Proteolytic characteristics of cathepsin D related to the recognition and cleavage of its target proteins (Q34804706)

4 August 2017

title

Proteolytic characteristics of cathepsin D related to the recognition and cleavage of its target proteins (English)

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4 August 2017

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Huiying Sun

1

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4 August 2017

Xiaomin Lou

2

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4 August 2017

Qiang Shan

3

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4 August 2017

Ju Zhang

4

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4 August 2017

Xu Zhu

5

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4 August 2017

Jia Zhang

6

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4 August 2017

Yang Wang

7

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4 August 2017

Yingying Xie

8

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4 August 2017

Ningzhi Xu

9

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4 August 2017

Siqi Liu

10

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4 August 2017

language of work or name

English

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publication date

20 June 2013

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4 August 2017

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4 August 2017

volume

8

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4 August 2017

issue

6

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4 August 2017

page(s)

e65733

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Creative Commons Attribution 4.0 International

4 August 2017

copyright license

start time

20 June 2013

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

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cites work

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Cathepsin D Expression in Colorectal Cancer: From Proteomic Discovery through Validation Using Western Blotting, Immunohistochemistry, and Tissue Microarrays

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Cathepsin D primes caspase-8 activation by multiple intra-chain proteolysis

8 July 2018

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Cysteine Protease Cathepsins in Atherosclerosis and Abdominal Aortic Aneurysm

8 July 2018

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The Apaf-1-binding protein Aven is cleaved by Cathepsin D to unleash its anti-apoptotic potential

8 July 2018

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Inhibition of cathepsin B activity attenuates extracellular matrix degradation and inflammatory breast cancer invasion

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Proteolytic specificity of cathepsin D on bovine F-actin.

8 July 2018

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Lucanthone is a novel inhibitor of autophagy that induces cathepsin D-mediated apoptosis

8 July 2018

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Osteopontin is cleaved at multiple sites close to its integrin-binding motifs in milk and is a novel substrate for plasmin and cathepsin D.

8 July 2018

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Cathepsin D and eukaryotic translation elongation factor 1 as promising markers of cellular senescence

8 July 2018

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Cathepsin D expression level affects alpha-synuclein processing, aggregation, and toxicity in vivo.

8 July 2018

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Proteome-derived, database-searchable peptide libraries for identifying protease cleavage sites

8 July 2018

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Depletion of procathepsin D gene expression by RNA interference: a potential therapeutic target for breast cancer

8 July 2018

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Proteomic discovery of protease substrates

8 July 2018

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Serine protease cathepsin G regulates adhesion-dependent neutrophil effector functions by modulating integrin clustering

8 July 2018

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Cathepsin-L influences the expression of extracellular matrix in lymphoid organs and plays a role in the regulation of thymic output and of peripheral T cell number

8 July 2018

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Lysosomal Enzymes Are Released From Cultured Human Macrophages, Hydrolyze LDL In Vitro, and Are Present Extracellularly in Human Atherosclerotic Lesions

8 July 2018

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Down-regulation of cathepsin-D expression by antisense gene transfer inhibits tumor growth and experimental lung metastasis of human breast cancer cells.

8 July 2018

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Substrate specificity of human cathepsin D using internally quenched fluorescent peptides derived from reactive site loop of kallistatin

8 July 2018

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Proteolysis of human hemoglobin by schistosome cathepsin D.

8 July 2018

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Cytosolic proteolysis of tau by cathepsin D in hippocampus following suppression of cathepsins B and L.

8 July 2018

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Experimentally determined hydrophobicity scale for proteins at membrane interfaces

8 July 2018

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Mice deficient for the lysosomal proteinase cathepsin D exhibit progressive atrophy of the intestinal mucosa and profound destruction of lymphoid cells

8 July 2018

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Action of cathepsin D on fructose-1,6-bisphosphate aldolase

8 July 2018

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Sequence logos: a new way to display consensus sequences

8 July 2018

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Hydrophobicity indices for amino acid residues as determined by high-performance liquid chromatography.

8 July 2018

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Degradation of extracellular-matrix proteins by human cathepsin B from normal and tumour tissues

8 July 2018

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Cathepsin D cleaves aggrecan at unique sites within the interglobular domain and chondroitin sulfate attachment regions that are also cleaved when cartilage is maintained at acid pH.

8 July 2018

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https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0065733

Thrombin up-regulates cathepsin D which enhances angiogenesis, growth, and metastasis

21 January 2018

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https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0065733

Transition from atherosclerosis to aortic aneurysm in humans coincides with an increased expression of RAS components

21 January 2018

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Cleavage specificities of aspartic proteinases toward oxidized insulin B chain at different pH values

21 January 2018

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https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0065733

Cathepsin D is a good candidate for the specific release of a stable hemorphin from hemoglobin in vivo: VV-hemorphin-7.

21 January 2018

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https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0065733

A quantitative proteomics design for systematic identification of protease cleavage events.

21 January 2018

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https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0065733

Cathepsin D expression is decreased in Alzheimer's disease fibroblasts

21 January 2018

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https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0065733

A pH-dependent reversible conformational transition of the human transferrin receptor leads to self-association

21 January 2018

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12 December 2020

Increased cathepsin B activity in multiple sclerosis brain

1 reference

12 December 2020

The selectivity of cathepsin D suggests an involvement of the enzyme in the generation of T-cell epitopes

1 reference

12 December 2020

Lysosome-mediated apoptosis is associated with cathepsin D-specific processing of bid at Phe24, Trp48, and Phe183

1 reference

12 December 2020

Alpha1-antichymotrypsin and kallistatin hydrolysis by human cathepsin D

1 reference

12 December 2020

10.1371/JOURNAL.PONE.0065733

Identifiers

DOI

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4 August 2017

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4 August 2017

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