Overweight worsens apoptosis, neuroinflammation and blood-brain barrier damage after hypoxic ischemia in neonatal brain through JNK hyperactivation. (Q34957102)

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English	Overweight worsens apoptosis, neuroinflammation and blood-brain barrier damage after hypoxic ischemia in neonatal brain through JNK hyperactivation.	scientific article

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29 January 2020

Overweight worsens apoptosis, neuroinflammation and blood-brain barrier damage after hypoxic ischemia in neonatal brain through JNK hyperactivation (English)

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29 January 2020

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blood–brain barrier

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Chao-Ching Huang

5

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29 January 2020

author name string

Yi-Fang Tu

1

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29 January 2020

Yau-Sheng Tsai

2

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29 January 2020

Lan-Wan Wang

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29 January 2020

Hsin-Chieh Wu

4

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29 January 2020

Chien-Jung Ho

6

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29 January 2020

publication date

25 April 2011

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29 January 2020

Journal of Neuroinflammation

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29 January 2020

8

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29 January 2020

40

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29 January 2020

https://scigraph.springernature.com/pub.10.1186/1742-2094-8-40

0 references

Low-dose lipopolysaccharide selectively sensitizes hypoxic ischemia-induced white matter injury in the immature brain

1 reference

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Adipose tissue, inflammation and atherosclerosis

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8 July 2018

Lipopolysaccharide-induced apoptosis in transformed bovine brain endothelial cells and human dermal microvessel endothelial cells: the role of JNK

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VEGF-A/VEGFR-2 signaling leading to cAMP response element-binding protein phosphorylation is a shared pathway underlying the protective effect of preconditioning on neurons and endothelial cells.

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8 July 2018

JNK is activated but does not mediate hippocampal neuronal apoptosis in experimental neonatal pneumococcal meningitis

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8 July 2018

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8 July 2018

Hypoxia is a potential risk factor for chronic inflammation and adiponectin reduction in adipose tissue of ob/ob and dietary obese mice

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8 July 2018

Microglial activation and matrix protease generation during focal cerebral ischemia

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Potential new risk factors for ischemic stroke: what is their potential?

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Microglia and inflammation: impact on developmental brain injuries

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8 July 2018

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8 July 2018

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cAMP response element-binding protein activation in ligation preconditioning in neonatal brain

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8 July 2018

The c-Jun N-terminal protein kinase signaling pathway mediates Bax activation and subsequent neuronal apoptosis through interaction with Bim after transient focal cerebral ischemia

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8 July 2018

Abnormal fetal growth: intrauterine growth retardation, small for gestational age, large for gestational age.

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Obesity is associated with macrophage accumulation in adipose tissue

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A central role for JNK in obesity and insulin resistance

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Do white cells matter in white matter damage?

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Requirement of JNK for stress-induced activation of the cytochrome c-mediated death pathway

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8 July 2018

Vulnerability to cerebral hypoxic-ischemic insult in neonatal but not in adult rats is in parallel with disruption of the blood-brain barrier.

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8 July 2018

Moderate hyperglycemia worsens acute blood-brain barrier injury after forebrain ischemia in rats.

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8 July 2018

The influence of growth retardation on perinatal hypoxic-ischemic brain damage.

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8 July 2018

Effect of Litter Size on Weight Gain in Rats

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Measurement of the urinary lactate:creatinine ratio for the early identification of newborn infants at risk for hypoxic-ischemic encephalopathy.

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Influence of metabolic syndrome and general obesity on the risk of ischemic stroke.

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Distinct requirements for p38alpha and c-Jun N-terminal kinase stress-activated protein kinases in different forms of apoptotic neuronal death

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Different apoptotic mechanisms are activated in male and female brains after neonatal hypoxia-ischaemia

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Matrix metalloproteinase-9 gene knock-out protects the immature brain after cerebral hypoxia-ischemia.

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CREB activation in the rapid, intermediate, and delayed ischemic preconditioning against hypoxic-ischemia in neonatal rat.

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21 January 2018

Design and synthesis of the first generation of novel potent, selective, and in vivo active (benzothiazol-2-yl)acetonitrile inhibitors of the c-Jun N-terminal kinase.

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Maternal high-fat diet consumption results in fetal malprogramming predisposing to the onset of metabolic syndrome-like phenotype in adulthood.

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21 January 2018

Minocycline attenuates hypoxia-ischemia-induced neurological dysfunction and brain injury in the juvenile rat.

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21 January 2018

Microglia potentiate damage to blood-brain barrier constituents: improvement by minocycline in vivo and in vitro.

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Protein extravasation and cellular uptake after high-dose human-albumin treatment of transient focal cerebral ischemia in rats.

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Morphological and immunophenotypic microglial changes in the denervated fascia dentata of adult rats: correlation with blood-brain barrier damage and astroglial reactions.

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21 January 2018

Microglial and astroglial reactions to ischemic and kainic acid-induced lesions of the adult rat hippocampus.

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Amoeboid microglia in the periventricular white matter induce oligodendrocyte damage through expression of proinflammatory cytokines via MAP kinase signaling pathway in hypoxic neonatal rats.

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Role of c-Jun N-terminal kinase in early brain injury after subarachnoid hemorrhage.

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21 January 2018

Limited role of the c-Jun N-terminal kinase pathway in a neonatal rat model of cerebral hypoxia-ischemia.

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Deletion of the c-Jun N-terminal kinase 3 gene protects neonatal mice against cerebral hypoxic-ischaemic injury.

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26 October 2018

Nonparticipation of nuclear factor kappa B (NFkappaB) in the signaling cascade of c-Jun N-terminal kinase (JNK)- and p38 mitogen-activated protein kinase (p38MAPK)-dependent tumor necrosis factor alpha (TNFalpha) induction in lipopolysaccharide (LPS

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26 October 2018

The influence of litter size on brain damage caused by hypoxic-ischemic injury in the neonatal rat.

1 reference

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26 October 2018

The effect of hyperglycemia on cerebral metabolism during hypoxia-ischemia in the immature rat.

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26 October 2018

Glial swelling with eosinophilia in human post-mortem brains: a change indicative of plasma extravasation

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21 January 2018

Enhanced expression of Iba1, ionized calcium-binding adapter molecule 1, after transient focal cerebral ischemia in rat brain

1 reference

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Hypoxic-ischemic brain injury induces an acute microglial reaction in perinatal rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/21518436

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neonatal brain injury

1 reference

https://pubmed.ncbi.nlm.nih.gov/21518436

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

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10.1186/1742-2094-8-40

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29 January 2020

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29 January 2020

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29 January 2020

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