Current frontiers in clinical research application of MALDI imaging mass spectrometry (Q34777079)

4 August 2017

Current frontiers in clinical research application of MALDI imaging mass spectrometry (English)

1 reference

matrix-assisted laser desorption/ionization

4 August 2017

0 references

author name string

Patrick Neubert

series ordinal

1

1 reference

PubMed ID

23777216

4 August 2017

Axel Walch

series ordinal

2

1 reference

4 August 2017

1 June 2013

1 reference

Expert Review of Proteomics

4 August 2017

1 reference

4 August 2017

10

1 reference

4 August 2017

259-273

1 reference

4 August 2017

3

1 reference

Influence of the wavelength in high-irradiance ultraviolet laser desorption mass spectrometry of organic molecules

4 August 2017

1 reference

Molecular imaging of biological samples: localization of peptides and proteins using MALDI-TOF MS.

21 January 2018

1 reference

Mass spectrometry sampling under ambient conditions with desorption electrospray ionization

21 January 2018

1 reference

Ambient mass spectrometry for the intraoperative molecular diagnosis of human brain tumors.

21 January 2018

1 reference

High-resolution matrix-assisted laser desorption/ionization imaging of tryptic peptides from tissue

21 January 2018

1 reference

High-speed MALDI-TOF imaging mass spectrometry: rapid ion image acquisition and considerations for next generation instrumentation

21 January 2018

1 reference

Molecular mass spectrometry imaging in biomedical and life science research.

21 January 2018

1 reference

Normalization in MALDI-TOF imaging datasets of proteins: practical considerations

21 January 2018

1 reference

Molecular characterization of Wilms' tumor from a resource-constrained region of sub-Saharan Africa

21 January 2018

1 reference

Imaging mass spectrometry in biomarker discovery and validation

21 January 2018

1 reference

Approaching MALDI molecular imaging for clinical proteomic research: current state and fields of application

21 January 2018

1 reference

Imaging mass spectrometry statistical analysis

21 January 2018

1 reference

MALDI imaging mass spectrometry of human tissue: method challenges and clinical perspectives

21 January 2018

1 reference

Classification of HER2/neu status in gastric cancer using a breast-cancer derived proteome classifier

21 January 2018

1 reference

Novel molecular tumour classification using MALDI-mass spectrometry imaging of tissue micro-array

21 January 2018

1 reference

Protein signatures for survival and recurrence in metastatic melanoma

21 January 2018

1 reference

Mass spectrometric analysis of formalin-fixed paraffin-embedded tissue: unlocking the proteome within

21 January 2018

1 reference

Direct tissue analysis using matrix-assisted laser desorption/ionization mass spectrometry: practical aspects of sample preparation

21 January 2018

1 reference

Poly[N-(2-hydroxypropyl)methacrylamide]-based tissue-embedding medium compatible with MALDI mass spectrometry imaging experiments

21 January 2018

1 reference

MALDI imaging mass spectrometry for direct tissue analysis: technological advancements and recent applications

21 January 2018

1 reference

MALDI imaging mass spectrometry for direct tissue analysis: a new frontier for molecular histology

21 January 2018

1 reference

Peptide and protein imaging mass spectrometry in cancer research

21 January 2018

1 reference

Integrating histology and imaging mass spectrometry

21 January 2018

1 reference

A novel histology-directed strategy for MALDI-MS tissue profiling that improves throughput and cellular specificity in human breast cancer.

21 January 2018

1 reference

Enhancement of protein sensitivity for MALDI imaging mass spectrometry after chemical treatment of tissue sections

21 January 2018

1 reference

Orthogonal organic and aqueous-based washes of tissue sections to enhance protein sensitivity by MALDI imaging mass spectrometry.

21 January 2018

1 reference

Detergent enhancement of on-tissue protein analysis by matrix-assisted laser desorption/ionization imaging mass spectrometry

21 January 2018

1 reference

Controlled-pH tissue cleanup protocol for signal enhancement of small molecule drugs analyzed by MALDI-MS imaging

21 January 2018

1 reference

Liquid ionic matrixes for MALDI mass spectrometry imaging of lipids

21 January 2018

1 reference

Sample preparation for mass spectrometry imaging: small mistakes can lead to big consequences

21 January 2018

1 reference

Binary matrix for MALDI imaging mass spectrometry of phospholipids in both ion modes.

21 January 2018

1 reference

The effect of the mobile phase additives on sensitivity in the analysis of peptides and proteins by high-performance liquid chromatography-electrospray mass spectrometry.

21 January 2018

1 reference

A concise review of mass spectrometry imaging.

