The antipsychotic potential of l-stepholidine--a naturally occurring dopamine receptor D1 agonist and D2 antagonist (Q34784192)

4 August 2017

The antipsychotic potential of l-stepholidine--a naturally occurring dopamine receptor D1 agonist and D2 antagonist (English)

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4 August 2017

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Sridhar Natesan

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David C Mamo

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object named as

David Mamo

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Greg E Reckless

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Karen B L Barlow

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John Odontiadis

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José N Nobrega

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Glen B Baker

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Susan R George

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3 June 2008

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inferred from page(s)

published in

Psychopharmacology

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4 August 2017

199

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2

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275-289

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https://scigraph.springernature.com/pub.10.1007/s00213-008-1172-1

4 August 2017

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cites work

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Dual actions of (-)-stepholidine on dopamine receptor subtypes after substantia nigra lesion

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D(1) receptors in prefrontal cells and circuits

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(-)-Stepholidine: a potential novel antipsychotic drug with dual D1 receptor agonist and D2 receptor antagonist actions

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GTP regulation of (-)-stepholidine binding to R(H) of D1 dopamine receptors in calf striatum.

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Statistical moments in pharmacokinetics.

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The impact of P-glycoprotein on the disposition of drugs targeted for indications of the central nervous system: evaluation using the MDR1A/1B knockout mouse model

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Do we still believe in the dopamine hypothesis? New data bring new evidence

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Stepholidine protects against H2O2 neurotoxicity in rat cortical neurons by activation of Akt.

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Do novel antipsychotics have similar pharmacological characteristics? A review of the evidence

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Pharmacokinetics and autoradiography of [3H] or [14C]stepholidine.

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Reversal of antipsychotic-induced working memory deficits by short-term dopamine D1 receptor stimulation

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Differential activation of adenylate cyclase and receptor internalization by novel dopamine D1 receptor agonists

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D1 and D2 dopamine receptors form heterooligomers and cointernalize after selective activation of either receptor

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12 December 2020

Increased phosphorylation of DARPP-32 by D1 agonistic action of l-stepholidine in the 6-OHDA-lesioned rat striatum.

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12 December 2020

Feed-back regulation of presynaptic D2 receptors blockaded by l-stepholidine and l-tetrahydropalmatine

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12 December 2020

Induction patterns of Fos-like immunoreactivity in the forebrain as predictors of atypical antipsychotic activity

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12 December 2020

Quantification of l-stepholidine in rat brain and plasma by high performance liquid chromatography combined with fluorescence detection.

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12 December 2020

Ethological resolution of behavioral topography and D2-like vs. D1-like agonist responses in congenic D4 dopamine receptor "knockouts": identification of D4:D1-like interactions

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The neuropsychopharmacology of phencyclidine: from NMDA receptor hypofunction to the dopamine hypothesis of schizophrenia

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(-)-Stepholidine promotes proliferation and neuronal differentiation of rat embryonic striatal precursor cells in vitro

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Antipsychotic dosing in preclinical models is often unrepresentative of the clinical condition: a suggested solution based on in vivo occupancy

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Dual actions of (-)-stepholidine on the dopamine receptor-mediated adenylate cyclase activity in rat corpus striatum

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D1-D2 dopamine receptor heterooligomers with unique pharmacology are coupled to rapid activation of Gq/11 in the striatum

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Ethological resolution of behavioural topography and D1-like versus D2-like agonist responses in congenic D5 dopamine receptor mutants: identification of D5:D2-like interactions.

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12 December 2020

Intra-prefrontal cortex injections of SCH 23390 influence nucleus accumbens dopamine levels 24 h post-infusion

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12 December 2020

Effect of (-)-stepholidine on serum prolactin level of female rats

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12 December 2020

Neuropharmacological effects of (-)-stepholidine and its analogues on brain dopaminergic system

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12 December 2020

Partial and full dopamine D1 receptor agonists in mice and rats: relation between behavioural effects and stimulation of adenylate cyclase activity in vitro

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12 December 2020

Involvement of receptor reserve in D1 agonistic action of (-)-stepholidine in lesioned rats.

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12 December 2020

Effects of (-)stepholidine in animal models for schizophrenia

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12 December 2020

10.1007/S00213-008-1172-1

Identifiers

DOI

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Dimensions Publication ID

4 August 2017

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