Bile acid-mediated hepatocyte apoptosis and cholestatic liver disease (Q34753740)

4 August 2017

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title

Bile acid-mediated hepatocyte apoptosis and cholestatic liver disease (English)

1 reference

4 August 2017

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Guicciardi ME

1

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PubMed ID

12132783

4 August 2017

Gores GJ

series ordinal

2

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PubMed ID

12132783

4 August 2017

language of work or name

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1 June 2002

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Digestive and Liver Disease

4 August 2017

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4 August 2017

34

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4 August 2017

6

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4 August 2017

387-392

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A gene encoding a liver-specific ABC transporter is mutated in progressive familial intrahepatic cholestasis

4 August 2017

1 reference

https://api.crossref.org/works/10.1016%2FS1590-8658%2802%2980033-0

7 January 2021

BSEP: function and role in progressive familial intrahepatic cholestasis

1 reference

https://api.crossref.org/works/10.1016%2FS1590-8658%2802%2980033-0

7 January 2021

Identification of a nuclear receptor for bile acids

1 reference

https://api.crossref.org/works/10.1016%2FS1590-8658%2802%2980033-0

7 January 2021

Bile acids: natural ligands for an orphan nuclear receptor

1 reference

https://api.crossref.org/works/10.1016%2FS1590-8658%2802%2980033-0

7 January 2021

Endogenous bile acids are ligands for the nuclear receptor FXR/BAR

1 reference

https://api.crossref.org/works/10.1016%2FS1590-8658%2802%2980033-0

7 January 2021

Molecular basis for feedback regulation of bile acid synthesis by nuclear receptors

1 reference

https://api.crossref.org/works/10.1016%2FS1590-8658%2802%2980033-0

7 January 2021

Targeted disruption of the nuclear receptor FXR/BAR impairs bile acid and lipid homeostasis.

1 reference

https://api.crossref.org/works/10.1016%2FS1590-8658%2802%2980033-0

7 January 2021

Correction of liver disease by hepatocyte transplantation in a mouse model of progressive familial intrahepatic cholestasis.

1 reference

https://api.crossref.org/works/10.1016%2FS1590-8658%2802%2980033-0

7 January 2021

A novel role for ursodeoxycholic acid in inhibiting apoptosis by modulating mitochondrial membrane perturbation

1 reference

https://api.crossref.org/works/10.1016%2FS1590-8658%2802%2980033-0

7 January 2021

Influence of hydroxylation and conjugation of bile salts on their membrane-damaging properties--studies on isolated hepatocytes and lipid membrane vesicles

1 reference

https://api.crossref.org/works/10.1016%2FS1590-8658%2802%2980033-0

7 January 2021

In vitro effect of bile salts on rat liver plasma membrane, lipid fluidity, and ATPase activity

1 reference

https://api.crossref.org/works/10.1016%2FS1590-8658%2802%2980033-0

7 January 2021

Effects of bile salts on the plasma membranes of isolated rat hepatocytes

1 reference

https://api.crossref.org/works/10.1016%2FS1590-8658%2802%2980033-0

7 January 2021

Failure of hypoactive hypertrophic smooth endoplasmic reticulum to produce cholestasis in rats

1 reference

https://api.crossref.org/works/10.1016%2FS1590-8658%2802%2980033-0

7 January 2021

Hepatic injury induced by bile salts: correlation between biochemical and morphological events

1 reference

https://api.crossref.org/works/10.1016%2FS1590-8658%2802%2980033-0

7 January 2021

Effect of chenodeoxycholic and ursodeoxycholic acids on isolated adult human hepatocytes

1 reference

https://api.crossref.org/works/10.1016%2FS1590-8658%2802%2980033-0

7 January 2021

In vitro effect of free bile acids on the bile canaliular membrane phospholipids in the rat

1 reference

https://api.crossref.org/works/10.1016%2FS1590-8658%2802%2980033-0

7 January 2021

The order of hepatic cytotoxicity of bile salts in vitro does not agree with that examined in vivo in rats

