Cytokine detection by ELISPOT: relevance for immunological studies in type 1 diabetes (Q34979245)

5 August 2017

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title

Cytokine detection by ELISPOT: relevance for immunological studies in type 1 diabetes (English)

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5 August 2017

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Guido Meierhoff

1

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5 August 2017

Patrick A Ott

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2

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5 August 2017

Paul V Lehmann

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3

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5 August 2017

Nanette C Schloot

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4

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5 August 2017

1 September 2002

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Diabetes - Metabolism: Research and Reviews

5 August 2017

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5 August 2017

18

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5 August 2017

5

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5 August 2017

367-380

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Immune markers for monitoring the progression of autoimmune disease

5 August 2017

1 reference

Immunoregulatory and cytokine imbalances in the pathogenesis of IDDM. Therapeutic intervention by immunostimulation?

21 January 2018

1 reference

In vivo activity and in vitro specificity of CD4+ Th1 and Th2 cells derived from the spleens of diabetic NOD mice

21 January 2018

1 reference

Identification of naturally processed T cell epitopes from glutamic acid decarboxylase presented in the context of HLA-DR alleles by T lymphocytes of recent onset IDDM patients

21 January 2018

1 reference

Systemic bias of cytokine production toward cell-mediated immune regulation in IDDM and toward humoral immunity in Graves' disease.

21 January 2018

1 reference

Cloned T cells from a recent onset IDDM patient reactive with insulin B-chain.

21 January 2018

1 reference

Auto- and alloimmune reactivity to human islet allografts transplanted into type 1 diabetic patients.

21 January 2018

1 reference

Cytokine-driven proliferation and differentiation of human naive, central memory, and effector memory CD4(+) T cells.

21 January 2018

1 reference

Autoreactive T cell responses in insulin-dependent (Type 1) diabetes mellitus. Report of the first international workshop for standardization of T cell assays

21 January 2018

1 reference

Rapid effector function in CD8+ memory T cells

21 January 2018

1 reference

Enzyme-linked immunosorbent assay (ELISA) quantitative assay of immunoglobulin G

21 January 2018

1 reference

Extreme Th1 bias of invariant Valpha24JalphaQ T cells in type 1 diabetes.

21 January 2018

1 reference

Heterophile antibodies segregate in families and are associated with protection from type 1 diabetes

21 January 2018

1 reference

Heterophile anti-mouse immunoglobulin antibodies may interfere with cytokine measurements in patients with HLA alleles protective for type 1A diabetes

21 January 2018

1 reference

Linear loss of insulin secretory capacity during the last six months preceding IDDM. No effect of antiedematous therapy with ketotifen.

21 January 2018

1 reference

Adipose expression of tumor necrosis factor-alpha: direct role in obesity-linked insulin resistance

21 January 2018

1 reference

Tumour necrosis factor-alpha gene promoter polymorphism and decreased insulin resistance

21 January 2018

1 reference

NIDDM as a disease of the innate immune system: association of acute-phase reactants and interleukin-6 with metabolic syndrome X.

21 January 2018

1 reference

A solid-phase enzyme-linked immunospot (ELISPOT) assay for enumeration of specific antibody-secreting cells

21 January 2018

1 reference

Direct visualization of cytokine-producing recall antigen-specific CD4 memory T cells in healthy individuals and HIV patients.

21 January 2018

1 reference

A T cell clone's avidity is a function of its activation state

21 January 2018

1 reference

Immunomodulatory effect of extracorporeal photopheresis after successful treatment of resistant renal allograft rejection

21 January 2018

1 reference

Enzyme-linked immunosorbent assay spot detection of interferon-gamma and interleukin 5-producing cells as a predictive marker for renal allograft failure

21 January 2018

1 reference

Beta-cell function in new-onset type 1 diabetes and immunomodulation with a heat-shock protein peptide (DiaPep277): a randomised, double-blind, phase II trial

21 January 2018

1 reference

A disease-associated cellular immune response in type 1 diabetics to an immunodominant epitope of insulin

21 January 2018

1 reference

Characterization of preparations of GAD65, proinsulin, and the islet tyrosine phosphatase IA-2 for use in detection of autoreactive T-cells in type 1 diabetes: report of phase II of the Second International Immunology of Diabetes Society Workshop fo

21 January 2018

1 reference

Ex vivo IFN-gamma secretion by circulating CD8 T lymphocytes: implications of a novel approach for T cell monitoring in infectious and malignant diseases.

21 January 2018

1 reference

Cytotoxic T-cell memory without antigen

21 January 2018

1 reference

Enumeration of IFN-gamma-producing cells by flow cytometry. Comparison with fluorescence microscopy

21 January 2018

1 reference

Detection of intracytoplasmic cytokine using flow cytometry and directly conjugated anti-cytokine antibodies.

