Plasticity of enzyme active sites (Q34768892)

4 August 2017

title

Plasticity of enzyme active sites (English)

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4 August 2017

3

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4 August 2017

2

Christine A Orengo

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4 August 2017

1

Annabel E Todd

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4 August 2017

publication date

1 August 2002

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4 August 2017

number of pages

8

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Trends in Biochemical Sciences

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published in

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4 August 2017

volume

27

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4 August 2017

issue

8

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4 August 2017

page(s)

419-426

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publication type of scholarly work

4 August 2017

review article

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The relation between the divergence of sequence and structure in proteins

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7 January 2021

Mechanistically diverse enzyme superfamilies: the importance of chemistry in the evolution of catalysis

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Evolution of function in protein superfamilies, from a structural perspective.

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On the origin of enzymatic species

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Understanding enzyme superfamilies. Chemistry As the fundamental determinant in the evolution of new catalytic activities

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Fold change in evolution of protein structures

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Evolution of an enzyme active site: The structure of a new crystal form of muconate lactonizing enzyme compared with mandelate racemase and enolase

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7 January 2021

A mixed disulfide bond in bacterial glutathione transferase: functional and evolutionary implications

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7 January 2021

Crystal structure of a theta-class glutathione transferase.

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7 January 2021

Structure-based redesign of the Catalytic/Metal binding site of Cfr 10I restriction endonuclease reveals importance of spatial rather than sequence conservation of active centre residues

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7 January 2021

The ferritins: molecular properties, iron storage function and cellular regulation

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Three-dimensional structure of the free radical protein of ribonucleotide reductase

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The dodecameric ferritin from Listeria innocua contains a novel intersubunit iron-binding site

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Redesigning the active site of Geotrichum candidum lipase

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The alpha/beta fold uracil DNA glycosylases: a common origin with diverse fates

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Directed evolution of a new catalytic site in 2-keto-3-deoxy-6-phosphogluconate aldolase from Escherichia coli

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7 January 2021

Role of a Buried Acid Group in the Mechanism of Action of Chymotrypsin

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7 January 2021

Structure of Subtilisin BPN′ at 2.5 Å Resolution

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7 January 2021

Analogous Enzymes: Independent Inventions in Enzyme Evolution

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The relationship between protein structure and function: a comprehensive survey with application to the yeast genome

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7 January 2021

The Zn-peptidase superfamily: functional convergence after evolutionary divergence

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7 January 2021

Convergent evolution of similar function in two structurally divergent enzymes

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7 January 2021

Déjá vu all over again

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7 January 2021

The structure of flavocytochrome c sulfide dehydrogenase from a purple phototrophic bacterium

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Staphylococcus aureus coenzyme A disulfide reductase, a new subfamily of pyridine nucleotide-disulfide oxidoreductase. Sequence, expression, and analysis of cdr.

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7 January 2021

Crystal structure of transaldolase B from Escherichia coli suggests a circular permutation of the alpha/beta barrel within the class I aldolase family

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7 January 2021

The evolution of alpha/beta barrel enzymes

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7 January 2021

Directed evolution of a (beta alpha)8-barrel enzyme to catalyze related reactions in two different metabolic pathways

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7 January 2021

Directed evolution of new catalytic activity using the alpha/beta-barrel scaffold

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7 January 2021

From structure to function: approaches and limitations

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7 January 2021

MOLSCRIPT: a program to produce both detailed and schematic plots of protein structures

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7 January 2021

Structure, catalytic mechanism, and evolution of the glutathione transferases

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7 January 2021

10.1016/S0968-0004(02)02158-8

Identifiers

DOI

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4 August 2017

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