SGK3 is an estrogen-inducible kinase promoting estrogen-mediated survival of breast cancer cells. (Q34942979)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21084382%20AND%20SRC:MED&resulttype=core&format=json

16 January 2020

title

SGK3 is an estrogen-inducible kinase promoting estrogen-mediated survival of breast cancer cells (English)

1 reference

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16 January 2020

1 reference

1

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16 January 2020

David D. Smith

5

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16 January 2020

author name string

Dujin Zhou

2

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16 January 2020

Sheryl Phung

3

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16 January 2020

Selma Masri

4

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16 January 2020

Shiuan Chen

6

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16 January 2020

language of work or name

1 reference

17 November 2010

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16 January 2020

published in

Molecular Endocrinology

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16 January 2020

volume

25

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16 January 2020

issue

1

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16 January 2020

page(s)

72-82

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Relationship between estrogen receptor alpha location and gene induction reveals the importance of downstream sites and cofactors

16 January 2020

cites work

1 reference

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AKT-independent signaling downstream of oncogenic PIK3CA mutations in human cancer

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Phosphatidylinositol-3-kinase and AKT1 mutations occur early in breast carcinoma

8 July 2018

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ChIP-Seq of ERalpha and RNA polymerase II defines genes differentially responding to ligands

8 July 2018

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Identification of Flightless-I as a substrate of the cytokine-independent survival kinase CISK.

8 July 2018

1 reference

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Development of a small-molecule serum- and glucocorticoid-regulated kinase-1 antagonist and its evaluation as a prostate cancer therapeutic.

8 July 2018

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PTEN-deficient cancers depend on PIK3CB.

8 July 2018

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Identification and characterization of PNRC splicing variants.

8 July 2018

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Genome-wide analysis of aromatase inhibitor-resistant, tamoxifen-resistant, and long-term estrogen-deprived cells reveals a role for estrogen receptor

8 July 2018

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Meta-analysis of breast cancer microarray studies in conjunction with conserved cis-elements suggest patterns for coordinate regulation

8 July 2018

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DNA oxidation as triggered by H3K9me2 demethylation drives estrogen-induced gene expression

8 July 2018

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Mechanisms of primary and secondary estrogen target gene regulation in breast cancer cells

8 July 2018

1 reference

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Serum/glucocorticoid-induced protein kinase-1 facilitates androgen receptor-dependent cell survival

8 July 2018

1 reference

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(Patho)physiological significance of the serum- and glucocorticoid-inducible kinase isoforms

8 July 2018

1 reference

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Genome-wide analysis of estrogen receptor binding sites

8 July 2018

1 reference

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CISK attenuates degradation of the chemokine receptor CXCR4 via the ubiquitin ligase AIP4

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3089033

Serum and glucocorticoid-regulated protein kinases: variations on a theme

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3089033

Up-regulation of PI3K/Akt signaling by 17beta-estradiol through activation of estrogen receptor-alpha, but not estrogen receptor-beta, and stimulates cell growth in breast cancer cells

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3089033

Survival signals generated by estrogen and phospholipase D in MCF-7 breast cancer cells are dependent on Myc.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3089033

Chromosome-wide mapping of estrogen receptor binding reveals long-range regulation requiring the forkhead protein FoxA1

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3089033

Multiple mechanisms induce transcriptional silencing of a subset of genes, including oestrogen receptor alpha, in response to deacetylase inhibition by valproic acid and trichostatin A.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3089033

Letrozole-, anastrozole-, and tamoxifen-responsive genes in MCF-7aro cells: a microarray approach

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3089033

PIK3CA mutations correlate with hormone receptors, node metastasis, and ERBB2, and are mutually exclusive with PTEN loss in human breast carcinoma

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3089033

Estradiol rapidly activates Akt via the ErbB2 signaling pathway.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3089033

The phosphatidylinositol 3-Kinase AKT pathway in human cancer

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3089033

The phosphoinositide 3-kinase pathway

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3089033

Regulation and physiological roles of serum- and glucocorticoid-induced protein kinase isoforms

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3089033

Activation of the Akt-related cytokine-independent survival kinase requires interaction of its phox domain with endosomal phosphatidylinositol 3-phosphate

8 July 2018

1 reference

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Regulation of cytokine-independent survival kinase (CISK) by the Phox homology domain and phosphoinositides

8 July 2018

1 reference

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Estrogens and cell-cycle regulation in breast cancer

8 July 2018

1 reference

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Studies of apoptosis in breast cancer

8 July 2018

1 reference

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Phosphatidylinositol 3-kinase/AKT-mediated activation of estrogen receptor alpha: a new model for anti-estrogen resistance

8 July 2018

1 reference

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Identification of CISK, a new member of the SGK kinase family that promotes IL-3-dependent survival

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3089033

17beta-estradiol inhibits apoptosis in MCF-7 cells, inducing bcl-2 expression via two estrogen-responsive elements present in the coding sequence.

8 July 2018

1 reference

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The pure antiestrogen ICI 182780 is more effective in the induction of apoptosis and down regulation of BCL-2 than tamoxifen in MCF-7 cells

8 July 2018

1 reference

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Cloning and mapping of a novel human serum/glucocorticoid regulated kinase-like gene, SGKL, to chromosome 8q12.3-q13.1

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3089033

Characterization of the structure and regulation of two novel isoforms of serum- and glucocorticoid-induced protein kinase

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3089033

Characterization of sgk, a novel member of the serine/threonine protein kinase gene family which is transcriptionally induced by glucocorticoids and serum

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3089033

Impact of estrogen deprivation on gene expression profiles of normal postmenopausal breast tissue in vivo

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3089033

Regulation of the epithelial calcium channel TRPV6 by the serum and glucocorticoid-inducible kinase isoforms SGK1 and SGK3.

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3089033

Transcriptional regulation of the mouse PNRC2 promoter by the nuclear factor Y (NFY) and E2F1.

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3089033

Meta-analysis of microarrays: interstudy validation of gene expression profiles reveals pathway dysregulation in prostate cancer.

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3089033

Induction of apoptosis in mammary gland by a pure anti-estrogen ICI 182780.

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3089033

Tissue-specific expression of the transcriptionally regulated serum and glucocorticoid-inducible protein kinase (Sgk) during mouse embryogenesis

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3089033

26 October 2018

Identifiers

DOI

10.1210/ME.2010-0294

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21084382%20AND%20SRC:MED&resulttype=core&format=json

16 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21084382%20AND%20SRC:MED&resulttype=core&format=json

16 January 2020

1 reference