor gating deficits in the phencyclidine model of psychosis.

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12 December 2020

FAAH and anandamide: is 2-AG really the odd one out?

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12 December 2020

Windows of vulnerability to psychopathology and therapeutic strategy in the adolescent rodent model

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12 December 2020

Activation of corticotropin-releasing factor in the limbic system during cannabinoid withdrawal

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12 December 2020

Blunted psychotomimetic and amnestic effects of delta-9-tetrahydrocannabinol in frequent users of cannabis

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12 December 2020

Being the target of another's emotion: a PET study.

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12 December 2020

Cannabis and cognitive functions: a re-evaluation study

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12 December 2020

Heterozygous neuregulin 1 mice are more sensitive to the behavioural effects of Delta9-tetrahydrocannabinol.

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12 December 2020

The endogenous cannabinoid system controls extinction of aversive memories

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12 December 2020

Antipsychotic drug effects on brain morphology in first-episode psychosis

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12 December 2020

Cerebrospinal anandamide levels are elevated in acute schizophrenia and are inversely correlated with psychotic symptoms

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12 December 2020

Identification of an endogenous 2-monoglyceride, present in canine gut, that binds to cannabinoid receptors

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12 December 2020

Cannabis and cognitive dysfunction: parallels with endophenotypes of schizophrenia?

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12 December 2020

Excessive brain volume loss over time in cannabis-using first-episode schizophrenia patients

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12 December 2020

Cannabis and brain morphology in recent-onset schizophrenia

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12 December 2020

Early adolescent cannabis exposure and positive and negative dimensions of psychosis.

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12 December 2020

Substance use in a population-based clinic sample of people with first-episode psychosis

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12 December 2020

Prevalence and correlates of cannabis use in developed and developing countries

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12 December 2020

Cannabinoid CB1 receptor antagonism markedly increases dopamine receptor-mediated stereotypies

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12 December 2020

Cannabis use predicts future psychotic symptoms, and vice versa

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12 December 2020

Impact of substance use on the onset and course of early psychosis

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12 December 2020

Behavioural effects of quinpirole following withdrawal of chronic treatment with the CB1 agonist, HU-210, in rats.

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12 December 2020

Repeated cannabinoid exposure during perinatal, adolescent or early adult ages produces similar longlasting deficits in object recognition and reduced social interaction in rats.

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12 December 2020

Causal relationship between cannabis use and psychotic symptoms or depression. Should we wait and see? A public health perspective.

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12 December 2020

Self reported cannabis use as a risk factor for schizophrenia in Swedish conscripts of 1969: historical cohort study

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12 December 2020

Effects of frequent marijuana use on brain tissue volume and composition

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12 December 2020

The molecular logic of endocannabinoid signalling

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12 December 2020

Heterozygous neuregulin 1 mice display greater baseline and Delta(9)-tetrahydrocannabinol-induced c-Fos expression.

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12 December 2020

Cognitive functioning of long-term heavy cannabis users seeking treatment.

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12 December 2020

2-Arachidonoylglycerol: a possible endogenous cannabinoid receptor ligand in brain

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12 December 2020

Elevated endogenous cannabinoids in schizophrenia

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12 December 2020

Neuregulins: functions, forms, and signaling strategies

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12 December 2020

Abnormalities in the thalamus and prefrontal cortex during episodic object recognition in schizophrenia.

1 reference

12 December 2020

The endocannabinoid anandamide inhibits neuronal progenitor cell differentiation through attenuation of the Rap1/B-Raf/ERK pathway.

1 reference

12 December 2020

Long-term cannabis use and mental health.

1 reference

12 December 2020

Cannabis use and brain structural alterations in first episode schizophrenia--a region of interest, voxel based morphometric study.

1 reference

12 December 2020

Cannabinoid receptor 1 gene (CNR1) and susceptibility to a quantitative phenotype for hebephrenic schizophrenia

1 reference

12 December 2020

Differential effects of direct and indirect dopamine agonists on prepulse inhibition: a study in D1 and D2 receptor knock-out mice

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12 December 2020

Presence of cannabinoid binding sites in the brain from early postnatal ages.

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12 December 2020

Targeting the endocannabinoid system: to enhance or reduce?

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12 December 2020

Cannabis use and risk of psychosis: an etiological link?

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12 December 2020

Cannabis and schizophrenia: impact on onset, course, psychopathology and outcomes

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12 December 2020

Cannabis use and psychosis: a longitudinal population-based study.

