Centrosome amplification and the development of cancer (Q34818152)

4 August 2017

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title

Centrosome amplification and the development of cancer (English)

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4 August 2017

2

Wilma L Lingle

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4 August 2017

3

Jeffrey L Salisbury

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4 August 2017

Antonino B D'Assoro

1

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PubMed ID

12214243

4 August 2017

language of work or name

English

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publication date

1 September 2002

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4 August 2017

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4 August 2017

21

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4 August 2017

6146-6153

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4 August 2017

40

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https://scigraph.springernature.com/pub.10.1038/sj.onc.1205772

4 August 2017

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cites work

Spindle pole body duplication: a model for centrosome duplication?

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205772

pavarotti encodes a kinesin-like protein required to organize the central spindle and contractile ring for cytokinesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205772

Differential subcellular localization of protein phosphatase-1 alpha, gamma1, and delta isoforms during both interphase and mitosis in mammalian cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205772

GFP tagging reveals human Polo-like kinase 1 at the kinetochore/centromere region of mitotic chromosomes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205772

Dissociation of centrosome replication events from cycles of DNA synthesis and mitotic division in hydroxyurea-arrested Chinese hamster ovary cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205772

Centriole disassembly in vivo and its effect on centrosome structure and function in vertebrate cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205772

Cell cycle-dependent localization of casein kinase I to mitotic spindles.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205772

Both viral (adenovirus E1B) and cellular (hsp 70, p53) components interact with centrosomes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205772

Centrosome hyperamplification in human cancer: chromosome instability induced by p53 mutation and/or Mdm2 overexpression.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205772

p53 displacement from centrosomes and p53-mediated G1 arrest following transient inhibition of the mitotic spindle.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205772

Cyclin B is associated with centrosomes in Drosophila mitotic cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205772

Pericentrin anchors protein kinase A at the centrosome through a newly identified RII-binding domain

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205772

Mice deficient for p53 are developmentally normal but susceptible to spontaneous tumours

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205772

Re-evaluating centrosome function

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205772

Centrosome abnormalities and genomic instability by episomal expression of human papillomavirus type 16 in raft cultures of human keratinocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205772

The human papillomavirus type 16 E6 and E7 oncoproteins cooperate to induce mitotic defects and genomic instability by uncoupling centrosome duplication from the cell division cycle

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205772

Genetic instability of cancer cells is proportional to their degree of aneuploidy

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205772

Motile organelles: the importance of specific tubulin isoforms

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205772

The tubulin fraternity: alpha to eta

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205772

WAF1, a potential mediator of p53 tumor suppression

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205772

The mouse Mps1p-like kinase regulates centrosome duplication

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205772

Activity of the human centrosomal kinase, Nek2, depends on an unusual leucine zipper dimerization motif

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205772

Regulating centrosomes by protein phosphorylation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205772

Abnormal centrosome amplification in the absence of p53.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205772

Overexpression of simian virus 40 small-T antigen blocks centrosome function and mitotic progression in human fibroblasts

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205772

Cell cycle regulation of the activity and subcellular localization of Plk1, a human protein kinase implicated in mitotic spindle function

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205772

A novel mammalian, mitotic spindle-associated kinase is related to yeast and fly chromosome segregation regulators

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205772

Centrosome hyperamplification in head and neck squamous cell carcinoma: a potential phenotypic marker of tumor aggressiveness

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205772

The p21 Cdk-interacting protein Cip1 is a potent inhibitor of G1 cyclin-dependent kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205772

Checkpoints: controls that ensure the order of cell cycle events

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205772

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205772

Requirement of Cdk2-cyclin E activity for repeated centrosome reproduction in Xenopus egg extracts

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205772

Requirement of a centrosomal activity for cell cycle progression through G1 into S phase

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205772

BRCA1 is associated with the centrosome during mitosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205772

Internalization of activated platelet-derived growth factor receptor-phosphatidylinositol-3' kinase complexes: potential interactions with the microtubule cytoskeleton

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205772

A mammalian cell cycle checkpoint pathway utilizing p53 and GADD45 is defective in ataxia-telangiectasia

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205772

Interaction and feedback regulation between STK15/BTAK/Aurora-A kinase and protein phosphatase 1 through mitotic cell division cycle

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205772

Sensitivity of the origin decision point to specific inhibitors of cellular signaling and metabolism

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205772

Centrosomes. Organizing cytoplasmic events.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205772

A high-affinity binding protein for the regulatory subunit of cAMP-dependent protein kinase II in the centrosome of human cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205772

Differential localization of protein kinase A type II isozymes in the Golgi-centrosomal area

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205772

Centrosomes enhance the fidelity of cytokinesis in vertebrates and are required for cell cycle progression

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205772

Cell cycle-dependent expression and spindle pole localization of a novel human protein kinase, Aik, related to Aurora of Drosophila and yeast Ipl1

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205772

Beyond self-assembly: from microtubules to morphogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205772

Casein kinase II is a predominantly nuclear enzyme

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205772

Centrosome abnormalities in human carcinomas of the gallbladder and intrahepatic and extrahepatic bile ducts.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205772

Cyclin-dependent kinase control of centrosome duplication

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205772

Genetic instability in colorectal cancers

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205772

Distinct intracellular localization of Lck and Fyn protein tyrosine kinases in human T lymphocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205772

Aneuploidy vs. gene mutation hypothesis of cancer: recent study claims mutation but is found to support aneuploidy

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205772

Centrosome amplification drives chromosomal instability in breast tumor development

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205772

Centrosome hypertrophy in human breast tumors: implications for genomic stability and cell polarity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205772

