Lupus risk variants in the PXK locus alter B-cell receptor internalization (Q34881641)

5 August 2017

Lupus risk variants in the PXK locus alter B-cell receptor internalization (English)

1 reference

5 August 2017

Xiaoming Lu

3

0 references

Joel M Guthridge

Joel M Guthridge

39

0 references

Leah C. Kottyan

Leah C Kottyan

47

0 references

Robert P. Kimberly

Robert P Kimberly

32

0 references

Marta E Alarcón-Riquelme

Marta E Alarcón-Riquelme

29

0 references

Sang-Cheol Bae

Sang-Cheol Bae

36

0 references

Juan-Manuel Anaya

Juan-Manuel Anaya

24

0 references

Timothy Vyse

38

Timothy J Vyse

1 reference

5 August 2017

23

John D Reveille

1 reference

5 August 2017

30

Michelle Petri

1 reference

5 August 2017

46

John B Harley

1 reference

5 August 2017

25

Judith A James

1 reference

5 August 2017

42

Carl D Langefeld

1 reference

5 August 2017

16

Barry I Freedman

1 reference

5 August 2017

21

Gary S Gilkeson

1 reference

5 August 2017

27

Lindsey A Criswell

1 reference

5 August 2017

41

Patrick M Gaffney

1 reference

5 August 2017

9

Mary E Comeau

1 reference

5 August 2017

17

Betty P Tsao

1 reference

5 August 2017

8

Julie T Ziegler

1 reference

5 August 2017

22

Graciela S Alarcón

1 reference

5 August 2017

19

Diane L Kamen

1 reference

5 August 2017

Rosalind Ramsey-Goldman

33

Rosalind Ramsey-Goldman

1 reference

5 August 2017

10

Miranda C Marion

1 reference

5 August 2017

37

Susan A Boackle

1 reference

5 August 2017

44

Jennifer A Kelly

1 reference

5 August 2017

31

R Hal Scofield

1 reference

5 August 2017

26

Kathy L Moser

1 reference

5 August 2017

40

Bahram Namjou

1 reference

5 August 2017

45

Isaac T W Harley

1 reference

5 August 2017

5

Erin E Zoller

1 reference

5 August 2017

14

Swapan Nath

1 reference

5 August 2017

4

Zubin H Patel

1 reference

5 August 2017

6

Albert F Magnusen

1 reference

5 August 2017

35

Jeongim Choi

1 reference

5 August 2017

Corinne Foley

2

0 references

author name string

Samuel E Vaughn

1

1 reference

5 August 2017

Adrienne H Williams

7

1 reference

5 August 2017

Stuart B Glenn

11

1 reference

5 August 2017

Adam Adler

12

1 reference

5 August 2017

Nan Shen

13

1 reference

5 August 2017

Anne M Stevens

15

1 reference

5 August 2017

Chaim O Jacob

18

1 reference

5 August 2017

Elizabeth E Brown

20

1 reference

5 August 2017

Luis M Vilá

28

1 reference

5 August 2017

Young Binjoo

34

1 reference

5 August 2017

Kenneth M Kaufman

43

1 reference

5 August 2017

1 January 2014

1 reference

5 August 2017

Frontiers in Genetics

1 reference

5 August 2017

5

1 reference

5 August 2017

450

1 reference

The IRF5-TNPO3 association with systemic lupus erythematosus has two components that other autoimmune disorders variably share

5 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4288052

Do follicular dendritic cells regulate lupus-specific B cells?

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4288052

Immunochip analysis identifies multiple susceptibility loci for systemic sclerosis

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4288052

Implication of the anti-inflammatory bioactive lipid prostaglandin D2-glycerol ester in the control of macrophage activation and inflammation by ABHD6.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4288052

The serine hydrolase ABHD6 Is a critical regulator of the metabolic syndrome

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4288052

Systematic identification of trans eQTLs as putative drivers of known disease associations

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4288052

Endocannabinoid metabolism in the prefrontal cortex in schizophrenia

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4288052

On combining reference data to improve imputation accuracy

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4288052

B-cell selection and the development of autoantibodies

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4288052

Selective inhibition of alpha/beta-hydrolase domain 6 attenuates neurodegeneration, alleviates blood brain barrier breakdown, and improves functional recovery in a mouse model of traumatic brain injury

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4288052

Bayesian refinement of association signals for 14 loci in 3 common diseases

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4288052

Genetic susceptibility to lupus: the biological basis of genetic risk found in B cell signaling pathways.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4288052

Identification of IRF8, TMEM39A, and IKZF3-ZPBP2 as susceptibility loci for systemic lupus erythematosus in a large-scale multiracial replication study

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4288052

Genotype imputation with thousands of genomes

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4288052

Performance of genotype imputations using data from the 1000 Genomes Project

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4288052

A comprehensive analysis of shared loci between systemic lupus erythematosus (SLE) and sixteen autoimmune diseases reveals limited genetic overlap