1 reference

12 December 2020

Association analyses of the neuregulin 1 gene with schizophrenia and manic psychosis in a Hispanic population.

1 reference

12 December 2020

Reversal of dopamine D(2) receptor responses by an anandamide transport inhibitor

1 reference

12 December 2020

Pharmacological studies of prepulse inhibition models of sensorimotor gating deficits in schizophrenia: a decade in review

1 reference

12 December 2020

A comparison of olanzapine with haloperidol in cannabis-induced psychotic disorder: a double-blind randomized controlled trial.

1 reference

12 December 2020

Chronic treatment with CP 55,940 during the peri-adolescent period differentially affects the behavioural responses of male and female rats in adulthood

1 reference

12 December 2020

Cannabinoids excite dopamine neurons in the ventral tegmentum and substantia nigra

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12 December 2020

The CNR1 gene as a pharmacogenetic factor for antipsychotics rather than a susceptibility gene for schizophrenia

1 reference

12 December 2020

Tests of causal linkages between cannabis use and psychotic symptoms

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12 December 2020

Animal models in the genomic era: possibilities and limitations with special emphasis on schizophrenia

1 reference

12 December 2020

Psychological and social sequelae of cannabis and other illicit drug use by young people: a systematic review of longitudinal, general population studies

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12 December 2020

Exogenous and endogenous cannabinoids control synaptic transmission in mice nucleus accumbens.

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12 December 2020

Effects of cannabinoid receptor ligands on psychosis-relevant behavior models in the rat.

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12 December 2020

Cannabis-sensitive dopaminergic markers in postmortem central nervous system: changes in schizophrenia

1 reference

12 December 2020

Auditory gating in rat hippocampus and medial prefrontal cortex: effect of the cannabinoid agonist WIN55,212-2.

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12 December 2020

The therapeutic potential of drugs that target cannabinoid receptors or modulate the tissue levels or actions of endocannabinoids

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12 December 2020

The hypothalamic levels of the endocannabinoid, anandamide, peak immediately before the onset of puberty in female rats

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12 December 2020

Endocannabinoid-mediated short-term synaptic plasticity: depolarization-induced suppression of inhibition (DSI) and depolarization-induced suppression of excitation (DSE)

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12 December 2020

CB1 cannabinoid receptors and on-demand defense against excitotoxicity

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12 December 2020

Activation of the cannabinoid receptor type 1 decreases glutamatergic and GABAergic synaptic transmission in the lateral amygdala of the mouse

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12 December 2020

The regulation of forebrain dopamine transmission: relevance to the pathophysiology and psychopathology of schizophrenia

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12 December 2020

Effect of cannabis use on health

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12 December 2020

Antipsychotic Drugs: Direct Correlation Between Clinical Potency and Presynaptic Action on Dopamine Neurons

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12 December 2020

Single photon emission computerized tomography imaging of amphetamine-induced dopamine release in drug-free schizophrenic subjects

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12 December 2020

Chronic pubertal, but not adult chronic cannabinoid treatment impairs sensorimotor gating, recognition memory, and the performance in a progressive ratio task in adult rats

1 reference

12 December 2020

Selective antagonist [3H]SR141716A binding to cannabinoid CB1 receptors is increased in the anterior cingulate cortex in schizophrenia

1 reference

12 December 2020

The Psychotomimetic Effects of Intravenous Delta-9-Tetrahydrocannabinol in Healthy Individuals: Implications for Psychosis

1 reference

12 December 2020

Early exposure to cannabis and risk for psychosis in young adolescents in Trinidad

1 reference

12 December 2020

Involvement of dopamine receptors in the antipsychotic profile of (-) eticlopride

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12 December 2020

Neuregulin 1 and susceptibility to schizophrenia

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12 December 2020

Expression of central and peripheral cannabinoid receptors in human immune tissues and leukocyte subpopulations

1 reference

12 December 2020

Cannabis and schizophrenia: towards a cannabinoid hypothesis of schizophrenia

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12 December 2020

Is schizophrenia due to excessive synaptic pruning in the prefrontal cortex? The Feinberg hypothesis revisited

1 reference

12 December 2020

Schizophrenia: caused by a fault in programmed synaptic elimination during adolescence?

