Epigenetic versus genetic alterations in the inactivation of E-cadherin (Q34793012)

4 August 2017

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title

Epigenetic versus genetic alterations in the inactivation of E-cadherin (English)

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4 August 2017

Gordon Strathdee

1

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language of work or name

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1 October 2002

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Seminars in Cancer Biology

4 August 2017

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4 August 2017

12

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4 August 2017

373-379

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4 August 2017

5

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A genetic model for colorectal tumorigenesis

4 August 2017

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900057-3

7 January 2021

https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900057-3

1 reference

7 January 2021

Methylation-induced repression--belts, braces, and chromatin

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900057-3

7 January 2021

Aberrant CpG-island methylation has non-random and tumour-type-specific patterns.

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900057-3

7 January 2021

Aging, DNA methylation and cancer

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900057-3

7 January 2021

Inactivation of the E-cadherin-mediated cell adhesion system in human cancers

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900057-3

7 January 2021

Mutations of the human E-cadherin (CDH1) gene.

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900057-3

7 January 2021

Cadherin-catenin complex: Protein interactions and their implications for cadherin function

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900057-3

7 January 2021

The role of the cell-adhesion molecule E-cadherin as a tumour-suppressor gene

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900057-3

7 January 2021

E-cadherin-mediated cell-cell adhesion prevents invasiveness of human carcinoma cells

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900057-3

7 January 2021

Genetic manipulation of E-cadherin expression by epithelial tumor cells reveals an invasion suppressor role

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900057-3

7 January 2021

E-cadherin germline mutations in familial gastric cancer.

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900057-3

7 January 2021

Carcinogenesis: a balance between beta-catenin and APC.

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900057-3

7 January 2021

Regional assignment of the human loci for uvomorulin (UVO) and chymotrypsinogen B (CTRB) with the help of two overlapping deletions on the long arm of chromosome 16

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900057-3

7 January 2021

Mutations of the E-cadherin gene in human gynecologic cancers.

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900057-3

7 January 2021

Point mutation of the E-cadherin gene in invasive lobular carcinoma of the breast.

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900057-3

7 January 2021

E-cadherin gene mutations in signet ring cell carcinoma of the stomach

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900057-3

7 January 2021

E-cadherin inactivation in lobular carcinoma in situ of the breast: an early event in tumorigenesis

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900057-3

7 January 2021

E-cadherin germline mutations define an inherited cancer syndrome dominated by diffuse gastric cancer

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900057-3

7 January 2021

Silencing of the E-cadherin invasion-suppressor gene by CpG methylation in human carcinomas

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900057-3

7 January 2021

Methylation of the CDH1 promoter as the second genetic hit in hereditary diffuse gastric cancer

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900057-3

7 January 2021

Methylation of the E-cadherin gene in bladder neoplasia and in normal urothelial epithelium from elderly individuals

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900057-3

7 January 2021

E-cadherin regulates anchorage-independent growth and survival in oral squamous cell carcinoma cells

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900057-3

7 January 2021

Dependence of transcriptional repression on CpG methylation density

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900057-3

7 January 2021

Mechanisms of inactivation of E-cadherin in breast carcinoma: modification of the two-hit hypothesis of tumor suppressor gene

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900057-3

7 January 2021

Re-expression of E-cadherin, alpha-catenin and beta-catenin, but not of gamma-catenin, in metastatic tissue from breast cancer patients [seecomments]

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900057-3

7 January 2021

Methylation patterns of the E-cadherin 5' CpG island are unstable and reflect the dynamic, heterogeneous loss of E-cadherin expression during metastatic progression

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900057-3

7 January 2021

The transcription factor snail controls epithelial-mesenchymal transitions by repressing E-cadherin expression

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900057-3

7 January 2021

The transcription factor snail is a repressor of E-cadherin gene expression in epithelial tumour cells

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900057-3

7 January 2021

Molecular characterization of undifferentiated-type gastric carcinoma

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900057-3

7 January 2021

Inactivation of the E-cadherin gene in primary gastric carcinomas and gastric carcinoma cell lines

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900057-3

7 January 2021

E-Cadherin gene promoter hypermethylation in primary human gastric carcinomas

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900057-3

7 January 2021

Multiple ways of silencing E-cadherin gene expression in lobular carcinoma of the breast

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900057-3

7 January 2021

Chromosome alterations and E-cadherin gene mutations in human lobular breast cancer

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900057-3

7 January 2021

Altered expression of E-cadherin in breast cancer

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900057-3

7 January 2021

Epithelial-cadherin gene is not mutated in ductal carcinomas of the breast.

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900057-3

7 January 2021

Loss of immunohistochemical E-cadherin expression in colon cancer is not due to structural gene alterations

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900057-3

7 January 2021

Hypermethylation of the promoter region of the E-cadherin gene (CDH1) in sporadic and ulcerative colitis associated colorectal cancer

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900057-3

7 January 2021

A comparison of the genetic pathways involved in the pathogenesis of three types of colorectal cancer.

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900057-3

7 January 2021

Genetic mapping and DNA sequence-based analysis of deleted regions on chromosome 16 involved in progression of bladder cancer from occult preneoplastic conditions to invasive disease

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900057-3

7 January 2021

Loss of heterozygosity in childhood de novo acute myelogenous leukemia

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900057-3

7 January 2021

E-cadherin gene mutations are rare in adenocarcinomas of the oesophagus

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900057-3

7 January 2021

E-cadherin expression is commonly downregulated by CpG island hypermethylation in esophageal carcinoma cells

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900057-3

7 January 2021

Genetic aberration in primary hepatocellular carcinoma: correlation between p53 gene mutation and loss-of-heterozygosity on chromosome 16q21-q23 and 9p21-p23

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900057-3

7 January 2021

Aberrant DNA methylation precedes loss of heterozygosity on chromosome 16 in chronic hepatitis and liver cirrhosis

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900057-3

7 January 2021

E-cadherin gene mutations frequently occur in synovial sarcoma as a determinant of histological features

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900057-3

7 January 2021

Abnormalities of the E-cadherin/catenin adhesion complex in classical papillary thyroid carcinoma and in its diffuse sclerosing variant

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900057-3

7 January 2021

E-cadherin gene alterations are rare events in thyroid tumors

1 reference

https://api.crossref.org/works/10.1016%2FS1044-579X%2802%2900057-3

7 January 2021

10.1016/S1044-579X(02)00057-3

Identifiers

DOI

1 reference

4 August 2017

1 reference

PubMed ID

12191636