1 reference

https://api.crossref.org/works/10.1016%2FS1590-8658%2802%2980033-0

7 January 2021

Hydrophilic and hydrophobic bile acids exhibit different cytotoxicities through cytolysis, interleukin-8 synthesis and apoptosis in the intestinal epithelial cell lines. IEC-6 and Caco-2 cells

1 reference

https://api.crossref.org/works/10.1016%2FS1590-8658%2802%2980033-0

7 January 2021

Comparative cytotoxic and cytoprotective effects of taurohyodeoxycholic acid (THDCA) and tauroursodeoxycholic acid (TUDCA) in HepG2 cell line

1 reference

https://api.crossref.org/works/10.1016%2FS1590-8658%2802%2980033-0

7 January 2021

Ursodeoxycholic acid may inhibit deoxycholic acid-induced apoptosis by modulating mitochondrial transmembrane potential and reactive oxygen species production

1 reference

https://api.crossref.org/works/10.1016%2FS1590-8658%2802%2980033-0

7 January 2021

Vitamin E reduces oxidant injury to mitochondria and the hepatotoxicity of taurochenodeoxycholic acid in the rat

1 reference

https://api.crossref.org/works/10.1016%2FS1590-8658%2802%2980033-0

7 January 2021

Bile acid-induced rat hepatocyte apoptosis is inhibited by antioxidants and blockers of the mitochondrial permeability transition

1 reference

https://api.crossref.org/works/10.1016%2FS1590-8658%2802%2980033-0

7 January 2021

Inhibition of bile-salt-induced hepatocyte apoptosis by the antioxidant lazaroid U83836E

1 reference

https://api.crossref.org/works/10.1016%2FS1590-8658%2802%2980033-0

7 January 2021

Ursodeoxycholic acid prevents cytochrome c release in apoptosis by inhibiting mitochondrial membrane depolarization and channel formation

1 reference

https://api.crossref.org/works/10.1016%2FS1590-8658%2802%2980033-0

7 January 2021

Role of oxidant stress in the permeability transition induced in rat hepatic mitochondria by hydrophobic bile acids

1 reference

https://api.crossref.org/works/10.1016%2FS1590-8658%2802%2980033-0

7 January 2021

Generation of hydroperoxides in isolated rat hepatocytes and hepatic mitochondria exposed to hydrophobic bile acids

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https://api.crossref.org/works/10.1016%2FS1590-8658%2802%2980033-0

7 January 2021

Increases of intracellular magnesium promote glycodeoxycholate-induced apoptosis in rat hepatocytes

1 reference

https://api.crossref.org/works/10.1016%2FS1590-8658%2802%2980033-0

7 January 2021

Hepatocyte apoptosis after bile duct ligation in the mouse involves Fas.

1 reference

https://api.crossref.org/works/10.1016%2FS1590-8658%2802%2980033-0

7 January 2021

Programmed cell death in animal development

1 reference

https://api.crossref.org/works/10.1016%2FS1590-8658%2802%2980033-0

7 January 2021

Caspases: the executioners of apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS1590-8658%2802%2980033-0

7 January 2021

Dysregulation of apoptosis as a mechanism of liver disease: an overview.

1 reference

https://api.crossref.org/works/10.1016%2FS1590-8658%2802%2980033-0

7 January 2021

Two CD95 (APO-1/Fas) signaling pathways

1 reference

https://api.crossref.org/works/10.1016%2FS1590-8658%2802%2980033-0

7 January 2021

Death receptors: signaling and modulation

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https://api.crossref.org/works/10.1016%2FS1590-8658%2802%2980033-0

7 January 2021

Mitochondria and apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS1590-8658%2802%2980033-0

7 January 2021

Cleavage of BID by caspase 8 mediates the mitochondrial damage in the Fas pathway of apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS1590-8658%2802%2980033-0

7 January 2021

Bid, a Bcl2 interacting protein, mediates cytochrome c release from mitochondria in response to activation of cell surface death receptors

1 reference

https://api.crossref.org/works/10.1016%2FS1590-8658%2802%2980033-0

7 January 2021

Bid induces the oligomerization and insertion of Bax into the outer mitochondrial membrane

1 reference

https://api.crossref.org/works/10.1016%2FS1590-8658%2802%2980033-0

7 January 2021

Toxic bile salts induce rodent hepatocyte apoptosis via direct activation of Fas.

