Impaired NMDA receptor transmission alters striatal synapses and DISC1 protein in an age-dependent manner. (Q34804839)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21436042%20AND%20SRC:MED&resulttype=core&format=json

26 January 2020

title

Impaired NMDA receptor transmission alters striatal synapses and DISC1 protein in an age-dependent manner (English)

1 reference

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26 January 2020

1 reference

1

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26 January 2020

Ana F Oliveira

3

1 reference

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26 January 2020

8

Ryohei Yasuda

1 reference

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26 January 2020

9

Marc G Caron

1 reference

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26 January 2020

author name string

Marija Milenkovic

2

1 reference

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26 January 2020

Yasmin Escobedo-Lozoya

4

1 reference

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26 January 2020

Saurav Seshadri

5

1 reference

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26 January 2020

Ali Salahpour

6

1 reference

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26 January 2020

Akira Sawa

7

1 reference

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26 January 2020

language of work or name

English

0 references

publication date

21 March 2011

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21436042%20AND%20SRC:MED&resulttype=core&format=json

Proceedings of the National Academy of Sciences of the United States of America

26 January 2020

published in

1 reference

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26 January 2020

volume

108

1 reference

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26 January 2020

issue

14

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26 January 2020

page(s)

5795-5800

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The psychiatric disease risk factors DISC1 and TNIK interact to regulate synapse composition and function.

26 January 2020

cites work

1 reference

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mTOR-dependent synapse formation underlies the rapid antidepressant effects of NMDA antagonists

8 July 2018

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Loss of GluN2B-containing NMDA receptors in CA1 hippocampus and cortex impairs long-term depression, reduces dendritic spine density, and disrupts learning

8 July 2018

1 reference

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NR1 knockdown mice as a representative model of the glutamate hypothesis of schizophrenia.

8 July 2018

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A possible role for the striatum in the pathogenesis of the cognitive symptoms of schizophrenia.

8 July 2018

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Knockdown of DISC1 by in utero gene transfer disturbs postnatal dopaminergic maturation in the frontal cortex and leads to adult behavioral deficits

8 July 2018

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Disrupted-in-Schizophrenia 1 (DISC1) regulates spines of the glutamate synapse via Rac1

8 July 2018

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Differential effects of prenatal and postnatal expressions of mutant human DISC1 on neurobehavioral phenotypes in transgenic mice: evidence for neurodevelopmental origin of major psychiatric disorders.

8 July 2018

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Postnatal NMDA receptor ablation in corticolimbic interneurons confers schizophrenia-like phenotypes

8 July 2018

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Understanding the role of DISC1 in psychiatric disease and during normal development

8 July 2018

1 reference

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Downregulation of NR3A-containing NMDARs is required for synapse maturation and memory consolidation.

8 July 2018

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Kalirin regulates cortical spine morphogenesis and disease-related behavioral phenotypes

8 July 2018

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Assessment of NMDA receptor NR1 subunit hypofunction in mice as a model for schizophrenia

8 July 2018

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Dendritic spine pathologies in hippocampal pyramidal neurons from Rett syndrome brain and after expression of Rett-associated MECP2 mutations

8 July 2018

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Reduced dendritic spine density in auditory cortex of subjects with schizophrenia

8 July 2018

1 reference

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A mutation in mouse Disc1 that models a schizophrenia risk allele leads to specific alterations in neuronal architecture and cognition

8 July 2018

1 reference

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Regulation of spine morphology and spine density by NMDA receptor signaling in vivo

8 July 2018

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The DISC locus in psychiatric illness

8 July 2018

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NMDA receptor trafficking in synaptic plasticity and neuropsychiatric disorders

8 July 2018

1 reference

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D1 and D2 dopamine-receptor modulation of striatal glutamatergic signaling in striatal medium spiny neurons

8 July 2018

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Anatomical and physiological plasticity of dendritic spines

8 July 2018

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DISC1 regulates the transport of the NUDEL/LIS1/14-3-3epsilon complex through kinesin-1

8 July 2018

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Disrupted in Schizophrenia 1 Interactome: evidence for the close connectivity of risk genes and a potential synaptic basis for schizophrenia

8 July 2018

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Disrupted motor learning and long-term synaptic plasticity in mice lacking NMDAR1 in the striatum

8 July 2018

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8 July 2018

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Cocaine-induced dendritic spine formation in D1 and D2 dopamine receptor-containing medium spiny neurons in nucleus accumbens

8 July 2018

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DISC1 and PDE4B are interacting genetic factors in schizophrenia that regulate cAMP signaling

8 July 2018

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8 July 2018

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Deficits in sensorimotor gating and tests of social behavior in a genetic model of reduced NMDA receptor function

8 July 2018

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8 July 2018

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8 July 2018

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Activity level controls postsynaptic composition and signaling via the ubiquitin-proteasome system

8 July 2018

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Associative memory formation increases the observation of dendritic spines in the hippocampus.

8 July 2018

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8 July 2018

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Dendritic spine structural anomalies in fragile-X mental retardation syndrome

8 July 2018

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8 July 2018

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Dopaminergic modulation of neuronal excitability in the striatum and nucleus accumbens

8 July 2018

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Enrichment induces structural changes and recovery from nonspatial memory deficits in CA1 NMDAR1-knockout mice

8 July 2018

1 reference

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Mice with reduced NMDA receptor expression display behaviors related to schizophrenia

8 July 2018

1 reference

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Reduced dendritic spine density on cerebral cortical pyramidal neurons in schizophrenia

8 July 2018

1 reference

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Increased NMDA current and spine density in mice lacking the NMDA receptor subunit NR3A

8 July 2018

1 reference

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Isolation and structural studies on synaptic complexes from rat brain

8 July 2018

1 reference

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Identification of candidate genes for psychosis in rat models, and possible association between schizophrenia and the 14-3-3eta gene

8 July 2018

1 reference

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Identification of YWHAE, a gene encoding 14-3-3epsilon, as a possible susceptibility gene for schizophrenia.

21 January 2018

1 reference

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Altered expression of 14-3-3 genes in the prefrontal cortex of subjects with schizophrenia.

21 January 2018

1 reference

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Assessing the role of endooligopeptidase activity of Ndel1 (nuclear-distribution gene E homolog like-1) in neurite outgrowth

21 January 2018

1 reference

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Transient and selective overexpression of dopamine D2 receptors in the striatum causes persistent abnormalities in prefrontal cortex functioning.

21 January 2018

1 reference

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26 October 2018

Identifiers

DOI

10.1073/PNAS.1012621108

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21436042%20AND%20SRC:MED&resulttype=core&format=json

26 January 2020

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21436042%20AND%20SRC:MED&resulttype=core&format=json

26 January 2020

1 reference