Protein kinase C changes in diabetes: is the concept relevant to neuropathy? (Q34800484)

4 August 2017

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title

Protein kinase C changes in diabetes: is the concept relevant to neuropathy? (English)

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4 August 2017

Joseph Eichberg

1

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4 August 2017

1 January 2002

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International Review of Neurobiology

4 August 2017

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4 August 2017

50

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4 August 2017

61-82

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Protein kinase C inhibitors decrease hyperalgesia and C-fiber hyperexcitability in the streptozotocin-diabetic rat.

4 August 2017

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2802%2950073-8

7 January 2021

Increased responsiveness of sensory neurons in the saphenous nerve of the streptozotocin-diabetic rat.

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2802%2950073-8

7 January 2021

A phorbol ester-sensitive kinase catalyzes the phosphorylation of P0 glycoprotein in myelin

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2802%2950073-8

7 January 2021

The relationship of vascular changes to metabolic factors in diabetes mellitus and their role in the development of peripheral nerve complications

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2802%2950073-8

7 January 2021

Effects of antioxidants on nerve and vascular dysfunction in experimental diabetes.

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2802%2950073-8

7 January 2021

Protein kinase C effects on nerve function, perfusion, Na(+), K(+)-ATPase activity and glutathione content in diabetic rats

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2802%2950073-8

7 January 2021

Nonesterified fatty acids in normal and diabetic rat sciatic nerve

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2802%2950073-8

7 January 2021

Protein kinase C is activated in glomeruli from streptozotocin diabetic rats. Possible mediation by glucose

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2802%2950073-8

7 January 2021

Protein kinase C-beta contributes to NADPH oxidase activation in neutrophils

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2802%2950073-8

7 January 2021

Effect of nerve growth factor treatment on p75NTR gene expression in lumbar dorsal root ganglia of streptozocin-induced diabetic rats

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2802%2950073-8

7 January 2021

Protein kinase C isozymes and the regulation of diverse cell responses

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2802%2950073-8

7 January 2021

The effect of intensive treatment of diabetes on the development and progression of long-term complications in insulin-dependent diabetes mellitus. The Diabetes Control and Complications Trial Research Group

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2802%2950073-8

7 January 2021

Key role for the epsilon isoform of protein kinase C in painful alcoholic neuropathy in the rat.

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2802%2950073-8

7 January 2021

Effects of hindlimb temperature on sciatic nerve laser Doppler vascular conductance in control and streptozotocin-diabetic rats

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2802%2950073-8

7 January 2021

Dual role of pseudosubstrate in the coordinated regulation of protein kinase C by phosphorylation and diacylglycerol

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2802%2950073-8

7 January 2021

Phosphorylation of myelin protein: recent advances

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2802%2950073-8

7 January 2021

Human recombinant nerve growth factor replaces deficient neurotrophic support in the diabetic rat

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2802%2950073-8

7 January 2021

Interaction of protein kinase C and cAMP-dependent pathways in the phosphorylation of the Na,K-ATPase

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2802%2950073-8

7 January 2021

Phosphorylation of Na,K-ATPase by protein kinase C at Ser18 occurs in intact cells but does not result in direct inhibition of ATP hydrolysis

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2802%2950073-8

7 January 2021

Glucose-induced changes in protein kinase C and nitric oxide are prevented by vitamin E

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2802%2950073-8

7 January 2021

The carboxyl terminus of protein kinase c provides a switch to regulate its interaction with the phosphoinositide-dependent kinase, PDK-1.

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2802%2950073-8

7 January 2021

Mapping of a molecular determinant for protein kinase C betaII isozyme function

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2802%2950073-8

7 January 2021

High glucose concentrations and protein kinase C isoforms in vascular smooth muscle cells.

