Analysis of virulence and inflammatory potential of Shigella flexneri purine biosynthesis mutants (Q34941041)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14638790%20AND%20SRC:MED&resulttype=core&format=json

21 December 2019

title

Analysis of virulence and inflammatory potential of Shigella flexneri purine biosynthesis mutants (English)

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21 December 2019

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Maria Lina Bernardini

5

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21 December 2019

author name string

Antonella Cersini

1

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21 December 2019

Maria Celeste Martino

2

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21 December 2019

Irene Martini

3

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21 December 2019

Giacomo Rossi

4

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21 December 2019

language of work or name

English

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publication date

1 December 2003

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21 December 2019

published in

Infection and Immunity

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21 December 2019

volume

71

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21 December 2019

issue

12

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21 December 2019

page(s)

7002-7013

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A Chromosomal Locus Which Controls the Ability of Shigella flexneri to Evoke Keratoconjunctivitis.

21 December 2019

cites work

1 reference

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Attenuated Shigella flexneri 2a Delta guaBA strain CVD 1204 expressing enterotoxigenic Escherichia coli (ETEC) CS2 and CS3 fimbriae as a live mucosal vaccine against Shigella and ETEC infection

8 July 2018

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Parameters underlying successful protection with live attenuated mutants in experimental shigellosis

8 July 2018

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Attenuated Shigella flexneri 2a vaccine strain CVD 1204 expressing colonization factor antigen I and mutant heat-labile enterotoxin of enterotoxigenic Escherichia coli

8 July 2018

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Reactive oxygen and nitrogen intermediates in the relationship between mammalian hosts and microbial pathogens

8 July 2018

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Shigella flexneri 2a strain CVD 1207, with specific deletions in virG, sen, set, and guaBA, is highly attenuated in humans

8 July 2018

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Global burden of Shigella infections: implications for vaccine development and implementation of control strategies

8 July 2018

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Vaccination against shigellosis with attenuated Shigella flexneri 2a strain SC602

8 July 2018

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Interleukin-8 controls bacterial transepithelial translocation at the cost of epithelial destruction in experimental shigellosis.

8 July 2018

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Type III protein secretion systems in bacterial pathogens of animals and plants

8 July 2018

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Intracellular multiplication and virulence of Shigella flexneri auxotrophic mutants.

8 July 2018

1 reference

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Uptake of pathogenic intracellular bacteria into human and murine macrophages downregulates the eukaryotic 26S protease complex ATPase gene

8 July 2018

1 reference

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Shigella flexneri is trapped in polymorphonuclear leukocyte vacuoles and efficiently killed

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=308888

In vivo apoptosis in Shigella flexneri infections

8 July 2018

1 reference

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Engineered deltaguaB-A deltavirG Shigella flexneri 2a strain CVD 1205: construction, safety, immunogenicity, and potential efficacy as a mucosal vaccine

8 July 2018

1 reference

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Construction and evaluation of a virG thyA double mutant of Shigella flexneri 2a as a candidate live-attenuated oral vaccine

8 July 2018

1 reference

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Further characterization of delta aroA delta virG Shigella flexneri 2a strain CVD 1203 as a mucosal Shigella vaccine and as a live-vector vaccine for delivering antigens of enterotoxigenic Escherichia coli

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=308888

Concentrations of interleukin 6 and tumour necrosis factor in serum and stools of children with Shigella dysenteriae 1 infection.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=308888

Nonpolar mutagenesis of the ipa genes defines IpaB, IpaC, and IpaD as effectors of Shigella flexneri entry into epithelial cells

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=308888

Antibody and cytokine responses in a mouse pulmonary model of Shigella flexneri serotype 2a infection.

8 July 2018

1 reference

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Role of interleukin-1 in the pathogenesis of experimental shigellosis

8 July 2018

1 reference

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Monoclonal immunoglobulin A antibody directed against serotype-specific epitope of Shigella flexneri lipopolysaccharide protects against murine experimental shigellosis

8 July 2018

1 reference

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Multiplication of Shigella flexneri within HeLa cells: lysis of the phagocytic vacuole and plasmid-mediated contact hemolysis

8 July 2018

1 reference

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Development of an auxotrophic oral live Shigella flexneri vaccine

8 July 2018

1 reference

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Identification of icsA, a plasmid locus of Shigella flexneri that governs bacterial intra- and intercellular spread through interaction with F-actin

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=308888

Construction of aromatic dependent Shigella flexneri 2a live vaccine candidate strains: deletion mutations in the aroA and the aroD genes

8 July 2018

1 reference

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Small-animal model to measure efficacy and immunogenicity of Shigella vaccine strains

8 July 2018

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OmpB (osmo-regulation) and icsA (cell-to-cell spread) mutants of Shigella flexneri: vaccine candidates and probes to study the pathogenesis of shigellosis

8 July 2018

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Shigella flexneri induces apoptosis in infected macrophages

8 July 2018

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icsB: a Shigella flexneri virulence gene necessary for the lysis of protrusions during intercellular spread

8 July 2018

1 reference

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Two msbB genes encoding maximal acylation of lipid A are required for invasive Shigella flexneri to mediate inflammatory rupture and destruction of the intestinal epithelium

8 July 2018

1 reference

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Protection of adult rabbits and monkeys from lethal shigellosis by oral immunization with a thymine-requiring and temperature-sensitive mutant of Shigella flexneri Y

26 October 2018

1 reference

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DeltaguaBA attenuated Shigella flexneri 2a strain CVD 1204 as a Shigella vaccine and as a live mucosal delivery system for fragment C of tetanus toxin

26 October 2018

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12 December 2020

Caspase-1 activation of IL-1beta and IL-18 are essential for Shigella flexneri-induced inflammation

1 reference

12 December 2020

Single-step elimination of contaminating DNA prior to reverse transcriptase PCR

1 reference

12 December 2020

Immune responses elicited against multiple enterotoxigenic Escherichia coli fimbriae and mutant LT expressed in attenuated Shigella vaccine strains

1 reference

12 December 2020

High-Density Presentation of an Immunodominant Minimal Peptide on B Cells Is MHC-Linked to Th1-like Immunity

1 reference

12 December 2020

Invasive Shigella flexneri activates NF-kappa B through a lipopolysaccharide-dependent innate intracellular response and leads to IL-8 expression in epithelial cells

1 reference

12 December 2020

Evaluation of Shigella vaccine safety and efficacy in an intranasally challenged mouse model

1 reference

12 December 2020

10.1128/IAI.71.12.7002-7013.2003

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14638790%20AND%20SRC:MED&resulttype=core&format=json

21 December 2019

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:14638790%20AND%20SRC:MED&resulttype=core&format=json

21 December 2019

PubMed publication ID

14638790

1 reference