Super-resolution imaging reveals that loss of the C-terminus of connexin43 limits microtubule plus-end capture and NaV1.5 localization at the intercalated disc. (Q34974501)

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English	Super-resolution imaging reveals that loss of the C-terminus of connexin43 limits microtubule plus-end capture and NaV1.5 localization at the intercalated disc.	scientific article

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13 March 2020

Super-resolution imaging reveals that loss of the C-terminus of connexin43 limits microtubule plus-end capture and NaV1.5 localization at the intercalated disc (English)

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13 March 2020

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13 March 2020

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Anna Pfenniger

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Esperanza Agullo-Pascual

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13 March 2020

Xianming Lin

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13 March 2020

Alejandra Leo-Macias

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13 March 2020

Mingliang Zhang

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13 March 2020

Feng-Xia Liang

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13 March 2020

Zhen Li

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13 March 2020

Indra Lübkemeier

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13 March 2020

Sarah Keegan

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13 March 2020

Klaus Willecke

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18 August 2014

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13 March 2020

Cardiovascular Research

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13 March 2020

104

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13 March 2020

2

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13 March 2020

371-381

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13 March 2020

Arrhythmogenic cardiomyopathy and Brugada syndrome: diseases of the connexome

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8 July 2018

Missense mutations in plakophilin-2 cause sodium current deficit and associate with a Brugada syndrome phenotype

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8 July 2018

Microtubules that form the stationary lattice of muscle fibers are dynamic and nucleated at Golgi elements.

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8 July 2018

Super-resolution fluorescence microscopy of the cardiac connexome reveals plakophilin-2 inside the connexin43 plaque

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4296112

8 July 2018

EB1 levels are elevated in ascorbic Acid (AA)-stimulated osteoblasts and mediate cell-cell adhesion-induced osteoblast differentiation

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8 July 2018

Deletion of the last five C-terminal amino acid residues of connexin43 leads to lethal ventricular arrhythmias in mice without affecting coupling via gap junction channels

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8 July 2018

Super-resolution scanning patch clamp reveals clustering of functional ion channels in adult ventricular myocyte.

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8 July 2018

Microtubule plus-ends within a mitotic cell are 'moving platforms' with anchoring, signalling and force-coupling roles.

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8 July 2018

Cx43 associates with Na(v)1.5 in the cardiomyocyte perinexus.

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4296112

8 July 2018

Loss of αT-catenin alters the hybrid adhering junctions in the heart and leads to dilated cardiomyopathy and ventricular arrhythmia following acute ischemia

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8 July 2018

Computational modeling of axonal microtubule bundles under tension.

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4296112

8 July 2018

Connexin43 ablation in foetal atrial myocytes decreases electrical coupling, partner connexins, and sodium current

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4296112

8 July 2018

Reduced heterogeneous expression of Cx43 results in decreased Nav1.5 expression and reduced sodium current that accounts for arrhythmia vulnerability in conditional Cx43 knockout mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4296112

8 July 2018

Connexin43 and the regulation of intercalated disc function

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4296112

8 July 2018

Connexin43 modulates cell polarity and directional cell migration by regulating microtubule dynamics

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4296112

8 July 2018

Subcellular heterogeneity of sodium current properties in adult cardiac ventricular myocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4296112

8 July 2018

Interactions between ankyrin-G, Plakophilin-2, and Connexin43 at the cardiac intercalated disc

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4296112

8 July 2018

End-binding proteins EB3 and EB1 link microtubules to ankyrin G in the axon initial segment

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4296112

8 July 2018

Connexin 43 connexon to gap junction transition is regulated by zonula occludens-1.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4296112

8 July 2018

SAP97 and dystrophin macromolecular complexes determine two pools of cardiac sodium channels Nav1.5 in cardiomyocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4296112

8 July 2018

The cardiac desmosome and arrhythmogenic cardiomyopathies: from gene to disease.

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8 July 2018

Tubulin polymerization modifies cardiac sodium channel expression and gating

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4296112

8 July 2018

Microtubule plus-end and minus-end capture at adherens junctions is involved in the assembly of apico-basal arrays in polarised epithelial cells

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4296112

8 July 2018

Microtubule assembly, organization and dynamics in axons and dendrites

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8 July 2018

Voltage-gated Nav channel targeting in the heart requires an ankyrin-G dependent cellular pathway

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8 July 2018

Three-dimensional super-resolution imaging by stochastic optical reconstruction microscopy

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8 July 2018

Electrical remodeling contributes to complex tachyarrhythmias in connexin43-deficient mouse hearts

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8 July 2018

Microtubule plus-end-tracking proteins target gap junctions directly from the cell interior to adherens junctions

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4296112

8 July 2018

The area composita of adhering junctions connecting heart muscle cells of vertebrates. I. Molecular definition in intercalated disks of cardiomyocytes by immunoelectron microscopy of desmosomal proteins

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8 July 2018

Zonula occludens-1 alters connexin43 gap junction size and organization by influencing channel accretion

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8 July 2018

Modulation of cardiac gap junction expression and arrhythmic susceptibility.

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8 July 2018

Structural changes in the carboxyl terminus of the gap junction protein connexin43 indicates signaling between binding domains for c-Src and zonula occludens-1

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4296112

8 July 2018

Gap junction protein connexin-43 interacts directly with microtubules

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4296112

8 July 2018

Conduction slowing and sudden arrhythmic death in mice with cardiac-restricted inactivation of connexin43

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8 July 2018

High-resolution model of the microtubule

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8 July 2018

AnkyrinG is required for clustering of voltage-gated Na channels at axon initial segments and for normal action potential firing

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8 July 2018

Gap junction remodeling and spironolactone-dependent reverse remodeling in the hypertrophied heart.

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21 January 2018

C-terminal truncation of connexin43 changes number, size, and localization of cardiac gap junction plaques

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21 January 2018

Microtubules and caliber of central and peripheral processes of sensory axons

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12 December 2020

based on heuristic

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Spatiotemporal development and distribution of intercellular junctions in adult rat cardiomyocytes in culture

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Dynamic changes in conduction velocity and gap junction properties during development of pacing-induced heart failure

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12 December 2020

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Identifiers

10.1093/CVR/CVU195

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13 March 2020

1 reference

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13 March 2020

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13 March 2020

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