Gene therapy with tumor-specific promoter mediated suicide gene plus IL-12 gene enhanced tumor inhibition and prolonged host survival in a murine model of Lewis lung carcinoma (Q34980275)

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English	Gene therapy with tumor-specific promoter mediated suicide gene plus IL-12 gene enhanced tumor inhibition and prolonged host survival in a murine model of Lewis lung carcinoma	scientific article

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scholarly article

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Europe PubMed Central

5 August 2017

Gene therapy with tumor-specific promoter mediated suicide gene plus IL-12 gene enhanced tumor inhibition and prolonged host survival in a murine model of Lewis lung carcinoma (English)

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Europe PubMed Central

5 August 2017

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author name string

Yu Xu

1

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Europe PubMed Central

5 August 2017

Jinxuan Hou

2

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Europe PubMed Central

5 August 2017

Zhengchun Liu

3

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Europe PubMed Central

5 August 2017

Haijun Yu

4

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Europe PubMed Central

5 August 2017

Wenjie Sun

5

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Europe PubMed Central

5 August 2017

Jie Xiong

6

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Europe PubMed Central

5 August 2017

Zhengkai Liao

7

1 reference

Europe PubMed Central

5 August 2017

Fuxiang Zhou

8

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Europe PubMed Central

5 August 2017

Conghua Xie

9

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Europe PubMed Central

5 August 2017

Yunfeng Zhou

10

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Europe PubMed Central

5 August 2017

publication date

11 April 2011

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Europe PubMed Central

5 August 2017

Journal of Translational Medicine

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Europe PubMed Central

5 August 2017

9

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Europe PubMed Central

5 August 2017

39

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Europe PubMed Central

5 August 2017

https://scigraph.springernature.com/pub.10.1186/1479-5876-9-39

0 references

Targeted killing effects of double CD and TK suicide genes controlled by survivin promoter on gastric cancer cell

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Adenovirus-mediated cancer gene therapy and virotherapy (Review).

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Experimental strategies in gene therapy of cancer.

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New strategies for cancer gene therapy: progress and opportunities

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8 July 2018

Radiation enhances suicide gene therapy in radioresistant laryngeal squamous cell carcinoma via activation of a tumor-specific promoter

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8 July 2018

Advances in interleukin-12 gene therapy for acquired liver diseases

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Targeting gene therapy for hepatocarcinoma cells with the E. coli purine nucleoside phosphorylase suicide gene system directed by a chimeric alpha-fetoprotein promoter.

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Radio-activation of hTERT promoter in larynx squamous carcinoma cells: an 'indirected-activator' strategy in radio-gene-therapy.

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Combined GM-CSF and IL-12 gene therapy synergistically suppresses the growth of orthotopic liver tumors.

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Combination of cytosine deaminase with uracil phosphoribosyl transferase leads to local and distant bystander effects against RM1 prostate cancer in mice.

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Telomerase-dependent gene therapy

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8 July 2018

Adenovirus-mediated tumor-specific combined gene therapy using Herpes simplex virus thymidine/ganciclovir system and murine interleukin-12 induces effective antitumor activity against medullary thyroid carcinoma

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8 July 2018

hTERT promoter induces tumor-specific Bax gene expression and cell killing in syngenic mouse tumor model and prevents systemic toxicity

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8 July 2018

Approaches to gene-directed enzyme prodrug therapy (GDEPT).

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Prostate-specific antigen promoter/enhancer driven gene therapy for prostate cancer: construction and testing of a tissue-specific adenovirus vector.

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8 July 2018

The human telomerase catalytic subunit hTERT: organization of the gene and characterization of the promoter

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Toward targeted "oxidation therapy" of cancer: peroxidase-catalysed cytotoxicity of indole-3-acetic acids

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A survey of telomerase activity in human cancer

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Gap junction function and cancer.

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8 July 2018

Tumorigenicity of mouse T lymphoma cells is controlled by the level of major histocompatibility complex class I H-2Kk antigens

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Specific association of human telomerase activity with immortal cells and cancer

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A novel telomerase-specific gene therapy: gene transfer of caspase-8 utilizing the human telomerase catalytic subunit gene promoter

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21 January 2018

Mechanisms of cytotoxicity induced by horseradish peroxidase/indole-3-acetic acid gene therapy

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Development of a novel enzyme/prodrug combination for gene therapy of cancer: horseradish peroxidase/indole-3-acetic acid

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21 January 2018

Combination suicide/cytokine gene therapy as adjuvants to a defective herpes simplex virus-based cancer vaccine.

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Immune system in suicide-gene therapy

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Cytokine gene therapy of cancer using gene gun technology: superior antitumor activity of interleukin-12.

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Evaluation of the antitumoral effect mediated by IL-12 and HSV-tk genes when delivered by a novel lipid-based system

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21 January 2018

Combination gene therapy with adenoviral vector-mediated HSV-tk+GCV and IL-12 in an orthotopic mouse model for prostate cancer

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21 January 2018

Adenoviral herpes simplex virus thymidine kinase gene therapy in an orthotopic lung cancer model

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Tumor-specific transgene expression from the human telomerase reverse transcriptase promoter enables targeting of the therapeutic effects of the Bax gene to cancers.

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26 October 2018

Cloning and characterization of the promoter region of human telomerase reverse transcriptase gene.

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26 October 2018

Amount of interleukin 12 available at the tumor site is critical for tumor regression.

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Cloning of human telomerase catalytic subunit (hTERT) gene promoter and identification of proximal core promoter sequences essential for transcriptional activation in immortalized and cancer cells

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12 December 2020

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10.1186/1479-5876-9-39

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Europe PubMed Central

5 August 2017

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Europe PubMed Central

5 August 2017

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Europe PubMed Central

5 August 2017

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