Hepatitis C: molecular virology and antiviral targets (Q34970582)

5 August 2017

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title

Hepatitis C: molecular virology and antiviral targets (English)

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5 August 2017

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Darius Moradpour

1

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author name string

Volker Brass

2

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5 August 2017

Rainer Gosert

3

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5 August 2017

Benno Wölk

4

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5 August 2017

Hubert E Blum

5

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5 August 2017

1 October 2002

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Trends in Molecular Medicine

5 August 2017

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5 August 2017

8

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5 August 2017

10

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5 August 2017

476-482

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Hepatitis C virus infection

5 August 2017

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https://api.crossref.org/works/10.1016%2FS1471-4914%2802%2902395-X

7 January 2021

Pathogenesis of chronic hepatitis C: immunological features of hepatic injury and viral persistence.

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2802%2902395-X

7 January 2021

Peginterferon alfa-2b plus ribavirin compared with interferon alfa-2b plus ribavirin for initial treatment of chronic hepatitis C: a randomised trial

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https://api.crossref.org/works/10.1016%2FS1471-4914%2802%2902395-X

7 January 2021

Surprisingly small effect of antiviral treatment in patients with hepatitis C.

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https://api.crossref.org/works/10.1016%2FS1471-4914%2802%2902395-X

7 January 2021

Modeling the hepatitis C virus epidemic in France using the temporal pattern of hepatocellular carcinoma deaths

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https://api.crossref.org/works/10.1016%2FS1471-4914%2802%2902395-X

7 January 2021

Isolation of a cDNA clone derived from a blood-borne non-A, non-B viral hepatitis genome

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https://api.crossref.org/works/10.1016%2FS1471-4914%2802%2902395-X

7 January 2021

An assay for circulating antibodies to a major etiologic virus of human non-A, non-B hepatitis

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https://api.crossref.org/works/10.1016%2FS1471-4914%2802%2902395-X

7 January 2021

Transmission of hepatitis C by intrahepatic inoculation with transcribed RNA

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https://api.crossref.org/works/10.1016%2FS1471-4914%2802%2902395-X

7 January 2021

Replication of subgenomic hepatitis C virus RNAs in a hepatoma cell line

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https://api.crossref.org/works/10.1016%2FS1471-4914%2802%2902395-X

7 January 2021

Replication of hepatitis C virus

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https://api.crossref.org/works/10.1016%2FS1471-4914%2802%2902395-X

7 January 2021

Advances in model systems for hepatitis C virus research

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https://api.crossref.org/works/10.1016%2FS1471-4914%2802%2902395-X

7 January 2021

Hepatitis C virus IRES RNA-induced changes in the conformation of the 40s ribosomal subunit

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https://api.crossref.org/works/10.1016%2FS1471-4914%2802%2902395-X

7 January 2021

Genetic Analysis of Sequences in the 3' Nontranslated Region of Hepatitis C Virus That Are Important for RNA Replication

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https://api.crossref.org/works/10.1016%2FS1471-4914%2802%2902395-X

7 January 2021

Properties of the hepatitis C virus core protein: a structural protein that modulates cellular processes

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https://api.crossref.org/works/10.1016%2FS1471-4914%2802%2902395-X

7 January 2021

Biogenesis of hepatitis C virus envelope glycoproteins

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https://api.crossref.org/works/10.1016%2FS1471-4914%2802%2902395-X

7 January 2021

A model for the hepatitis C virus envelope glycoprotein E2.

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https://api.crossref.org/works/10.1016%2FS1471-4914%2802%2902395-X

7 January 2021

Subcellular Localization and Topology of the p7 Polypeptide of Hepatitis C Virus

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https://api.crossref.org/works/10.1016%2FS1471-4914%2802%2902395-X

7 January 2021

E2-p7 region of the bovine viral diarrhea virus polyprotein: processing and functional studies

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https://api.crossref.org/works/10.1016%2FS1471-4914%2802%2902395-X

7 January 2021

Evidence for a new hepatitis C virus antigen encoded in an overlapping reading frame

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https://api.crossref.org/works/10.1016%2FS1471-4914%2802%2902395-X