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2802%2950073-8

7 January 2021

Inhibition of protein kinase C restores Na+,K(+)-ATPase activity in sciatic nerve of diabetic mice

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2802%2950073-8

7 January 2021

Mechanisms underlying endothelial dysfunction in diabetes mellitus

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2802%2950073-8

7 January 2021

Protein kinase C activation: isozyme-specific effects on metabolism and cardiovascular complications in diabetes

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2802%2950073-8

7 January 2021

Glucose or diabetes activates p38 mitogen-activated protein kinase via different pathways

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2802%2950073-8

7 January 2021

High glucose level and free fatty acid stimulate reactive oxygen species production through protein kinase C--dependent activation of NAD(P)H oxidase in cultured vascular cells

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2802%2950073-8

7 January 2021

Amelioration of vascular dysfunctions in diabetic rats by an oral PKC beta inhibitor

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2802%2950073-8

7 January 2021

Effects of the Diacylglycerol Complexing Agent, Cremophor, on Nerve-Conduction Velocity and Perfusion in Diabetic Rats

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2802%2950073-8

7 January 2021

(S)-13-[(dimethylamino)methyl]-10,11,14,15-tetrahydro-4,9:16, 21-dimetheno-1H, 13H-dibenzo[e,k]pyrrolo[3,4-h][1,4,13]oxadiazacyclohexadecene-1,3(2H)-d ione (LY333531) and related analogues: isozyme selective inhibitors of protein kinase C beta

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2802%2950073-8

7 January 2021

The C1 and C2 domains of protein kinase C are independent membrane targeting modules, with specificity for phosphatidylserine conferred by the C1 domain

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2802%2950073-8

7 January 2021

Differential expression of protein kinase C isoforms in streptozotocin-induced diabetic rats

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2802%2950073-8

7 January 2021

A novel nociceptor signaling pathway revealed in protein kinase C epsilon mutant mice

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2802%2950073-8

7 January 2021

The protein kinase C family: heterogeneity and its implications

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2802%2950073-8

7 January 2021

Alpha-lipoic acid: effect on glucose uptake, sorbitol pathway, and energy metabolism in experimental diabetic neuropathy

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2802%2950073-8

7 January 2021

Superoxide-induced stimulation of protein kinase C via thiol modification and modulation of zinc content

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2802%2950073-8

7 January 2021

Roles for beta II-protein kinase C and RACK1 in positive and negative signaling for superoxide anion generation in differentiated HL60 cells

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2802%2950073-8

7 January 2021

Abnormalities of retinal metabolism in diabetes or experimental galactosemia: V. Relationship between protein kinase C and ATPases.

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2802%2950073-8

7 January 2021

Amelioration of accelerated diabetic mesangial expansion by treatment with a PKC beta inhibitor in diabetic db/db mice, a rodent model for type 2 diabetes

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2802%2950073-8

7 January 2021

Protein kinase C activation and the development of diabetic complications

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2802%2950073-8

7 January 2021

d-Alpha-tocopherol prevents the hyperglycemia induced activation of diacylglycerol (DAG)-protein kinase C (PKC) pathway in vascular smooth muscle cell by an increase of DAG kinase activity

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2802%2950073-8

7 January 2021

Fatty acids modulate protein kinase C activation in porcine vascular smooth muscle cells independently of their effect on de novo diacylglycerol synthesis

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2802%2950073-8

7 January 2021

Mendenhall's syndrome: clues to the aetiology of human diabetic neuropathy

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2802%2950073-8

7 January 2021

The extended protein kinase C superfamily

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https://api.crossref.org/works/10.1016%2FS0074-7742%2802%2950073-8

7 January 2021

Mechanism of the apparent cooperativity in the interaction of protein kinase C with phosphatidylserine.

