Transcriptional Factor NF-κB as a Target for Therapy in Parkinson's Disease (Q34983243)

5 August 2017

1 reference

title

Transcriptional Factor NF-κB as a Target for Therapy in Parkinson's Disease (English)

1 reference

5 August 2017

0 references

1 reference

Patrick M Flood

1

1 reference

5 August 2017

Li Qian

2

1 reference

5 August 2017

Lynda J Peterson

3

1 reference

5 August 2017

Feng Zhang

4

1 reference

5 August 2017

Jing-Shan Shi

5

1 reference

5 August 2017

Hui-Ming Gao

6

1 reference

5 August 2017

Jau-Shyong Hong

7

1 reference

5 August 2017

30 March 2011

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5 August 2017

1 reference

5 August 2017

2011

1 reference

5 August 2017

216298

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Creative Commons Attribution 3.0 Unported

5 August 2017

start time

1 January 2011

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

1 reference

April 2022 Public Data File from Crossref

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8 July 2018

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8 July 2018

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8 July 2018

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8 July 2018

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8 July 2018

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8 July 2018

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8 July 2018

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8 July 2018

1 reference

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Selective inhibition of NF-kappa B blocks osteoclastogenesis and prevents inflammatory bone destruction in vivo.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3095232

Inhibitor of kappaB kinase is required to activate a subset of interferon gamma-stimulated genes.

8 July 2018

1 reference

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IkappaB kinase-alpha acts in the epidermis to control skeletal and craniofacial morphogenesis

8 July 2018

1 reference

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Inhibiting cytokines of the interleukin-12 family: recent advances and novel challenges.

8 July 2018

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Time-course of nigrostriatal degeneration in a progressive MPTP-lesioned macaque model of Parkinson's disease

8 July 2018

1 reference

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8 July 2018

1 reference

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Parkinson's disease: mechanisms and models

8 July 2018

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Histone H3 phosphorylation by IKK-alpha is critical for cytokine-induced gene expression

8 July 2018

1 reference

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The p65/RelA subunit of NF-kappaB suppresses the sustained, antiapoptotic activity of Jun kinase induced by tumor necrosis factor

8 July 2018

1 reference

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Interleukin-10 in the brain.

8 July 2018

1 reference

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NF-kappa B as a therapeutic target in multiple myeloma

8 July 2018

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NF-kappaB in transplantation: friend or foe?

8 July 2018

1 reference

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Microglial chemotaxis, activation, and phagocytosis of amyloid beta-peptide as linked phenomena in Alzheimer's disease

8 July 2018

1 reference

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Mesodermal patterning defect in mice lacking the Ste20 NCK interacting kinase (NIK).

8 July 2018

1 reference

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Interleukin-10 and the interleukin-10 receptor

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3095232

Changes in cytokines and neurotrophins in Parkinson's disease

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3095232

NF-kappaB: a key role in inflammatory diseases

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3095232

Selective inhibition of NF-kappaB activation by a peptide that blocks the interaction of NEMO with the IkappaB kinase complex

8 July 2018

1 reference

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Severe liver degeneration and lack of NF-kappaB activation in NEMO/IKKgamma-deficient mice

8 July 2018

1 reference

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Regulation of interleukin-8 gene expression

8 July 2018

1 reference

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Stimulus-specific regulation of chemokine expression involves differential activation of the redox-responsive transcription factors AP-1 and NF-kappaB.

8 July 2018

1 reference

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Oxidative mechanisms in nigral cell death in Parkinson's disease.

8 July 2018

1 reference

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RelB regulation of chemokine expression modulates local inflammation.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3095232

Nuclear translocation of NF-kappaB is increased in dopaminergic neurons of patients with parkinson disease

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3095232

Molecular mechanisms of microglial activation

8 July 2018

1 reference

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Transcriptional regulation of endothelial cell adhesion molecules: a dominant role for NF-kappa B.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3095232

Reactive microglia are positive for HLA-DR in the substantia nigra of Parkinson's and Alzheimer's disease brains

8 July 2018

1 reference

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Inducibility of kappa immunoglobulin enhancer-binding protein Nf-kappa B by a posttranslational mechanism

8 July 2018

1 reference

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Multiple nuclear factors interact with the immunoglobulin enhancer sequences

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3095232

Glutamate neurotoxicity and diseases of the nervous system

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3095232

Presence of reactive microglia in monkey substantia nigra years after 1‐methyl‐4‐phenyl‐1,2,3,6‐tetrahydropyridine administration

8 July 2018

1 reference

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Neuroinflammation of the nigrostriatal pathway during progressive 6-OHDA dopamine degeneration in rats monitored by immunohistochemistry and PET imaging.

21 January 2018

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https://api.crossref.org/works/10.4061%2F2011%2F216298

Progressive degeneration of dopamine neurons in 6-hydroxydopamine rat model of Parkinson's disease does not involve activation of caspase-9 and caspase-3.

21 January 2018

1 reference

https://api.crossref.org/works/10.4061%2F2011%2F216298

Tumor necrosis factor-alpha (TNF-alpha) increases both in the brain and in the cerebrospinal fluid from parkinsonian patients.