1 reference

12 December 2020

Delta 9-tetrahydrocannabinol induces dopamine release in the human striatum

1 reference

12 December 2020

Cannabis as a risk factor for psychosis: systematic review

1 reference

12 December 2020

Developing therapeutics for schizophrenia and other psychotic disorders

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12 December 2020

Cannabis-induced psychosis and subsequent schizophrenia-spectrum disorders: follow-up study of 535 incident cases

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12 December 2020

The adolescent brain and age-related behavioral manifestations

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12 December 2020

Chronic (-)-delta9-tetrahydrocannabinol treatment induces sensitization to the psychomotor effects of amphetamine in rats

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12 December 2020

Trends in cannabis use prior to first presentation with schizophrenia, in South-East London between 1965 and 1999.

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12 December 2020

Structure of a cannabinoid receptor and functional expression of the cloned cDNA

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12 December 2020

Neurophysiological studies of sensory gating in rats: effects of amphetamine, phencyclidine, and haloperidol.

1 reference

12 December 2020

Reply to a case report by Ian Sale and Henry Kristall--March issue

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12 December 2020

Adolescent exposure to cannabinoids induces long-lasting changes in the response to drugs of abuse of rat midbrain dopamine neurons

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12 December 2020

Isolation and structure of a brain constituent that binds to the cannabinoid receptor

1 reference

12 December 2020

Psychotic experiences in the general population: a twenty-year prospective community study

1 reference

12 December 2020

Effects of haloperidol on the behavioral, subjective, cognitive, motor, and neuroendocrine effects of Delta-9-tetrahydrocannabinol in humans

1 reference

12 December 2020

Presynaptic specificity of endocannabinoid signaling in the hippocampus

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12 December 2020

Cannabis Psychosis and Paranoid Schizophrenia

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12 December 2020

Schizophrenia: an integrative approach to modelling a complex disorder.

1 reference

12 December 2020

Pain and emotion interactions in subregions of the cingulate gyrus

1 reference

12 December 2020

Immunohistochemical description of the endogenous cannabinoid system in the rat cerebellum and functionally related nuclei

1 reference

12 December 2020

The effects of clozapine on alcohol and drug use disorders among patients with schizophrenia

1 reference

12 December 2020

Cannabis and schizophrenia. A longitudinal study of Swedish conscripts

1 reference

12 December 2020

Antipsychotic-induced alterations in CB1 receptor-mediated G-protein signaling and in vivo pharmacology in rats

1 reference

12 December 2020

Prevalence, correlates, disability, and comorbidity of DSM-IV borderline personality disorder: results from the Wave 2 National Epidemiologic Survey on Alcohol and Related Conditions

1 reference

12 December 2020

The effect of chronic peripubertal cannabinoid treatment on deficient object recognition memory in rats after neonatal mPFC lesion.

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12 December 2020

CNR1, central cannabinoid receptor gene, associated with susceptibility to hebephrenic schizophrenia

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12 December 2020

Anxiolytic-like properties of the anandamide transport inhibitor AM404.

1 reference

12 December 2020

Neurophysiological evidence for a defect in neuronal mechanisms involved in sensory gating in schizophrenia.

1 reference

12 December 2020

Mouse genetic models for prepulse inhibition: an early review

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12 December 2020

Prospective cohort study of cannabis use, predisposition for psychosis, and psychotic symptoms in young people

1 reference

12 December 2020

Epidemiological analysis of alcohol and drug use as risk factors for psychotic experiences

1 reference

12 December 2020

Effect of clozapine on caudate nucleus volume in relation to symptoms of schizophrenia

1 reference

12 December 2020

Endogenous cannabinoids mediate retrograde signalling at hippocampal synapses

1 reference

12 December 2020

The effect of Delta9-tetrahydrocannabinol on sensorimotor gating in socially isolated rats

1 reference

12 December 2020

A review of psychoactive substance use and abuse in schizophrenia. Patterns of drug choice

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12 December 2020

Association of cannabis use with prodromal symptoms of psychosis in adolescence

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12 December 2020

Association of dopamine transporter loss in the orbitofrontal and dorsolateral prefrontal cortices with methamphetamine-related psychiatric symptoms

1 reference

12 December 2020

The cannabinoid receptor: biochemical, anatomical and behavioral characterization

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12 December 2020

Moderation of the effect of adolescent-onset cannabis use on adult psychosis by a functional polymorphism in the catechol-O-methyltransferase gene: longitudinal evidence of a gene X environment interaction

1 reference

12 December 2020

A Novel Missense Mutation in the Transmembrane Domain of Neuregulin 1 is Associated with Schizophrenia

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12 December 2020

Cannabis use and the risk of later schizophrenia: a review

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12 December 2020

10.1007/S00213-009-1612-6

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Dimensions Publication ID

5 August 2017

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