7 January 2021

Synthesis of a novel hepatitis C virus protein by ribosomal frameshift

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https://api.crossref.org/works/10.1016%2FS1471-4914%2802%2902395-X

7 January 2021

Alternate translation occurs within the core coding region of the hepatitis C viral genome

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https://api.crossref.org/works/10.1016%2FS1471-4914%2802%2902395-X

7 January 2021

Hepatitis C virus-like particle morphogenesis

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https://api.crossref.org/works/10.1016%2FS1471-4914%2802%2902395-X

7 January 2021

Persistent and transient replication of full-length hepatitis C virus genomes in cell culture

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https://api.crossref.org/works/10.1016%2FS1471-4914%2802%2902395-X

7 January 2021

Structure of dengue virus: implications for flavivirus organization, maturation, and fusion

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https://api.crossref.org/works/10.1016%2FS1471-4914%2802%2902395-X

7 January 2021

CD81 extracellular domain 3D structure: insight into the tetraspanin superfamily structural motifs.

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https://api.crossref.org/works/10.1016%2FS1471-4914%2802%2902395-X

7 January 2021

Binding of hepatitis C virus to CD81

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https://api.crossref.org/works/10.1016%2FS1471-4914%2802%2902395-X

7 January 2021

Hepatitis C virus and other flaviviridae viruses enter cells via low density lipoprotein receptor

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https://api.crossref.org/works/10.1016%2FS1471-4914%2802%2902395-X

7 January 2021

Characterization of hepatitis C virus (HCV) and HCV E2 interactions with CD81 and the low-density lipoprotein receptor

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https://api.crossref.org/works/10.1016%2FS1471-4914%2802%2902395-X

7 January 2021

Binding of hepatitis C virus E2 glycoprotein to CD81 does not correlate with species permissiveness to infection

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https://api.crossref.org/works/10.1016%2FS1471-4914%2802%2902395-X

7 January 2021

Binding of the Hepatitis C Virus Envelope Protein E2 to CD81 Inhibits Natural Killer Cell Functions

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https://api.crossref.org/works/10.1016%2FS1471-4914%2802%2902395-X

7 January 2021

Inhibition of Natural Killer Cells through Engagement of CD81 by the Major Hepatitis C Virus Envelope Protein

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https://api.crossref.org/works/10.1016%2FS1471-4914%2802%2902395-X

7 January 2021

Characterization of Low- and Very-Low-Density Hepatitis C Virus RNA-Containing Particles

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https://api.crossref.org/works/10.1016%2FS1471-4914%2802%2902395-X

7 January 2021

Hepatitis C virus-encoded enzymatic activities and conserved RNA elements in the 3' nontranslated region are essential for virus replication in vivo

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https://api.crossref.org/works/10.1016%2FS1471-4914%2802%2902395-X

7 January 2021

Characterization of the hepatitis C virus NS2/3 processing reaction by using a purified precursor protein

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https://api.crossref.org/works/10.1016%2FS1471-4914%2802%2902395-X

7 January 2021

Molecular views of viral polyprotein processing revealed by the crystal structure of the hepatitis C virus bifunctional protease-helicase

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https://api.crossref.org/works/10.1016%2FS1471-4914%2802%2902395-X

7 January 2021

Expression of hepatitis C virus proteins induces distinct membrane alterations including a candidate viral replication complex

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2802%2902395-X

7 January 2021

Mutations in the nonstructural protein 5A gene and response to interferon in patients with chronic hepatitis C virus 1b infection

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2802%2902395-X

7 January 2021

Regulation of PKR and IRF-1 during hepatitis C virus RNA replication

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https://api.crossref.org/works/10.1016%2FS1471-4914%2802%2902395-X

7 January 2021

How hepatitis C virus counteracts the interferon response: the jury is still out on NS5A.

