Bim mediates the elimination of functionally unfit Th1 responders from the memory pool. (Q34807146)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23840678%20AND%20SRC:MED&resulttype=core&format=json

4 March 2020

title

Bim mediates the elimination of functionally unfit Th1 responders from the memory pool (English)

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4 March 2020

3

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4 March 2020

author name string

David C Jay

series ordinal

1

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4 March 2020

Diana M Mitchell

series ordinal

2

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language of work or name

English

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publication date

28 June 2013

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4 March 2020

1 reference

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4 March 2020

volume

8

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issue

6

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4 March 2020

page(s)

e67363

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Creative Commons Attribution 4.0 International

4 March 2020

copyright license

start time

28 June 2013

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

cites work

Stability and function of secondary Th1 memory cells are dependent on the nature of the secondary stimulus.

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Opposing signals from the Bcl6 transcription factor and the interleukin-2 receptor generate T helper 1 central and effector memory cells.

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Apoptosis regulators Fas and Bim synergistically control T-lymphocyte homeostatic proliferation

8 July 2018

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8 July 2018

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Proapoptotic Bcl-2 family member Bim promotes persistent infection and limits protective immunity

8 July 2018

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8 July 2018

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Bim/Bcl-2 balance is critical for maintaining naive and memory T cell homeostasis

8 July 2018

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Multifunctional TH1 cells define a correlate of vaccine-mediated protection against Leishmania major

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Multiple-cytokine-producing antiviral CD4 T cells are functionally superior to single-cytokine-producing cells

8 July 2018

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Convergence of TCR and cytokine signaling leads to FOXO3a phosphorylation and drives the survival of CD4+ central memory T cells

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Role of Bim in regulating CD8+ T-cell responses during chronic viral infection.

8 July 2018

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Duration of the initial TCR stimulus controls the magnitude but not functionality of the CD8+ T cell response

8 July 2018

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Bim mediates apoptosis of CD127(lo) effector T cells and limits T cell memory

8 July 2018

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8 July 2018

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8 July 2018

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8 July 2018

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8 July 2018

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Shutdown of an acute T cell immune response to viral infection is mediated by the proapoptotic Bcl-2 homology 3-only protein Bim

8 July 2018

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BH3-only Bcl-2 family member Bim is required for apoptosis of autoreactive thymocytes

8 July 2018

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8 July 2018

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8 July 2018

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8 July 2018

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8 July 2018

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8 July 2018

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8 July 2018

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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26 October 2018

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12 December 2020

T cell fitness determined by signal strength

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12 December 2020

Dynamic programming of CD8+ T lymphocyte responses

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12 December 2020

Clonal selection of helper T cells is determined by an affinity threshold with no further skewing of TCR binding properties

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12 December 2020

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10.1371/JOURNAL.PONE.0067363

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4 March 2020

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4 March 2020

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