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4288052

Endocytosed BCRs sequentially regulate MAPK and Akt signaling pathways from intracellular compartments

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4288052

Integrating autoimmune risk loci with gene-expression data identifies specific pathogenic immune cell subsets

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4288052

Identification of a systemic lupus erythematosus susceptibility locus at 11p13 between PDHX and CD44 in a multiethnic study

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4288052

The lupus family registry and repository

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4288052

Integrating common and rare genetic variation in diverse human populations

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4288052

Haploview: Visualization and analysis of SNP genotype data

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4288052

Characterization of PXK as a protein involved in epidermal growth factor receptor trafficking

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4288052

Vav and Rac activation in B cell antigen receptor endocytosis involves Vav recruitment to the adapter protein LAB.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4288052

A large-scale replication study identifies TNIP1, PRDM1, JAZF1, UHRF1BP1 and IL10 as risk loci for systemic lupus erythematosus

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4288052

Bayesian statistical methods for genetic association studies

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4288052

B cell antigen receptor endocytosis and antigen presentation to T cells require Vav and dynamin.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4288052

Replication of recently identified systemic lupus erythematosus genetic associations: a case-control study

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4288052

Genetic variants near TNFAIP3 on 6q23 are associated with systemic lupus erythematosus

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4288052

The B cell receptor governs the subcellular location of Toll-like receptor 9 leading to hyperresponses to DNA-containing antigens

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4288052

A panel of ancestry informative markers for estimating individual biogeographical ancestry and admixture from four continents: utility and applications

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4288052

Estimating local ancestry in admixed populations

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4288052

Genome-wide association scan in women with systemic lupus erythematosus identifies susceptibility variants in ITGAM, PXK, KIAA1542 and other loci

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4288052

A comprehensive profile of brain enzymes that hydrolyze the endocannabinoid 2-arachidonoylglycerol

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4288052

PLINK: a tool set for whole-genome association and population-based linkage analyses

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4288052

A new multipoint method for genome-wide association studies by imputation of genotypes

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4288052

Principal components analysis corrects for stratification in genome-wide association studies

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4288052

The Phox (PX) domain proteins and membrane traffic

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4288052

Expression pattern and subcellular localization of five splice isoforms of human PXK

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4288052

MONaKA, a novel modulator of the plasma membrane Na,K-ATPase

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4288052

B cell selection and susceptibility to autoimmunity

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4288052

Haploview: analysis and visualization of LD and haplotype maps

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4288052

A High-Density Admixture Map for Disease Gene Discovery in African Americans

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4288052

Design and analysis of admixture mapping studies

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4288052

Control of confounding of genetic associations in stratified populations

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4288052

Genetic Power Calculator: design of linkage and association genetic mapping studies of complex traits

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4288052

Analysis of Relative Gene Expression Data Using Real-Time Quantitative PCR and the 2−ΔΔCT Method

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4288052

The Phox homology (PX) domain, a new player in phosphoinositide signalling

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4288052

Estimation of admixture and detection of linkage in admixed populations by a Bayesian approach: application to African-American populations

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4288052

B cells are required for lupus nephritis in the polygenic, Fas-intact MRL model of systemic autoimmunity.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4288052

Updating the American College of Rheumatology revised criteria for the classification of systemic lupus erythematosus

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4288052

The role of B cells in lpr/lpr-induced autoimmunity

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4288052

Loss-of-function variant in DNASE1L3 causes a familial form of systemic lupus erythematosus

8 July 2018

1 reference

https://api.crossref.org/works/10.3389%2FFGENE.2014.00450

PXK locus in systemic lupus erythematosus: fine mapping and functional analysis reveals novel susceptibility gene ABHD6.

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFGENE.2014.00450

The Phox homology (PX) domain, a new player in phosphoinositide signalling

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFGENE.2014.00450

A new role for B cells in systemic autoimmunity: B cells promote spontaneous T cell activation in MRL-lpr/lpr mice.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4288052

Promoter Insertion/Deletion in the IRF5 Gene Is Highly Associated with Susceptibility to Systemic Lupus Erythematosus in Distinct Populations, But Exerts a Modest Effect on Gene Expression in Peripheral Blood Mononuclear Cells

26 October 2018

1 reference

https://api.crossref.org/works/10.3389%2FFGENE.2014.00450

The PtdIns3P-Binding Protein Phafin 2 Mediates Epidermal Growth Factor Receptor Degradation by Promoting Endosome Fusion

21 January 2018

1 reference

https://api.crossref.org/works/10.3389%2FFGENE.2014.00450

21 January 2018

Identifiers

DOI

10.3389/FGENE.2014.00450

1 reference

5 August 2017

1 reference

5 August 2017

1 reference