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https://api.crossref.org/works/10.1016%2FS1471-4914%2802%2902395-X

7 January 2021

Crystal structure of the RNA-dependent RNA polymerase from hepatitis C virus reveals a fully encircled active site

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https://api.crossref.org/works/10.1016%2FS1471-4914%2802%2902395-X

7 January 2021

Structural Analysis of the Hepatitis C Virus RNA Polymerase in Complex with Ribonucleotides

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https://api.crossref.org/works/10.1016%2FS1471-4914%2802%2902395-X

7 January 2021

Hepatitis C virus (HCV) NS5A binds RNA-dependent RNA polymerase (RdRP) NS5B and modulates RNA-dependent RNA polymerase activity

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2802%2902395-X

7 January 2021

Subcellular localization, stability, and trans-cleavage competence of the hepatitis C virus NS3-NS4A complex expressed in tetracycline-regulated cell lines

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https://api.crossref.org/works/10.1016%2FS1471-4914%2802%2902395-X

7 January 2021

Determinants for membrane association of the hepatitis C virus RNA-dependent RNA polymerase

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https://api.crossref.org/works/10.1016%2FS1471-4914%2802%2902395-X

7 January 2021

An amino-terminal amphipathic alpha-helix mediates membrane association of the hepatitis C virus nonstructural protein 5A

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2802%2902395-X

7 January 2021

Hepatitis C viral dynamics in vivo and the antiviral efficacy of interferon-alpha therapy

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https://api.crossref.org/works/10.1016%2FS1471-4914%2802%2902395-X

7 January 2021

Efficient initiation of HCV RNA replication in cell culture

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https://api.crossref.org/works/10.1016%2FS1471-4914%2802%2902395-X

7 January 2021

Mutations in Hepatitis C Virus RNAs Conferring Cell Culture Adaptation

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https://api.crossref.org/works/10.1016%2FS1471-4914%2802%2902395-X

7 January 2021

Interferon-alpha inhibits hepatitis C virus subgenomic RNA replication by an MxA-independent pathway

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2802%2902395-X

7 January 2021

Selectable subgenomic and genome-length dicistronic RNAs derived from an infectious molecular clone of the HCV-N strain of hepatitis C virus replicate efficiently in cultured Huh7 cells

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https://api.crossref.org/works/10.1016%2FS1471-4914%2802%2902395-X

7 January 2021

Transmission of hepatitis C virus infection to tree shrews

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2802%2902395-X

7 January 2021

Steatosis and liver cancer in transgenic mice expressing the structural and nonstructural proteins of hepatitis C virus

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2802%2902395-X

7 January 2021

Toward a surrogate model for hepatitis C virus: An infectious molecular clone of the GB virus-B hepatitis agent.

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2802%2902395-X

7 January 2021

Ribavirin Induces Error-Prone Replication of GB Virus B in Primary Tamarin Hepatocytes

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2802%2902395-X

7 January 2021

Hepatitis C virus replication in mice with chimeric human livers

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https://api.crossref.org/works/10.1016%2FS1471-4914%2802%2902395-X

7 January 2021

Vaccination of chimpanzees against infection by the hepatitis C virus

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https://api.crossref.org/works/10.1016%2FS1471-4914%2802%2902395-X

7 January 2021

Perspectives: towards a peptide-based vaccine against hepatitis C virus.

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https://api.crossref.org/works/10.1016%2FS1471-4914%2802%2902395-X

7 January 2021

Protection against persistence of hepatitis C.

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https://api.crossref.org/works/10.1016%2FS1471-4914%2802%2902395-X

7 January 2021

Lack of Protective Immunity Against Reinfection with Hepatitis C Virus

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https://api.crossref.org/works/10.1016%2FS1471-4914%2802%2902395-X

7 January 2021

Protective immune response to hepatitis C virus in chimpanzees rechallenged following clearance of primary infection

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https://api.crossref.org/works/10.1016%2FS1471-4914%2802%2902395-X

7 January 2021

Previously Infected and Recovered Chimpanzees Exhibit Rapid Responses That Control Hepatitis C Virus Replication upon Rechallenge

1 reference

https://api.crossref.org/works/10.1016%2FS1471-4914%2802%2902395-X

7 January 2021

10.1016/S1471-4914(02)02395-X

Identifiers

DOI

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5 August 2017

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