Focal adhesion kinase (FAK) binds RET kinase via its FERM domain, priming a direct and reciprocal RET-FAK transactivation mechanism. (Q34948215)

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27 January 2020

title

Focal adhesion kinase (FAK) binds RET kinase via its FERM domain, priming a direct and reciprocal RET-FAK transactivation mechanism (English)

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27 January 2020

2

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Carlo Gambacorti-Passerini

27 January 2020

5

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27 January 2020

Robert Hofstra

7

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27 January 2020

Clare M Isacke

10

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27 January 2020

author name string

Iván Plaza-Menacho

1

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27 January 2020

Luca Mologni

3

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27 January 2020

Piet Boender

4

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27 January 2020

Anthony I Magee

6

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27 January 2020

Phillip Knowles

8

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27 January 2020

Neil Q McDonald

9

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27 January 2020

language of work or name

English

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publication date

22 March 2011

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Journal of Biological Chemistry

27 January 2020

published in

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volume

286

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issue

19

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page(s)

17292-17302

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Targeting the receptor tyrosine kinase RET sensitizes breast cancer cells to tamoxifen treatment and reveals a role for RET in endocrine resistance.

27 January 2020

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8 July 2018

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A rapid method for the purification of wild-type and V804M mutant ret catalytic domain: A tool to study thyroid cancer

8 July 2018

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Crystal structure of the FERM domain of focal adhesion kinase.

8 July 2018

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Direct phosphorylation of proliferative and survival pathway proteins by RET.

8 July 2018

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Expression, purification, and inhibition of human RET tyrosine kinase

8 July 2018

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Peptide arrays for kinase profiling

8 July 2018

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8 July 2018

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8 July 2018

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8 July 2018

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8 July 2018

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Crossref

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Expression profiling of serous low malignant potential, low-grade, and high-grade tumors of the ovary.

21 January 2018

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Immunohistochemical analyses of focal adhesion kinase expression in benign and malignant human breast and colon tissues: correlation with preinvasive and invasive phenotypes

21 January 2018

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12 December 2020

Focal adhesion kinase is not essential for in vitro and in vivo differentiation of ES cells

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12 December 2020

Focal adhesion kinase (pp125FAK) expression, activation and association with paxillin and p50CSK in human metastatic prostate carcinoma

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12 December 2020

Overexpression of focal adhesion kinase (p125FAK) in human colorectal carcinoma liver metastases: independence from c-src or c-yes activation

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12 December 2020

Identifiers

DOI

10.1074/JBC.M110.168500

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21454698%20AND%20SRC:MED&resulttype=core&format=json

27 January 2020

1 reference

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27 January 2020

PubMed publication ID

21454698

1 reference