Delayed disease onset and extended survival in the SOD1G93A rat model of amyotrophic lateral sclerosis after suppression of mutant SOD1 in the motor cortex (Q34983540)

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English	Delayed disease onset and extended survival in the SOD1G93A rat model of amyotrophic lateral sclerosis after suppression of mutant SOD1 in the motor cortex	scientific article

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scholarly article

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Europe PubMed Central

5 August 2017

Delayed disease onset and extended survival in the SOD1G93A rat model of amyotrophic lateral sclerosis after suppression of mutant SOD1 in the motor cortex (English)

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Europe PubMed Central

5 August 2017

amyotrophic lateral sclerosis

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Genevieve Gowing

2

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9 June 2020

Jean-Philippe Vit

5

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9 June 2020

Laura Ferraiuolo

9

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9 June 2020

11

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9 June 2020

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Gretchen M Thomsen

1

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9 June 2020

Jessica Latter

3

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9 June 2020

Maximus Chen

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9 June 2020

Kevin Staggenborg

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9 June 2020

Pablo Avalos

7

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9 June 2020

Mor Alkaslasi

8

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9 June 2020

Shibi Likhite

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9 June 2020

Clive N Svendsen

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9 June 2020

language of work or name

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publication date

1 November 2014

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Journal of Neuroscience

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9 June 2020

34

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9 June 2020

15587-15600

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9 June 2020

Experimental trials in amyotrophic lateral sclerosis: a review of recently completed, ongoing and planned trials using existing and novel drugs

1 reference

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8 July 2018

Intrinsic membrane hyperexcitability of amyotrophic lateral sclerosis patient-derived motor neurons

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8 July 2018

Amyotrophic lateral sclerosis: a long preclinical period?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4298650

8 July 2018

Microglia induce motor neuron death via the classical NF-κB pathway in amyotrophic lateral sclerosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4298650

8 July 2018

Necroptosis drives motor neuron death in models of both sporadic and familial ALS.

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8 July 2018

Cortical dysfunction underlies the development of the split-hand in amyotrophic lateral sclerosis

1 reference

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8 July 2018

Prion-like activity of Cu/Zn superoxide dismutase: implications for amyotrophic lateral sclerosis.

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8 July 2018

Therapeutic AAV9-mediated suppression of mutant SOD1 slows disease progression and extends survival in models of inherited ALS

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8 July 2018

Converging mechanisms in ALS and FTD: disrupted RNA and protein homeostasis

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8 July 2018

eGFP expression under UCHL1 promoter genetically labels corticospinal motor neurons and a subpopulation of degeneration-resistant spinal motor neurons in an ALS mouse model

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8 July 2018

New considerations in the design of clinical trials for amyotrophic lateral sclerosis

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8 July 2018

AAV2 mediated retrograde transduction of corticospinal motor neurons reveals initial and selective apical dendrite degeneration in ALS.

1 reference

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8 July 2018

Axon degeneration: Molecular mechanisms of a self-destruction pathway

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8 July 2018

The seeds of neurodegeneration: prion-like spreading in ALS

1 reference

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8 July 2018

A hexanucleotide repeat expansion in C9ORF72 is the cause of chromosome 9p21-linked ALS-FTD

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8 July 2018

Expanded GGGGCC hexanucleotide repeat in noncoding region of C9ORF72 causes chromosome 9p-linked FTD and ALS

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8 July 2018

A comparison of in vitro properties of resting SOD1 transgenic microglia reveals evidence of reduced neuroprotective function

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8 July 2018

Astrocytes from familial and sporadic ALS patients are toxic to motor neurons

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8 July 2018

Corticospinal motor neurons and related subcerebral projection neurons undergo early and specific neurodegeneration in hSOD1G⁹³A transgenic ALS mice

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8 July 2018

Neuroinflammation in amyotrophic lateral sclerosis: role of glial activation in motor neuron disease

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8 July 2018

ALS-linked mutant superoxide dismutase 1 (SOD1) alters mitochondrial protein composition and decreases protein import.

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8 July 2018

Deficits in axonal transport precede ALS symptoms in vivo

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8 July 2018

The "dying-back" phenomenon of motor neurons in ALS.

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8 July 2018

Downregulation of genes with a function in axon outgrowth and synapse formation in motor neurones of the VEGFdelta/delta mouse model of amyotrophic lateral sclerosis

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8 July 2018

Axon guidance proteins: novel therapeutic targets for ALS?

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8 July 2018

Human embryonic stem cell-derived motor neurons are sensitive to the toxic effect of glial cells carrying an ALS-causing mutation

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8 July 2018

Transgenics, toxicity and therapeutics in rodent models of mutant SOD1-mediated familial ALS.

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8 July 2018

Efficacy of minocycline in patients with amyotrophic lateral sclerosis: a phase III randomised trial.

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8 July 2018

Sexual dimorphism in disease onset and progression of a rat model of ALS.