21 January 2018

1 reference

Sublimation as a method of matrix application for mass spectrometric imaging

21 January 2018

1 reference

Comparison between vacuum sublimed matrices and conventional dried droplet preparation in MALDI-TOF mass spectrometry

21 January 2018

1 reference

Sublimation of new matrix candidates for high spatial resolution imaging mass spectrometry of lipids: enhanced information in both positive and negative polarities after 1,5-diaminonapthalene deposition

21 January 2018

1 reference

A solvent-free matrix application method for matrix-assisted laser desorption/ionization imaging of small molecules.

21 January 2018

1 reference

Use of a solvent-free dry matrix coating for quantitative matrix-assisted laser desorption ionization imaging of 4-bromophenyl-1,4-diazabicyclo(3.2.2)nonane-4-carboxylate in rat brain and quantitative analysis of the drug from laser [...]

21 January 2018

1 reference

Proteomic analysis of formalin-fixed paraffin-embedded tissue by MALDI imaging mass spectrometry

21 January 2018

1 reference

Imaging mass spectrometry data reduction: automated feature identification and extraction

21 January 2018

1 reference

Tutorial: multivariate statistical treatment of imaging data for clinical biomarker discovery

21 January 2018

1 reference

MALDI imaging combined with hierarchical clustering as a new tool for the interpretation of complex human cancers

21 January 2018

1 reference

Proteomics pipeline for biomarker discovery of laser capture microdissected breast cancer tissue

21 January 2018

1 reference

NanoLC-FT-ICR MS improves proteome coverage attainable for approximately 3000 laser-microdissected breast carcinoma cells

21 January 2018

1 reference

Phosphopeptide enrichment with stable spatial coordination on a titanium dioxide coated glass slide

21 January 2018

1 reference

Early changes in protein expression detected by mass spectrometry predict tumor response to molecular therapeutics

21 January 2018

1 reference

Molecular profiling of experimental Parkinson's disease: direct analysis of peptides and proteins on brain tissue sections by MALDI mass spectrometry

21 January 2018

1 reference

Identifying proteins using matrix-assisted laser desorption/ionization in-source fragmentation data combined with database searching

21 January 2018

1 reference

T3-sequencing: targeted characterization of the N- and C-termini of undigested proteins by mass spectrometry

21 January 2018

1 reference

Rational selection of the optimum MALDI matrix for top-down proteomics by in-source decay

21 January 2018

1 reference

Selected protein monitoring in histological sections by targeted MALDI-FTICR in-source decay imaging

21 January 2018

1 reference

Multivariate analyses for biomarkers hunting and validation through on-tissue bottom-up or in-source decay in MALDI-MSI: application to prostate cancer

21 January 2018

1 reference

MALDI-in source decay applied to mass spectrometry imaging: a new tool for protein identification

21 January 2018

1 reference

Classification of HER2 receptor status in breast cancer tissues by MALDI imaging mass spectrometry

21 January 2018

1 reference

Tryptic peptide reference data sets for MALDI imaging mass spectrometry on formalin-fixed ovarian cancer tissues.

21 January 2018

1 reference

Internal calibrants allow high accuracy peptide matching between MALDI imaging MS and LC-MS/MS.

21 January 2018

1 reference

MALDI-ion mobility separation-mass spectrometry imaging of glucose-regulated protein 78 kDa (Grp78) in human formalin-fixed, paraffin-embedded pancreatic adenocarcinoma tissue sections.

21 January 2018

1 reference

High-throughput proteomic analysis of formalin-fixed paraffin-embedded tissue microarrays using MALDI imaging mass spectrometry

21 January 2018

1 reference

Detergent addition to tryptic digests and ion mobility separation prior to MS/MS improves peptide yield and protein identification for in situ proteomic investigation of frozen and formalin-fixed paraffin-embedded adenocarcinoma tissue sections

21 January 2018

1 reference

On-tissue protein identification and imaging by MALDI-ion mobility mass spectrometry.

21 January 2018

1 reference

MALDI imaging mass spectrometry for in situ proteomic analysis of preneoplastic lesions in pancreatic cancer

21 January 2018

1 reference

Development of liquid microjunction extraction strategy for improving protein identification from tissue sections.

21 January 2018

1 reference

Quantitative mass spectrometry imaging of propranolol and olanzapine using tissue extinction calculation as normalization factor

21 January 2018

1 reference

Imaging of a beta-peptide distribution in whole-body mice sections by MALDI mass spectrometry

21 January 2018

1 reference

Visualization of the cell-selective distribution of PUFA-containing phosphatidylcholines in mouse brain by imaging mass spectrometry

21 January 2018

1 reference

Quantitative analysis of pharmaceutical drug distribution in multiple organs by imaging mass spectrometry

21 January 2018

1 reference

Quantitative MALDI-MS(n) analysis of cocaine in the autopsied brain of a human cocaine user employing a wide isolation window and internal standards

21 January 2018

1 reference

Exploring three-dimensional matrix-assisted laser desorption/ionization imaging mass spectrometry data: three-dimensional spatial segmentation of mouse kidney

21 January 2018

1 reference

Integrating spatially resolved three-dimensional MALDI IMS with in vivo magnetic resonance imaging

21 January 2018

1 reference

Imaging mass spectrometry of proteins and peptides: 3D volume reconstruction

21 January 2018

1 reference

Fiducial markers for combined 3-dimensional mass spectrometric and optical tissue imaging.