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2802%2950073-8

7 January 2021

Phosphatidylglycerol is a physiologic activator of nuclear protein kinase C

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2802%2950073-8

7 January 2021

Glucose-induced hyperproliferation of cultured rat aortic smooth muscle cells through polyol pathway hyperactivity

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2802%2950073-8

7 January 2021

A protein kinase C-beta-selective inhibitor ameliorates neural dysfunction in streptozotocin-induced diabetic rats

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2802%2950073-8

7 January 2021

Protein kinase C: structural and spatial regulation by phosphorylation, cofactors, and macromolecular interactions

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2802%2950073-8

7 January 2021

Normalizing mitochondrial superoxide production blocks three pathways of hyperglycaemic damage

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2802%2950073-8

7 January 2021

The role of protein kinase C in cell surface signal transduction and tumour promotion

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2802%2950073-8

7 January 2021

Alternations of diacylglycerol kinase in streptozotocin-induced diabetic rats

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2802%2950073-8

7 January 2021

Protein kinases C translocation responses to low concentrations of arachidonic acid

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2802%2950073-8

7 January 2021

Induction of endothelin-1 expression by glucose: an effect of protein kinase C activation

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https://api.crossref.org/works/10.1016%2FS0074-7742%2802%2950073-8

7 January 2021

Inhibition of protein kinase C--do we, can we, and should we?

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2802%2950073-8

7 January 2021

Protein kinase C isozyme expression in sciatic nerves and spinal cords of experimentally diabetic rats.

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2802%2950073-8

7 January 2021

The role of oxidative stress in the onset and progression of diabetes and its complications: a summary of a Congress Series sponsored by UNESCO-MCBN, the American Diabetes Association and the German Diabetes Society

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2802%2950073-8

7 January 2021

P0 phosphorylation in nerves from normal and diabetic rats: role of protein kinase C and turnover of phosphate groups

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2802%2950073-8

7 January 2021

Insulin-like growth factor-I prevents apoptosis in sympathetic neurons exposed to high glucose

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2802%2950073-8

7 January 2021

Neurons undergo apoptosis in animal and cell culture models of diabetes.

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2802%2950073-8

7 January 2021

Vascular endothelial growth factor expression in peripheral nerves and dorsal root ganglia in diabetic neuropathy in rats.

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2802%2950073-8

7 January 2021

Differences in sensitivity to hyperglycemic hypoxia of isolated rat sensory and motor nerve fibers

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2802%2950073-8

7 January 2021

Reversal of experimental diabetic neuropathy by VEGF gene transfer

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2802%2950073-8

7 January 2021

AGEs induce oxidative stress and activate protein kinase C-beta(II) in neonatal mesangial cells

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2802%2950073-8

7 January 2021

Diabetes induces selective alterations in the expression of protein kinase C isoforms in hepatocytes

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2802%2950073-8

7 January 2021

Mitogen-activated protein kinases as glucose transducers for diabetic complications

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2802%2950073-8

7 January 2021

Vitamin E suppresses diacylglycerol (DAG) level in thrombin-stimulated endothelial cells through an increase of DAG kinase activity

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2802%2950073-8

7 January 2021

Identification of PKC-isoform-specific biological actions using pharmacological approaches

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2802%2950073-8

7 January 2021

The role of protein kinase C in the development of the complications of diabetes

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2802%2950073-8

7 January 2021

Characterization of vascular endothelial growth factor's effect on the activation of protein kinase C, its isoforms, and endothelial cell growth

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2802%2950073-8

7 January 2021

Identification of the mechanism for the inhibition of Na+,K(+)-adenosine triphosphatase by hyperglycemia involving activation of protein kinase C and cytosolic phospholipase A2.

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2802%2950073-8

7 January 2021

Saturated non-esterified fatty acids stimulate de novo diacylglycerol synthesis and protein kinase c activity in cultured aortic smooth muscle cells

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2802%2950073-8

7 January 2021

1,2-diacylglycerol content and its arachidonyl-containing molecular species are reduced in sciatic nerve from streptozotocin-induced diabetic rats

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2802%2950073-8

7 January 2021

Diabetic neuropathies: features and mechanisms.

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2802%2950073-8

7 January 2021

Fatty acids inhibit growth-factor-induced diacylglycerol kinase alpha activation in vascular smooth-muscle cells

1 reference

https://api.crossref.org/works/10.1016%2FS0074-7742%2802%2950073-8

7 January 2021

10.1016/S0074-7742(02)50073-8

Identifiers

DOI

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4 August 2017

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PubMed ID

12198821