Drug evaluation in cardiomyocytes derived from human induced pluripotent stem cells carrying a long QT syndrome type 2 mutation (Q34793218)

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24 January 2020

title

Drug evaluation in cardiomyocytes derived from human induced pluripotent stem cells carrying a long QT syndrome type 2 mutation (English)

1 reference

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Human Induced Pluripotent Stem Cells

24 January 2020

main subject

1 reference

1 reference

7

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24 January 2020

author name string

Elena Matsa

1

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24 January 2020

Divya Rajamohan

2

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24 January 2020

Emily Dick

3

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24 January 2020

Lorraine Young

4

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24 January 2020

Ian Mellor

5

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24 January 2020

Andrew Staniforth

6

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24 January 2020

publication date

2 March 2011

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24 January 2020

published in

European Heart Journal

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24 January 2020

volume

32

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24 January 2020

page(s)

952-962

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24 January 2020

issue

8

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Modelling the long QT syndrome with induced pluripotent stem cells

24 January 2020

cites work

1 reference

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Two new protocols to enhance the production and isolation of human induced pluripotent stem cell lines

8 July 2018

1 reference

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Nicorandil normalizes prolonged repolarisation in the first transgenic rabbit model with Long-QT syndrome 1 both in vitro and in vivo

8 July 2018

1 reference

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Pore mutants of HERG and KvLQT1 downregulate the reciprocal currents in stable cell lines

8 July 2018

1 reference

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Patient-specific induced pluripotent stem-cell models for long-QT syndrome

8 July 2018

1 reference

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Revealing the structural basis of action of hERG potassium channel activators and blockers

8 July 2018

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The action potential and comparative pharmacology of stem cell-derived human cardiomyocytes

8 July 2018

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The role of the epinephrine test in the diagnosis and management of children suspected of having congenital long QT syndrome

8 July 2018

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Characterization of novel KCNH2 mutations in type 2 long QT syndrome manifesting as seizures

8 July 2018

1 reference

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hERG1 channel activators: a new anti-arrhythmic principle

8 July 2018

1 reference

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HERG-F463L potassium channels linked to long QT syndrome reduce I(Kr) current by a trafficking-deficient mechanism

8 July 2018

1 reference

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The QT syndromes: long and short

8 July 2018

1 reference

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Pharmacological approach to the treatment of long and short QT syndromes

8 July 2018

1 reference

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Induced pluripotent stem cell lines derived from human somatic cells

8 July 2018

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Inherited arrhythmias: a National Heart, Lung, and Blood Institute and Office of Rare Diseases workshop consensus report about the diagnosis, phenotyping, molecular mechanisms, and therapeutic approaches for primary cardiomyopathies of gene mutation

8 July 2018

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Transgenic enrichment of cardiomyocytes from human embryonic stem cells

8 July 2018

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Improved human embryonic stem cell embryoid body homogeneity and cardiomyocyte differentiation from a novel V-96 plate aggregation system highlights interline variability

8 July 2018

1 reference

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hERG potassium channels and cardiac arrhythmia

8 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3076668

Long QT syndrome presenting as epileptic seizures in an adult

8 July 2018

1 reference

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Ion channels: function unravelled by dysfunction

8 July 2018

1 reference

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Association of long QT syndrome loci and cardiac events among patients treated with beta-blockers.

8 July 2018

1 reference

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Postmortem molecular screening in unexplained sudden death.

8 July 2018

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Drug-induced prolongation of the QT interval

8 July 2018

1 reference

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Differentiation of human embryonic stem cells to cardiomyocytes: role of coculture with visceral endoderm-like cells

8 July 2018

1 reference

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Implantable cardioverter defibrillator in high-risk long QT syndrome patients

8 July 2018

1 reference

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Risk stratification in the long-QT syndrome.

8 July 2018

1 reference

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Increased risk of arrhythmic events in long-QT syndrome with mutations in the pore region of the human ether-a-go-go-related gene potassium channel

8 July 2018

1 reference

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Genotype-phenotype correlation in the long-QT syndrome: gene-specific triggers for life-threatening arrhythmias.

8 July 2018

1 reference

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Effectiveness and limitations of beta-blocker therapy in congenital long-QT syndrome.

8 July 2018

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A mutation in HERG associated with notched T waves in long QT syndrome.

8 July 2018

1 reference

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Idiopathic long QT syndrome: progress and questions

8 July 2018

1 reference

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Differential effects of beta-blockade on dispersion of repolarization in the absence and presence of sympathetic stimulation between the LQT1 and LQT2 forms of congenital long QT syndrome

8 July 2018

1 reference

Crossref

https://api.crossref.org/works/10.1093%2FEURHEARTJ%2FEHR073

Translational potential of human embryonic and induced pluripotent stem cells for myocardial repair: insights from experimental models

21 January 2018

1 reference

12 December 2020

Effects of a K(+) channel opener to reduce transmural dispersion of repolarization and prevent torsade de pointes in LQT1, LQT2, and LQT3 models of the long-QT syndrome

1 reference

12 December 2020

Cardiovascular and pharmacokinetic interactions between nicorandil and adjunctive propranolol, atenolol or diltiazem in conscious dogs

1 reference

12 December 2020

Characterization and culture of human embryonic stem cells

1 reference

12 December 2020

Clínica y genética en el síndrome de QT largo

1 reference

12 December 2020

Molecular genetics of long QT syndrome

1 reference

12 December 2020

Identifiers

DOI

10.1093/EURHEARTJ/EHR073

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21367833%20AND%20SRC:MED&resulttype=core&format=json

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24 January 2020

Fatcat ID

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Fatcat

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24 November 2022

mapped directly with Wikidata item

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24 January 2020

1 reference