Tolerance of whole-genome doubling propagates chromosomal instability and accelerates cancer genome evolution. (Q34946877)

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5 March 2020

title

Tolerance of whole-genome doubling propagates chromosomal instability and accelerates cancer genome evolution (English)

1 reference

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5 March 2020

main subject

whole genome sequencing

1 reference

10

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5 March 2020

Zoltan Szallasi

12

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5 March 2020

Nicholas McGranahan

2

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5 March 2020

Eva Gronroos

5

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5 March 2020

Peter Gibbs

9

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5 March 2020

Nicholas J. Hawkins

11

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5 March 2020

Oliver Sieber

13

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5 March 2020

Charles Swanton

14

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5 March 2020

1

Sally M Dewhurst

1 reference

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5 March 2020

6

David Endesfelder

1 reference

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5 March 2020

3

Rebecca A Burrell

1 reference

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5 March 2020

7

Tejal Joshi

1 reference

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5 March 2020

author name string

Andrew J Rowan

4

1 reference

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5 March 2020

Dmitri Mouradov

8

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5 March 2020

publication date

19 January 2014

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5 March 2020

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5 March 2020

volume

4

1 reference

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5 March 2020

page(s)

175-185

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5 March 2020

issue

2

1 reference

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Pan-cancer patterns of somatic copy number alteration

5 March 2020

cites work

1 reference

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Punctuated evolution of prostate cancer genomes

8 July 2018

1 reference

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Replication stress links structural and numerical cancer chromosomal instability

8 July 2018

1 reference

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Genetic instability: tipping the balance

8 July 2018

1 reference

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Polyploidy and the evolution of complex traits

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4293454

Telomere-driven tetraploidization occurs in human cells undergoing crisis and promotes transformation of mouse cells

8 July 2018

1 reference

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The life history of 21 breast cancers

8 July 2018

1 reference

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Cancer chromosomal instability: therapeutic and diagnostic challenges

8 July 2018

1 reference

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Absolute quantification of somatic DNA alterations in human cancer

8 July 2018

1 reference

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Intratumor Heterogeneity and Branched Evolution Revealed by Multiregion Sequencing

8 July 2018

1 reference

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The causes and consequences of polyploidy in normal development and cancer

8 July 2018

1 reference

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Chromosomal instability confers intrinsic multidrug resistance.

8 July 2018

1 reference

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Massive genomic rearrangement acquired in a single catastrophic event during cancer development

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4293454

A statistical approach for detecting genomic aberrations in heterogeneous tumor samples from single nucleotide polymorphism genotyping data

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4293454

Proliferation of aneuploid human cells is limited by a p53-dependent mechanism.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4293454

Reoperation for recurrent colorectal cancer

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4293454

PICNIC: an algorithm to predict absolute allelic copy number variation with microarray cancer data

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4293454

Chromosomal instability: a composite phenotype that influences sensitivity to chemotherapy

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4293454

A mechanism linking extra centrosomes to chromosomal instability

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4293454

Deregulated Aurora-B induced tetraploidy promotes tumorigenesis

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4293454

A single-sample method for normalizing and combining full-resolution copy numbers from multiple platforms, labs and analysis methods

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4293454

The consequences of tetraploidy and aneuploidy

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4293454

Examining the link between chromosomal instability and aneuploidy in human cells

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4293454

DNA ploidy status and prognosis in colorectal cancer: a meta-analysis of published data

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4293454

Genetic clonal diversity predicts progression to esophageal adenocarcinoma

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4293454

Cytokinesis failure generating tetraploids promotes tumorigenesis in p53-null cells

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4293454

The role of the DNA mismatch repair system in the cytotoxicity of the topoisomerase inhibitors camptothecin and etoposide to human colorectal cancer cells.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4293454

Establishment of an oriP replicon is dependent upon an infrequent, epigenetic event

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4293454

17p (p53) allelic losses, 4N (G2/tetraploid) populations, and progression to aneuploidy in Barrett's esophagus

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4293454

Deletion of chromosome 4q predicts outcome in stage II colon cancer patients

8 July 2018

1 reference

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A virus causes cancer by inducing massive chromosomal instability through cell fusion

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4293454

Tetraploidy and chromosomal instability are early events during cervical carcinogenesis

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4293454

Model for the genetic evolution of human solid tumors

26 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24436049

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Genome-wide genetic analysis of polyploidy in yeast

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24436049

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1158/2159-8290.CD-13-0285

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24436049%20AND%20SRC:MED&resulttype=core&format=json

5 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24436049%20AND%20SRC:MED&resulttype=core&format=json

5 March 2020

1 reference