21 January 2018

1 reference

11-color, 13-parameter flow cytometry: identification of human naive T cells by phenotype, function, and T-cell receptor diversity

21 January 2018

1 reference

A practical approach to multicolor flow cytometry for immunophenotyping

21 January 2018

1 reference

Clonotypic structure of the human CD4+ memory T cell response to cytomegalovirus

21 January 2018

1 reference

Phenotypic analysis of antigen-specific T lymphocytes

21 January 2018

1 reference

T-cell clonality in immune responses

21 January 2018

1 reference

Treatment of multiple sclerosis with Copaxone (COP): Elispot assay detects COP-induced interleukin-4 and interferon-gamma response in blood cells

21 January 2018

1 reference

Cytofluorometric methods for assessing absolute numbers of cell subsets in blood. European Working Group on Clinical Cell Analysis.

21 January 2018

1 reference

Reverse ELISPOT assay for clonal analysis of cytokine production I. Enumeration of gamma-interferon-secreting cells

21 January 2018

1 reference

Th1-like dominance in high-risk first-degree relatives of Type I diabetic patients

21 January 2018

1 reference

A comparison between ELISPOT methods for the detection of cytokine producing cells: greater sensitivity and specificity using ELISA plates as compared to nitrocellulose membranes

21 January 2018

1 reference

Erratum: Extreme Th1 bias of invariant Vα24JαQ T cells in type 1 diabetes

21 January 2018

1 reference

Combined analysis of autoantibodies improves prediction of IDDM in islet cell antibody-positive relatives

21 January 2018

1 reference

Combined use of autoantibodies (IA-2 autoantibody, GAD autoantibody, insulin autoantibody, cytoplasmic islet cell antibodies) in type 1 diabetes: Combinatorial Islet Autoantibody Workshop

21 January 2018

1 reference

Autoantibody appearance and risk for development of childhood diabetes in offspring of parents with type 1 diabetes: the 2-year analysis of the German BABYDIAB Study

21 January 2018

1 reference

Islet antigen-specific T cell clones in autoimmune diabetes: from mice to men.

21 January 2018

1 reference

Transfer of diabetes type 1 by bone-marrow transplantation

21 January 2018

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Development of type 1 diabetes despite severe hereditary B-cell deficiency

21 January 2018

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Benign versus destructive insulitis.

21 January 2018

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Cyclophosphamide treatment of female non-obese diabetic mice causes enhanced expression of inducible nitric oxide synthase and interferon-gamma, but not of interleukin-4

21 January 2018

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T helper cell subsets in insulin-dependent diabetes

21 January 2018

1 reference

Th1-like cytokine production profile and individual specific alterations in TCRBV-gene usage of T cells from newly diagnosed type 1 diabetes patients after stimulation with beta-cell antigens

21 January 2018

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T-cell markers in type I diabetes: progress, prospects and realistic expectations

21 January 2018

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Serum levels of the interferon-gamma-inducing cytokine interleukin-18 are increased in individuals at high risk of developing type I diabetes

21 January 2018

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Increased interleukin-12 plasma concentrations in both, insulin-dependent and non-insulin-dependent diabetes mellitus

21 January 2018

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Elevated serum IP-10 levels observed in type 1 diabetes

21 January 2018

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Serum interleukin-8 level is increased in diabetic patients

21 January 2018

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Serum IFN-gamma and IL-10 levels are associated with disease progression in non-obese diabetic mice

21 January 2018

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Single-cytokine-producing CD4 memory cells predominate in type 1 and type 2 immunity

21 January 2018

1 reference

A sensitive ELISPOT assay to detect low-frequency human T lymphocytes

21 January 2018

1 reference

Assessment of the inhibitory effect of immunosuppressive agents on rat T cell interferon-gamma production using an ELISPOT assay

21 January 2018

1 reference

Pulmonary mononuclear cell responses to antigens of Mycobacterium tuberculosis in healthy household contacts of patients with active tuberculosis and healthy controls from the community

21 January 2018

1 reference

Quantification of self-recognition in multiple sclerosis by single-cell analysis of cytokine production

21 January 2018

1 reference

Increased reactivity to myelin oligodendrocyte glycoprotein peptides and epitope mapping in HLA DR2(15)+ multiple sclerosis

21 January 2018

1 reference

Islet T cells secreting IFN-gamma in NOD mouse diabetes: arrest by p277 peptide treatment

21 January 2018

1 reference

A valid ELISPOT assay for enumeration of ex vivo, antigen-specific, IFNgamma-producing T cells

21 January 2018

1 reference

Quantification of natural antibody producing B cells in rats by an improved ELISPOT technique using the polyvinylidene difluoride membrane as the solid support

21 January 2018

1 reference

In vivo dynamics of anti-viral CD8 T cell responses to different epitopes. An evaluation of bystander activation in primary and secondary responses to viral infection

21 January 2018

1 reference

Status quo in flow-through cytometry

21 January 2018

1 reference

Cy7PE and Cy7APC: bright new probes for immunofluorescence

21 January 2018

1 reference

Cytokine secretion patterns in twins discordant for Type I diabetes

21 January 2018

1 reference

Enumeration of lymphokine-secreting cells as a quantitative measure for cellular immune responses in rhesus macaques.

21 January 2018

1 reference

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Identifiers

DOI

10.1002/DMRR.320

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5 August 2017

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