Nuclear endpoint of Wnt signaling: neoplastic transformation induced by transactivating lymphoid-enhancing factor 1. (Q34793950)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9874785%20AND%20SRC:MED&resulttype=core&format=json

8 December 2019

title

Nuclear endpoint of Wnt signaling: neoplastic transformation induced by transactivating lymphoid-enhancing factor 1 (English)

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8 December 2019

1

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8 December 2019

Andreas Hecht

2

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8 December 2019

Peter K. Vogt

5

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8 December 2019

author name string

U Kruse

3

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8 December 2019

R Kemler

4

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8 December 2019

language of work or name

English

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publication date

1 January 1999

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Proceedings of the National Academy of Sciences of the United States of America

8 December 2019

published in

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8 December 2019

volume

96

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8 December 2019

page(s)

139-144

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8 December 2019

issue

1

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The akt kinase: molecular determinants of oncogenicity

8 December 2019

cites work

1 reference

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Axin, an inhibitor of the Wnt signalling pathway, interacts with beta-catenin, GSK-3beta and APC and reduces the beta-catenin level

8 July 2018

1 reference

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Identification of c-MYC as a target of the APC pathway

8 July 2018

1 reference

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Downregulation of beta-catenin by human Axin and its association with the APC tumor suppressor, beta-catenin and GSK3 beta

8 July 2018

1 reference

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Axin, a negative regulator of the wnt signaling pathway, directly interacts with adenomatous polyposis coli and regulates the stabilization of beta-catenin

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=15106

Functional interaction of an axin homolog, conductin, with beta-catenin, APC, and GSK3beta

8 July 2018

1 reference

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Bridging of beta-catenin and glycogen synthase kinase-3beta by axin and inhibition of beta-catenin-mediated transcription

8 July 2018

1 reference

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Axin, a negative regulator of the Wnt signaling pathway, forms a complex with GSK-3beta and beta-catenin and promotes GSK-3beta-dependent phosphorylation of beta-catenin

8 July 2018

1 reference

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Wnt signaling: a common theme in animal development

8 July 2018

1 reference

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Hormone-regulatable neoplastic transformation induced by a Jun-estrogen receptor chimera

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=15106

Interaction and functional collaboration of p300 and C/EBPbeta

8 July 2018

1 reference

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Analysis of the signaling activities of localization mutants of beta-catenin during axis specification in Xenopus

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=15106

beta-catenin is a target for the ubiquitin-proteasome pathway

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=15106

A versatile transcriptional effector of Wingless signaling

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=15106

ALY, a context-dependent coactivator of LEF-1 and AML-1, is required for TCRalpha enhancer function

8 July 2018

1 reference

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Armadillo coactivates transcription driven by the product of the Drosophila segment polarity gene dTCF

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=15106

Stabilization of beta-catenin by genetic defects in melanoma cell lines

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=15106

Activation of beta-catenin-Tcf signaling in colon cancer by mutations in beta-catenin or APC

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=15106

Constitutive transcriptional activation by a beta-catenin-Tcf complex in APC-/- colon carcinoma

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=15106

A frizzled homolog functions in a vertebrate Wnt signaling pathway

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=15106

Nuclear localization of beta-catenin by interaction with transcription factor LEF-1

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=15106

Cadherin-catenin complex: protein interactions and their implications for cadherin function

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=15106

Functional interaction of beta-catenin with the transcription factor LEF-1

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=15106

XTcf-3 transcription factor mediates beta-catenin-induced axis formation in Xenopus embryos

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=15106

Deletion of an amino-terminal sequence beta-catenin in vivo and promotes hyperphosporylation of the adenomatous polyposis coli tumor suppressor protein

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=15106

A new member of the frizzled family from Drosophila functions as a Wingless receptor

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=15106

Wnt-1 regulates free pools of catenins and stabilizes APC-catenin complexes

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=15106

Cell adhesion: the molecular basis of tissue architecture and morphogenesis

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=15106

From cadherins to catenins: cytoplasmic protein interactions and regulation of cell adhesion

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=15106

LEF-1 contains an activation domain that stimulates transcription only in a specific context of factor-binding sites.

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=15106

Assembly and function of a TCR alpha enhancer complex is dependent on LEF-1-induced DNA bending and multiple protein-protein interactions

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=15106

Structural basis for DNA bending by the architectural transcription factor LEF-1

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=15106

New Procedure for DNA Transfection with Polycation and Dimethyl Sulfoxide

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=15106

Mode of proviral activation of a putative mammary oncogene (int-1) on mouse chromosome 15

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=15106

Many tumors induced by the mouse mammary tumor virus contain a provirus integrated in the same region of the host genome

8 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=15106

Cell-specific expression of the rat insulin gene: evidence for role of two distinct 5' flanking elements

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=15106

Functional dissection of VP16, the trans-activator of herpes simplex virus immediate early gene expression

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=15106

Purification of a RAS-responsive adenylyl cyclase complex from Saccharomyces cerevisiae by use of an epitope addition method

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=15106

Efficient transformation of chicken embryo fibroblasts by c-Jun requires structural modification in coding and noncoding sequences

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=15106

A thymus-specific member of the HMG protein family regulates the human T cell receptor C alpha enhancer

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=15106

Identification of a Gene Located at Chromosome 5q21 that Is Mutated in Colorectal Cancers

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=15106

LEF-1, a gene encoding a lymphoid-specific protein with an HMG domain, regulates T-cell receptor alpha enhancer function [corrected]

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=15106

Mutations of chromosome 5q21 genes in FAP and colorectal cancer patients

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=15106

Identification and characterization of the familial adenomatous polyposis coli gene

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=15106

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=15106

The HMG domain of lymphoid enhancer factor 1 bends DNA and facilitates assembly of functional nucleoprotein structures

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=15106

Somatic mutations of the APC gene in colorectal tumors: mutation cluster region in the APC gene

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=15106

Germ-line mutations of the APC gene in 53 familial adenomatous polyposis patients

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=15106

LEF-1, a nuclear factor coordinating signaling inputs from wingless and decapentaplegic.

8 July 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.96.1.139

pangolin encodes a Lef-1 homologue that acts downstream of Armadillo to transduce the Wingless signal in Drosophila.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.96.1.139

Induction of a beta-catenin-LEF-1 complex by wnt-1 and transforming mutants of beta-catenin

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.96.1.139

The hLEF/TCF-1 alpha HMG protein contains a context-dependent transcriptional activation domain that induces the TCR alpha enhancer in T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.96.1.139

The hormone-binding domains of the estrogen and glucocorticoid receptors contain an inducible transcription activation function

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/9874785

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1073/PNAS.96.1.139

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9874785%20AND%20SRC:MED&resulttype=core&format=json

8 December 2019

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9874785%20AND%20SRC:MED&resulttype=core&format=json

8 December 2019

1 reference