21 January 2018

1 reference

https://api.crossref.org/works/10.4061%2F2011%2F216298

Neurotoxic effects of lipopolysaccharide on nigral dopaminergic neurons are mediated by microglial activation, interleukin-1beta, and expression of caspase-11 in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.4061%2F2011%2F216298

Distribution of major histocompatibility complex class II-positive microglia and cytokine profile of Parkinson's disease brains

21 January 2018

1 reference

https://api.crossref.org/works/10.4061%2F2011%2F216298

Increased plasma levels of TNF-alpha but not of IL1-beta in MPTP-treated monkeys one year after the MPTP administration.

21 January 2018

1 reference

https://api.crossref.org/works/10.4061%2F2011%2F216298

Characterization of the Ikappa B-kinase NEMO binding domain

21 January 2018

1 reference

https://api.crossref.org/works/10.4061%2F2011%2F216298

Distinct roles of the Ikappa B kinase alpha and beta subunits in liberating nuclear factor kappa B (NF-kappa B) from Ikappa B and in phosphorylating the p65 subunit of NF-kappa B.

21 January 2018

1 reference

https://api.crossref.org/works/10.4061%2F2011%2F216298

Two pathways to NF-kappaB.

21 January 2018

1 reference

https://api.crossref.org/works/10.4061%2F2011%2F216298

A nucleosomal function for IkappaB kinase-alpha in NF-kappaB-dependent gene expression

21 January 2018

1 reference

https://api.crossref.org/works/10.4061%2F2011%2F216298

p53 protein, interferon-gamma, and NF-kappaB levels are elevated in the parkinsonian brain.

21 January 2018

1 reference

https://api.crossref.org/works/10.4061%2F2011%2F216298

Amelioration of acute inflammation by systemic administration of a cell-permeable peptide inhibitor of NF-kappaB activation.

21 January 2018

1 reference

https://api.crossref.org/works/10.4061%2F2011%2F216298

Neuroprotective potential of the NF-κB inhibitor peptide IKK-NBD in cerebral ischemia-reperfusion injury.

21 January 2018

1 reference

https://api.crossref.org/works/10.4061%2F2011%2F216298

The I{kappa}B kinase inhibitor nuclear factor-{kappa}B essential modulator-binding domain peptide for inhibition of injury-induced neointimal formation.

21 January 2018

1 reference

https://api.crossref.org/works/10.4061%2F2011%2F216298

Attenuation of murine collagen-induced arthritis by a novel, potent, selective small molecule inhibitor of IkappaB Kinase 2, TPCA-1 (2-[(aminocarbonyl)amino]-5-(4-fluorophenyl)-3-thiophenecarboxamide), occurs via reduction of proinflammatory cytokin

21 January 2018

1 reference

https://api.crossref.org/works/10.4061%2F2011%2F216298

Epicutaneously induced TGF-beta-dependent tolerance inhibits experimental autoimmune encephalomyelitis.

21 January 2018

1 reference

https://api.crossref.org/works/10.4061%2F2011%2F216298

NADPH oxidase inhibitor DPI is neuroprotective at femtomolar concentrations through inhibition of microglia over-activation.

21 January 2018

1 reference

https://api.crossref.org/works/10.4061%2F2011%2F216298

Curcumin protects dopaminergic neuron against LPS induced neurotoxicity in primary rat neuron/glia culture.

21 January 2018

1 reference

https://api.crossref.org/works/10.4061%2F2011%2F216298

IL-8 induces expression of matrix metalloproteinases, cell cycle and pro-apoptotic proteins, and cell death in cultured neurons.

21 January 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3095232

Transforming growth factor-beta 1 increases bad phosphorylation and protects neurons against damage.

26 October 2018

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Normal epidermal differentiation but impaired skin-barrier formation upon keratinocyte-restricted IKK1 ablation

26 October 2018

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12 December 2020

Nitric oxide synthase and neuronal vulnerability in Parkinson's disease.

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12 December 2020

The IkappaB kinase (IKK) inhibitor, NEMO-binding domain peptide, blocks osteoclastogenesis and bone erosion in inflammatory arthritis

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12 December 2020

Increased cerebrospinal fluid concentration of nitrite in Parkinson's disease

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12 December 2020

Interleukin-1 beta, interleukin-6, epidermal growth factor and transforming growth factor-alpha are elevated in the brain from parkinsonian patients

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12 December 2020

Effects of enhanced striatal dopamine turnover in vivo on glutathione oxidation

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12 December 2020

Neuroinflammatory processes in Parkinson's disease

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12 December 2020

IKKbeta inhibition attenuates myocardial injury and dysfunction following acute ischemia-reperfusion injury

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12 December 2020

Role of NF-κB in transcriptional regulation of the phagocyte NADPH oxidase by tumor necrosis factor-α

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12 December 2020

Identifiers

DOI

10.4061/2011/216298

1 reference

5 August 2017

1 reference

5 August 2017

1 reference