21 January 2018

1 reference

3D imaging by mass spectrometry: a new frontier

21 January 2018

1 reference

Three-dimensional visualization of protein expression in mouse brain structures using imaging mass spectrometry.

21 January 2018

1 reference

3'-Deoxy-3'-18F-fluorothymidine PET predicts response to (V600E)BRAF-targeted therapy in preclinical models of colorectal cancer

21 January 2018

1 reference

Qualitative and quantitative MALDI imaging of the positron emission tomography ligands raclopride (a D2 dopamine antagonist) and SCH 23390 (a D1 dopamine antagonist) in rat brain tissue sections using a solvent-free dry matrix application method

21 January 2018

1 reference

Drug-based optical agents: infiltrating clinics at lower risk

21 January 2018

1 reference

Protein profiling in brain tumors using mass spectrometry: feasibility of a new technique for the analysis of protein expression

21 January 2018

1 reference

Imaging mass spectrometry of a specific fragment of mitogen-activated protein kinase/extracellular signal-regulated kinase kinase kinase 2 discriminates cancer from uninvolved prostate tissue.

21 January 2018

1 reference

Direct molecular tissue analysis by MALDI imaging mass spectrometry in the field of gastrointestinal disease

21 January 2018

1 reference

MALDI imaging mass spectrometry reveals COX7A2, TAGLN2 and S100-A10 as novel prognostic markers in Barrett's adenocarcinoma

21 January 2018

1 reference

MALDI imaging identifies prognostic seven-protein signature of novel tissue markers in intestinal-type gastric cancer

21 January 2018

1 reference

Molecular imaging of amyloid beta peptides in mouse brain sections using mass spectrometry

21 January 2018

1 reference

Mammalian heart renewal by pre-existing cardiomyocytes

21 January 2018

1 reference

Proteomic patterns of tumour subsets in non-small-cell lung cancer

21 January 2018

1 reference

S100-A10, thioredoxin, and S100-A6 as biomarkers of papillary thyroid carcinoma with lymph node metastasis identified by MALDI imaging.

21 January 2018

1 reference

Identification of markers of taxane sensitivity using proteomic and genomic analyses of breast tumors from patients receiving neoadjuvant paclitaxel and radiation.

21 January 2018

1 reference

Investigation of protein induction in tumour vascular targeted strategies by MALDI MSI.

21 January 2018

1 reference

Tumor classification of six common cancer types based on proteomic profiling by MALDI imaging.

21 January 2018

1 reference

Gastric cancer-specific protein profile identified using endoscopic biopsy samples via MALDI mass spectrometry

21 January 2018

1 reference

Proteomic tissue profiling for the improvement of grading of noninvasive papillary urothelial neoplasia

21 January 2018

1 reference

Application of MALDI imaging for the diagnosis of classical Hodgkin lymphoma

21 January 2018

1 reference

Imaging mass spectrometry of gastric carcinoma in formalin-fixed paraffin-embedded tissue microarray.

21 January 2018

1 reference

Imaging mass spectrometry of myxoid sarcomas identifies proteins and lipids specific to tumour type and grade, and reveals biochemical intratumour heterogeneity

21 January 2018

1 reference

Multiple statistical analysis techniques corroborate intratumor heterogeneity in imaging mass spectrometry datasets of myxofibrosarcoma

21 January 2018

1 reference

Intratumor Heterogeneity and Branched Evolution Revealed by Multiregion Sequencing

21 January 2018

1 reference

Mass spectrometry imaging for drug distribution studies

21 January 2018

1 reference

MALDI imaging mass spectrometry: bridging biology and chemistry in drug development

21 January 2018

1 reference

Mass spectrometry imaging is moving toward drug protein co-localization.

21 January 2018

1 reference

Specific MALDI Imaging and Profiling for Biomarker Hunting and Validation: Fragment of the 11S Proteasome Activator Complex, Reg Alpha Fragment, Is a New Potential Ovary Cancer Biomarker

21 January 2018

1 reference

21 January 2018

Identifiers

DOI

10.1586/EPR.13.19

1 reference

4 August 2017

1 reference

PubMed ID

23777216