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8 July 2018

Gene transfer demonstrates that muscle is not a primary target for non-cell-autonomous toxicity in familial amyotrophic lateral sclerosis

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8 July 2018

The expression of the chemorepellent Semaphorin 3A is selectively induced in terminal Schwann cells of a subset of neuromuscular synapses that display limited anatomical plasticity and enhanced vulnerability in motor neuron disease

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8 July 2018

A mutation in dynein rescues axonal transport defects and extends the life span of ALS mice

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8 July 2018

Virus-delivered small RNA silencing sustains strength in amyotrophic lateral sclerosis

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8 July 2018

Neuronal subtype-specific genes that control corticospinal motor neuron development in vivo

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8 July 2018

Beta-lactam antibiotics offer neuroprotection by increasing glutamate transporter expression.

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8 July 2018

Brainstem substrates of sympatho-motor circuitry identified using trans-synaptic tracing with pseudorabies virus recombinants.

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8 July 2018

Focal loss of the glutamate transporter EAAT2 in a transgenic rat model of SOD1 mutant-mediated amyotrophic lateral sclerosis (ALS).

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8 July 2018

A Ufd2/D4Cole1e chimeric protein and overexpression of Rbp7 in the slow Wallerian degeneration (WldS) mouse

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8 July 2018

Pseudorabies virus expressing enhanced green fluorescent protein: A tool for in vitro electrophysiological analysis of transsynaptically labeled neurons in identified central nervous system circuits.

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8 July 2018

Slowing of axonal transport is a very early event in the toxicity of ALS-linked SOD1 mutants to motor neurons

1 reference

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8 July 2018

Different patterns of neuronal infection after intracerebral injection of two strains of pseudorabies virus

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8 July 2018

Amyotrophic lateral sclerosis: lower motor neuron disease spreading to upper motor neurons

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8 July 2018

Motor neuron degeneration in mice that express a human Cu,Zn superoxide dismutase mutation

1 reference

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8 July 2018

A sensitive and reliable locomotor rating scale for open field testing in rats

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8 July 2018

Axotomy-induced axonal degeneration is mediated by calcium influx through ion-specific channels

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4298650

8 July 2018

Amyotrophic lateral sclerosis (ALS): a phylogenetic disease of the corticomotoneuron?

1 reference

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8 July 2018

Cortical excitability distinguishes ALS from mimic disorders.

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26 October 2018

Functional mapping of the motor cortex of the rat using transdural electrical stimulation.

1 reference

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26 October 2018

Intravascular AAV9 preferentially targets neonatal neurons and adult astrocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4298650

26 October 2018

Cortical hyperexcitability may precede the onset of familial amyotrophic lateral sclerosis.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4298650

26 October 2018

Novel threshold tracking techniques suggest that cortical hyperexcitability is an early feature of motor neuron disease.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4298650

26 October 2018

Silencing mutant SOD1 using RNAi protects against neurodegeneration and extends survival in an ALS model

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4298650

26 October 2018

Lentiviral-mediated silencing of SOD1 through RNA interference retards disease onset and progression in a mouse model of ALS.

1 reference

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26 October 2018

Wild-Type Nonneuronal Cells Extend Survival of SOD1 Mutant Motor Neurons in ALS Mice

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26 October 2018

SOD1 mutants linked to amyotrophic lateral sclerosis selectively inactivate a glial glutamate transporter.

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26 October 2018

Limited corticospinal tract involvement in amyotrophic lateral sclerosis subjects with the A4V mutation in the copper/zinc superoxide dismutase gene.

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26 October 2018

Pseudorabies virus infection of the rat central nervous system: ultrastructural characterization of viral replication, transport, and pathogenesis.

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26 October 2018

Familial ALS with extreme phenotypic variability due to the I113T SOD1 mutation

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9 December 2018

Neuromuscular dysfunction in the mutant superoxide dismutase mouse model of amyotrophic lateral sclerosis

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9 December 2018

Temperature modulation reveals three distinct stages of Wallerian degeneration

1 reference

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Amyotrophic lateral sclerosis is a distal axonopathy: evidence in mice and man

1 reference

https://pubmed.ncbi.nlm.nih.gov/25411487

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Loss of the compound action potential: an electrophysiological, biochemical and morphological study of early events in axonal degeneration in the C57BL/Ola mouse

1 reference

https://pubmed.ncbi.nlm.nih.gov/25411487

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Patterns of Wallerian degeneration of myelinated fibres in short and long peripheral stumps and in isolated segments of rat phrenic nerve. Interpretation of the role of axoplasmic flow of the trophic factor

1 reference

https://pubmed.ncbi.nlm.nih.gov/25411487

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1523/JNEUROSCI.2037-14.2014

1 reference

Europe PubMed Central

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9 June 2020

1 reference

Europe PubMed Central

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9 June 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25411487%20AND%20SRC:MED&resulttype=core&format=json

9 June 2020

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