A role for interleukin-2 trans-presentation in dendritic cell-mediated T cell activation in humans, as revealed by daclizumab therapy (Q34949098)

5 August 2017

A role for interleukin-2 trans-presentation in dendritic cell-mediated T cell activation in humans, as revealed by daclizumab therapy (English)

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5 August 2017

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4

Sungpil Han

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5 August 2017

Simone C Wuest

1

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5 August 2017

Jehad H Edwan

2

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5 August 2017

Jayne F Martin

3

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5 August 2017

Justin S A Perry

5

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5 August 2017

Casandra M Cartagena

6

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5 August 2017

Eiji Matsuura

7

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5 August 2017

Dragan Maric

8

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5 August 2017

Thomas A Waldmann

9

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5 August 2017

Bibiana Bielekova

10

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5 August 2017

language of work or name

English

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publication date

1 May 2011

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5 August 2017

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5 August 2017

17

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5 August 2017

604-609

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5 August 2017

5

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https://scigraph.springernature.com/pub.10.1038/nm.2365

5 August 2017

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cites work

An IL-2 paradox: blocking CD25 on T cells induces IL-2-driven activation of CD56(bright) NK cells

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24S-hydroxycholesterol effects on lipid metabolism genes are modeled in traumatic brain injury

8 July 2018

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Effect of anti-CD25 antibody daclizumab in the inhibition of inflammation and stabilization of disease progression in multiple sclerosis.

8 July 2018

1 reference

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Regulatory T cells are reduced during anti-CD25 antibody treatment of multiple sclerosis.

8 July 2018

1 reference

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IL-2- and CD25-dependent immunoregulatory mechanisms in the homeostasis of T-cell subsets

8 July 2018

1 reference

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Tonsilar NK cells restrict B cell transformation by the Epstein-Barr virus via IFN-gamma

8 July 2018

1 reference

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The biology of interleukin-2.

8 July 2018

1 reference

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Daclizumab phase II trial in relapsing and remitting multiple sclerosis: MRI and clinical results

8 July 2018

1 reference

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Syk-dependent ERK activation regulates IL-2 and IL-10 production by DC stimulated with zymosan

8 July 2018

1 reference

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CD25 deficiency causes an immune dysregulation, polyendocrinopathy, enteropathy, X-linked-like syndrome, and defective IL-10 expression from CD4 lymphocytes

8 July 2018

1 reference

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Intravenous immunoglobulin ameliorates ITP via activating Fc gamma receptors on dendritic cells

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3089658

Regulatory CD56(bright) natural killer cells mediate immunomodulatory effects of IL-2Ralpha-targeted therapy (daclizumab) in multiple sclerosis.

8 July 2018

1 reference

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Structure of the quaternary complex of interleukin-2 with its alpha, beta, and gammac receptors

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3089658

Homeostatic maintenance of natural Foxp3(+) CD25(+) CD4(+) regulatory T cells by interleukin (IL)-2 and induction of autoimmune disease by IL-2 neutralization

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3089658

Humanized anti-CD25 (daclizumab) inhibits disease activity in multiple sclerosis patients failing to respond to interferon beta

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3089658

Dendritic cell regulation of immune responses: a new role for interleukin 2 at the intersection of innate and adaptive immunity

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3089658

IL-15Ralpha recycles and presents IL-15 In trans to neighboring cells

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3089658

Inducible IL-2 production by dendritic cells revealed by global gene expression analysis.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3089658

Signaling via the IL-2 and IL-7 receptors from the membrane to the nucleus

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3089658

Treatment of noninfectious intermediate and posterior uveitis with the humanized anti-Tac mAb: a phase I/II clinical trial

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3089658

Human immune disorder arising from mutation of the alpha chain of the interleukin-2 receptor

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3089658

Interleukin-2 receptor alpha chain regulates the size and content of the peripheral lymphoid compartment

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3089658

Selective in Vitro Growth of T Lymphocytes from Normal Human Bone Marrows

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3089658

Daclizumab in active relapsing multiple sclerosis (CHOICE study): a phase 2, randomised, double-blind, placebo-controlled, add-on trial with interferon beta

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3089658

Anti-CD25 antibodies decrease the ability of human dendritic cells to prime allogeneic CD4 T cells.

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3089658

Anti-CD25 antibodies affect cytokine synthesis pattern of human dendritic cells and decrease their ability to prime allogeneic CD4+ T cells.

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3089658

IL-2 receptor alpha deficiency and features of primary biliary cirrhosis

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3089658

Does the IL-2 receptor alpha chain induced on dendritic cells have a biological function?

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3089658

Interleukin-2 programs mouse alpha beta T lymphocytes for apoptosis

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3089658

Encephalitogenic potential of the myelin basic protein peptide (amino acids 83-99) in multiple sclerosis: results of a phase II clinical trial with an altered peptide ligand

26 October 2018

1 reference

12 December 2020

Human IL-2 receptor alpha chain deficiency

1 reference

12 December 2020

The use of antibodies against the IL-2 receptor in transplantation

1 reference

12 December 2020

Enhanced T-cell activation and T-cell-dependent IL-2 production by CD83+, CD25high, CD43high human monocyte-derived dendritic cells

1 reference

12 December 2020

Anti CD25 treatment of human dendritic cells modulates both their cytokine synthesis profiles and their capacity to activate allogeneic CD4 T cells: a potential tolerogenic effect

1 reference

12 December 2020

Identifiers

DOI

10.1038/NM.2365

1 reference

Dimensions Publication ID

5 August 2017

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1 reference

5 August 2017

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