Altered centrosome structure is associated with abnormal mitoses in human breast tumors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205772

Phosphorylation of centrin during the cell cycle and its role in centriole separation preceding centrosome duplication

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205772

Cyclin-dependent kinase 2 (Cdk2) is required for centrosome duplication in mammalian cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205772

The centrosomal protein C-Nap1 is required for cell cycle-regulated centrosome cohesion

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205772

Aurora-A overexpression reveals tetraploidization as a major route to centrosome amplification in p53-/- cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205772

Centrosome duplication in mammalian somatic cells requires E2F and Cdk2-cyclin A.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205772

Association of centrosomal kinase STK15/BTAK mRNA expression with chromosomal instability in human breast cancers

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205772

p53 localizes to the centrosomes and spindles of mitotic cells in the embryonic chick epiblast, human cell lines, and a human primary culture: An immunofluorescence study

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205772

Mutant p53 and genomic instability in a transgenic mouse model of breast cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205772

Creative blocks: cell-cycle checkpoints and feedback controls

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205772

The C. elegans zyg-1 gene encodes a regulator of centrosome duplication with distinct maternal and paternal roles in the embryo

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205772

Ca2+/calmodulin-dependent protein kinase II: localization in the interphase nucleus and the mitotic apparatus of mammalian cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205772

Nucleophosmin/B23 is a target of CDK2/cyclin E in centrosome duplication

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205772

Centrosome-dependent exit of cytokinesis in animal cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205772

Four-dimensional control of the cell cycle

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205772

Cell cycle independent interaction of CDC2 with the centrosome, which is associated with the nuclear matrix-intermediate filament scaffold

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205772

Mitosis in a cell with multiple centrioles

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205772

Centrosome-centriole abnormalities are markers for abnormal cell divisions and cancer in the transgenic adenocarcinoma mouse prostate (TRAMP) model

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205772

Stepwise progression of centrosome defects associated with local tumor growth and metastatic process of human pancreatic carcinoma cells transplanted orthotopically into nude mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205772

The coordination of centrosome reproduction with nuclear events during the cell cycle

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205772

Direct regulation of the centrosome duplication cycle by the p53-p21Waf1/Cip1 pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205772

Difference in the centrosome duplication regulatory activity among p53 'hot spot' mutants: potential role of Ser 315 phosphorylation-dependent centrosome binding of p53.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205772

Specific phosphorylation of nucleophosmin on Thr(199) by cyclin-dependent kinase 2-cyclin E and its role in centrosome duplication.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205772

Control of microtubule dynamics and length by cyclin A- and cyclin B-dependent kinases in Xenopus egg extracts.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205772

Regulation of microtubule dynamics by cdc2 protein kinase in cell-free extracts of Xenopus eggs

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205772

GADD45 induction of a G2/M cell cycle checkpoint

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205772

Centrosome amplification as a possible mechanism for numerical chromosome aberrations in cerebral primitive neuroectodermal tumors with TP53 mutations

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205772

Cloning and characterization of a cDNA encoding an A-kinase anchoring protein located in the centrosome, AKAP450

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205772

A role for NIMA in the nuclear localization of cyclin B in Aspergillus nidulans

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205772

Centrosome amplification and a defective G2-M cell cycle checkpoint induce genetic instability in BRCA1 exon 11 isoform-deficient cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205772

Tumour amplified kinase STK15/BTAK induces centrosome amplification, aneuploidy and transformation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205772

Identification of major nucleolar proteins as candidate mitotic substrates of cdc2 kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205772

Centrosome abnormalities, genomic instability and carcinogenic progression

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205772

7 January 2021

Are centrosomes or aneuploidy the key to cancer?

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205772

7 January 2021

Chromosome number and structure both are markedly stable in RER colorectal cancers and are not destabilized by mutation of p53

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205772

7 January 2021

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205772

1 reference

7 January 2021

Centrosome amplification and instability occurs exclusively in aneuploid, but not in diploid colorectal cancer cell lines, and correlates with numerical chromosomal aberrations

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205772

7 January 2021

p53 is associated with cellular microtubules and is transported to the nucleus by dynein

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205772

7 January 2021

Genomic instability in Gadd45a-deficient mice

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205772

7 January 2021

Ultrastructural studies of a thymic carcinoid tumor

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205772

7 January 2021

Chromosomes, genes, and cancer

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205772

7 January 2021

Centrosome abnormalities, recurring deletions of chromosome 4, and genomic amplification of HER2/neu define mouse mammary gland adenocarcinomas induced by mutant HER2/neu

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205772

7 January 2021

Synergistic induction of centrosome hyperamplification by loss of p53 and cyclin E overexpression

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205772

7 January 2021

Effect of p53 on centrosome amplification in prostate cancer cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205772

7 January 2021

p34cdc2 kinase is localized to distinct domains within the mitotic apparatus

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205772

7 January 2021

The cdc2 kinase is a nuclear protein that is essential for mitosis in mammalian cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205772

7 January 2021

Microtubule nucleating capacity of centrosomes in tissue sections

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205772

7 January 2021

Correlation between centrosome abnormalities and chromosomal instability in human pancreatic cancer cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205772

7 January 2021

Electron microscopic investigation on cutaneous leiomyosarcoma (author's transl)

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205772

7 January 2021

Human papillomavirus infection, centrosome aberration, and genetic stability in cervical lesions

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205772

7 January 2021

The apparent linkage between centriole replication and the S phase of the cell cycle

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1205772

7 January 2021

Identifiers

DOI

10.1038/SJ.ONC.1205772

1 reference

PubMed ID

12214243

Dimensions Publication ID

4 August 2017

0 references

1 reference

PubMed ID

12214243