Dual-specificity phosphatase 5 regulates nuclear ERK activity and suppresses skin cancer by inhibiting mutant Harvey-Ras (HRasQ61L)-driven SerpinB2 expression (Q34793029)

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English	Dual-specificity phosphatase 5 regulates nuclear ERK activity and suppresses skin cancer by inhibiting mutant Harvey-Ras (HRasQ61L)-driven SerpinB2 expression	scientific article

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scholarly article

1 reference

Europe PubMed Central

4 August 2017

Dual-specificity phosphatase 5 regulates nuclear ERK activity and suppresses skin cancer by inhibiting mutant Harvey-Ras (HRasQ61L)-driven SerpinB2 expression (English)

1 reference

Europe PubMed Central

4 August 2017

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Andrew M Kidger

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Andrew M Kidger

2

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Stephen M. Keyse

object named as

Stephen M Keyse

11

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author name string

Linda K Rushworth

1

1 reference

Europe PubMed Central

4 August 2017

Laurent Delavaine

3

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Europe PubMed Central

4 August 2017

Graeme Stewart

4

1 reference

Europe PubMed Central

4 August 2017

Susanne van Schelven

5

1 reference

Europe PubMed Central

4 August 2017

Jane Davidson

6

1 reference

Europe PubMed Central

4 August 2017

Christopher J Bryant

7

1 reference

Europe PubMed Central

4 August 2017

Edward Caddye

8

1 reference

Europe PubMed Central

4 August 2017

Philip East

9

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Europe PubMed Central

4 August 2017

Christopher J Caunt

10

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Europe PubMed Central

4 August 2017

language of work or name

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publication date

8 December 2014

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Europe PubMed Central

4 August 2017

Proceedings of the National Academy of Sciences of the United States of America

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Europe PubMed Central

4 August 2017

111

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Europe PubMed Central

4 August 2017

51

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Europe PubMed Central

4 August 2017

18267-18272

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Europe PubMed Central

4 August 2017

EGR1 decreases the malignancy of human non-small cell lung carcinoma by regulating KRT18 expression

1 reference

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8 July 2018

Tumor cell-expressed SerpinB2 is present on microparticles and inhibits metastasis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4280588

8 July 2018

Serpins promote cancer cell survival and vascular co-option in brain metastasis

1 reference

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8 July 2018

ERKs in cancer: friends or foes?

1 reference

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TLR-induced PAI-2 expression suppresses IL-1β processing via increasing autophagy and NLRP3 degradation

1 reference

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Tumor suppressor activity of the ERK/MAPK pathway by promoting selective protein degradation

1 reference

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The transcription factor C/EBP-β mediates constitutive and LPS-inducible transcription of murine SerpinB2.

1 reference

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Identification of mutant K-Ras-dependent phenotypes using a panel of isogenic cell lines

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Dual-specificity MAP kinase phosphatases (MKPs): shaping the outcome of MAP kinase signalling

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EGR1 and the ERK-ERF axis drive mammary cell migration in response to EGF.

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Human papilloma virus transformed CaSki cells constitutively express high levels of functional SerpinB2.

1 reference

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RAS mutations affect tumor necrosis factor-induced apoptosis in colon carcinoma cells via ERK-modulatory negative and positive feedback circuits along with non-ERK pathway effects

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Multi-stage chemical carcinogenesis in mouse skin: fundamentals and applications

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Identification of direct transcriptional targets of (V600E)BRAF/MEK signalling in melanoma

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Regulation of the inducible nuclear dual-specificity phosphatase DUSP5 by ERK MAPK.

1 reference

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(V600E)BRAF is associated with disabled feedback inhibition of RAF-MEK signaling and elevated transcriptional output of the pathway

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Revisiting the biological roles of PAI2 (SERPINB2) in cancer

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Dual-specificity MAP kinase phosphatases (MKPs) and cancer

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Targeting the Raf-MEK-ERK mitogen-activated protein kinase cascade for the treatment of cancer

1 reference

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MAP kinase signalling pathways in cancer

1 reference

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Differential regulation of MAP kinase signalling by dual-specificity protein phosphatases.

1 reference

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Targeting dual-specificity phosphatases: manipulating MAP kinase signalling and immune responses.

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Evidence for serpinB2-independent protection from TNF-alpha-induced apoptosis

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Specific inactivation and nuclear anchoring of extracellular signal-regulated kinase 2 by the inducible dual-specificity protein phosphatase DUSP5

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Down-regulation of dual-specificity phosphatase 5 in gastric cancer by promoter CpG island hypermethylation and its potential role in carcinogenesis

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SerpinB2 protection of retinoblastoma protein from calpain enhances tumor cell survival

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Identifiers

10.1073/PNAS.1420159112

1 reference

Europe PubMed Central

4 August 2017

2014PNAS..11118267R

0 references

1 reference

Europe PubMed Central

4 August 2017

1 reference

Europe PubMed Central

4 August 2017

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