Chemical synthesis and biological characterization of phosphorothioate analogs of 2', 5'-3'-deoxyadenylate trimer (Q34983731)

5 August 2017

title

Chemical synthesis and biological characterization of phosphorothioate analogs of 2', 5'-3'-deoxyadenylate trimer (English)

1 reference

5 August 2017

Sobol RW

1

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5 August 2017

Charubala R

series ordinal

2

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5 August 2017

Pfleiderer W

series ordinal

3

1 reference

5 August 2017

Suhadolnik RJ

series ordinal

4

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5 August 2017

language of work or name

English

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publication date

1 May 1993

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5 August 2017

published in

Nucleic Acids Research

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5 August 2017

volume

21

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5 August 2017

issue

10

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5 August 2017

page(s)

2437-2443

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Synthesis and characterization of (2′-5′)ppp3′dA(p3′dA)n, an analogue of (2′-5′)pppA(pA)n

5 August 2017

cites work

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Enzymatic synthesis of the 2',5'-A4 tetramer analog, 2',5'-ppp3'dA(p3'dA)3, by rabbit reticulocyte lysates: binding and activation of the 2',5'-A eta dependent nuclease, hydrolysis of mRNA, and inhibition of protein synthesis

8 July 2018

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Oligonucleotide structural parameters that influence binding of 5'-O-triphosphoadenylyl-(2'----5')-adenylyl-(2'----5')-adenosine to the 5'-O-triphosphoadenylyl-(2'----5')-adenylyl-(2'----5')-adenosine dependent endoribonuclease: chain length, phosph

8 July 2018

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In situ activation of bis-dialkylaminophosphines--a new method for synthesizing deoxyoligonucleotides on polymer supports.

8 July 2018

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Biochemistry of Interferons and Their Actions

8 July 2018

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Core (2'-5')oligoadenylate and the cordycepin analog: inhibitors of Epstein--Barr virus-induced transformation of human lymphocytes in the absence of interferon

8 July 2018

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Expression of the 2-5A system during the cell cycle.

8 July 2018

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Increased rate of degradation of c-myc mRNA in interferon-treated Daudi cells

8 July 2018

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Interferon regulates c-myc gene expression in Daudi cells at the post-transcriptional level

8 July 2018

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The cordycepin analogue of 2,5A and its threo isomer. Chemical synthesis, conformation and biological activity

8 July 2018

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Phosphorothioate analogues of 2',5'-oligoadenylate. Enzymatic synthesis, properties, and biological activities of 2',5'-phosphorothioates from adenosine 5'-O-(2-thiotriphosphate) and adenosine 5'-O-(3-thiotriphosphate).

8 July 2018

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Phosphorothioate analogues of 2',5'-oligoadenylate. Activation of 2',5'-oligoadenylate-dependent endoribonuclease by 2',5'-phosphorothioate cores and 5'-monophosphates

8 July 2018

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Phosphorothioate analogues of 2',5'-oligoadenylate. Enzymatically synthesized 2',5'-phosphorothioate dimer and trimer: unequivocal structural assignment and activation of 2',5'-oligoadenylate-dependent endoribonuclease

8 July 2018

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Purification and analysis of murine 2-5A-dependent RNase

8 July 2018

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Replacement of the ribofuranose oxygen of 2-5A derivatives by methylene: synthesis of an aristeromycin analogue of 2-5A core 5'-monophosphate (5'-O-phosphoryladenylyl)(2'----5')adenyl(2'----5')adenosine

8 July 2018

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Phosphorothioate and cordycepin analogues of 2',5'-oligoadenylate: inhibition of human immunodeficiency virus type 1 reverse transcriptase and infection in vitro

8 July 2018

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Chemical synthesis and biological activities of analogues of 2',5'-oligoadenylates containing 8-substituted adenosine derivatives

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=309544

Phosphorothioate analogues of (2'-5')(A)4: agonist and antagonist activities in intact cells.

8 July 2018

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Regulation of Viral and Cellular RNA Turnover in Cells Infected by Eukaryotic Viruses including HIV-1

8 July 2018

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Possible involvement of (2'5')oligoadenylate synthetase activity in pre-mRNA splicing

8 July 2018

1 reference

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Cordycepin analogues of 2',5'-oligoadenylate inhibit human immunodeficiency virus infection via inhibition of reverse transcriptase

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=309544

Reduction of N-myc expression by antisense RNA is amplified by interferon: Possible involvement of the 2-5A system

8 July 2018

1 reference

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5'-dephosphorylated 2',5'-adenylate trimer and its analogs. Inhibition of tobacco mosaic virus replication in tobacco mosaic virus-infected leaf discs, protoplasts, and intact tobacco plants.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=309544

Inhibition of Epstein-Barr virus-associated nuclear antigen (EBNA) induction by (2′,5′)oligoadenylate and the cordycepin analog: Mechanism of action for inhibition of EBV-induced transformation

26 October 2018

1 reference

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Interferon action--sequence specificity of the ppp(A2'p)nA-dependent ribonuclease.

26 October 2018

1 reference

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Radioimmune, radiobinding and HPLC analysis of 2-5A and related oligonucleotides from intact cells

26 October 2018

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12 December 2020

Synthesis, characterization and properties of ppp(A2'p)nApCp and related high-specific-activity 32P-labelled derivatives of ppp(A2'p)nA

1 reference

12 December 2020

Interferon Action: RNA Cleavage Pattern of a (2′-5′)Oligoadenylate—Dependent Endonuclease

1 reference

12 December 2020

Analogs of (A2'p)nA. Correlation of structure of analogs of ppp(A2'p)2A and (A2'p)2A with stability and biological activity

1 reference

12 December 2020

Analogues and analogue inhibitors of ppp(A2'p)nA. Their stability and biological activity

1 reference

12 December 2020

Synthesis and biological activity of tubercidin analogues of ppp5'A2'p(5'A2'p)n5'A

1 reference

12 December 2020

Cordycepin analogs of ppp5'A2'p5'A2'p5'A (2-5A) inhibit protein synthesis through activation of the 2-5A-dependent endonuclease

1 reference

12 December 2020

Cell cycle regulation (G1) by autocrine interferon and dissociation between autocrine interferon and 2',5'-oligoadenylate synthetase expression

1 reference

12 December 2020

Identifiers

DOI

10.1093/NAR/21.10.2437

1 reference

5 August 2017

1 reference

5 August 2017

1 reference