1 reference

https://api.crossref.org/works/10.1016%2FS1590-8658%2802%2980033-0

7 January 2021

The bile acid-activated phosphatidylinositol 3-kinase pathway inhibits Fas apoptosis upstream of bid in rodent hepatocytes

1 reference

https://api.crossref.org/works/10.1016%2FS1590-8658%2802%2980033-0

7 January 2021

The Bcl-2 protein family: arbiters of cell survival

1 reference

https://api.crossref.org/works/10.1016%2FS1590-8658%2802%2980033-0

7 January 2021

Bax-induced cytochrome C release from mitochondria is independent of the permeability transition pore but highly dependent on Mg2+ ions

1 reference

https://api.crossref.org/works/10.1016%2FS1590-8658%2802%2980033-0

7 January 2021

Proapoptotic BAX and BAK: a requisite gateway to mitochondrial dysfunction and death

1 reference

https://api.crossref.org/works/10.1016%2FS1590-8658%2802%2980033-0

7 January 2021

Effect of oxypurinol, a xanthine oxidase inhibitor, on hepatic injury in the bile duct-ligated rat

1 reference

https://api.crossref.org/works/10.1016%2FS1590-8658%2802%2980033-0

7 January 2021

The effect of idebenone, a coenzyme Q analogue, on hydrophobic bile acid toxicity to isolated rat hepatocytes and hepatic mitochondria

1 reference

https://api.crossref.org/works/10.1016%2FS1590-8658%2802%2980033-0

7 January 2021

The bile acid glycochenodeoxycholate induces trail-receptor 2/DR5 expression and apoptosis.

1 reference

https://api.crossref.org/works/10.1016%2FS1590-8658%2802%2980033-0

7 January 2021

Ursodeoxycholic acid cytoprotection: dancing with death receptors and survival pathways

1 reference

https://api.crossref.org/works/10.1016%2FS1590-8658%2802%2980033-0

7 January 2021

The bile acid taurochenodeoxycholate activates a phosphatidylinositol 3-kinase-dependent survival signaling cascade

1 reference

https://api.crossref.org/works/10.1016%2FS1590-8658%2802%2980033-0

7 January 2021

Differential modulation of cellular death and survival pathways by conjugated bile acids

1 reference

https://api.crossref.org/works/10.1016%2FS1590-8658%2802%2980033-0

7 January 2021

Inhibition of the MAPK and PI3K pathways enhances UDCA-induced apoptosis in primary rodent hepatocytes

1 reference

https://api.crossref.org/works/10.1016%2FS1590-8658%2802%2980033-0

7 January 2021

Mitogen-activated protein kinases mediate the stimulation of bile acid secretion by tauroursodeoxycholate in rat liver

1 reference

https://api.crossref.org/works/10.1016%2FS1590-8658%2802%2980033-0

7 January 2021

Activation and role of mitogen-activated protein kinases in deoxycholic acid-induced apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS1590-8658%2802%2980033-0

7 January 2021

Deoxycholic acid (DCA) causes ligand-independent activation of epidermal growth factor receptor (EGFR) and FAS receptor in primary hepatocytes: inhibition of EGFR/mitogen-activated protein kinase-signaling module enhances DCA-induced apoptosis.

1 reference

https://api.crossref.org/works/10.1016%2FS1590-8658%2802%2980033-0

7 January 2021

Bile acids induce cyclooxygenase-2 expression via the epidermal growth factor receptor in a human cholangiocarcinoma cell line

1 reference

https://api.crossref.org/works/10.1016%2FS1590-8658%2802%2980033-0

7 January 2021

Activation of the Raf-1/MEK/ERK cascade by bile acids occurs via the epidermal growth factor receptor in primary rat hepatocytes

1 reference

https://api.crossref.org/works/10.1016%2FS1590-8658%2802%2980033-0

7 January 2021

10.1016/S1590-8658(02)80033-0

Identifiers

DOI

1 reference

4 August 2017

1 reference

PubMed ID

12132783