Anxiety is associated with reduced central serotonin transporter availability in unmedicated patients with unipolar major depression: a [11C]DASB PET study. (Q34749301)

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English	Anxiety is associated with reduced central serotonin transporter availability in unmedicated patients with unipolar major depression: a [11C]DASB PET study.	scientific article

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2 January 2020

Anxiety is associated with reduced central serotonin transporter availability in unmedicated patients with unipolar major depression: a [11C]DASB PET study (English)

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solute carrier family 6 member 4

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Michael N Smolka

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M Reimold

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A Knobel

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A Zimmer

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K Mann

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C Solbach

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G Reischl

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F Schwärzler

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G Gründer

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H-J Machulla

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R Bares

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A Heinz

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12 February 2008

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Molecular Psychiatry

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606-13, 557

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2 January 2020

describes a project that uses

positron emission tomography

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Temperament and Character Inventory

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Fluoxetine, but not tricyclic antidepressants, potentiates the 5-hydroxytryptophan-mediated increase in plasma cortisol and prolactin secretion in subjects with major depression or with obsessive compulsive disorder.

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21 January 2018

Serotonin transporter occupancy of five selective serotonin reuptake inhibitors at different doses: an [11C]DASB positron emission tomography study.

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21 January 2018

"Serotonin Depression"—A Biochemical Subgroup Within the Affective Disorders?

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21 January 2018

Reduced brain serotonin transporter availability in major depression as measured by [123I]-2 beta-carbomethoxy-3 beta-(4-iodophenyl)tropane and single photon emission computed tomography.

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21 January 2018

Sex differences in diencephalon serotonin transporter availability in major depression

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21 January 2018

[123I]-beta-CIT SPECT imaging shows reduced brain serotonin transporter availability in drug-free depressed patients with seasonal affective disorder.

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21 January 2018

SPECT imaging of dopamine and serotonin transporters with [123I]beta-CIT: pharmacological characterization of brain uptake in nonhuman primates.

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21 January 2018

In vivo association between alcohol intoxication, aggression, and serotonin transporter availability in nonhuman primates.

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Relationship between cortisol and serotonin metabolites and transporters in alcoholism [correction of alcolholism].

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PET examination of the monoamine transporter with [11C]beta-CIT and [11C]beta-CFT in early Parkinson's disease.

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21 January 2018

Inhibition of serotonin transport by (+)McN5652 is noncompetitive.

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21 January 2018

Lower serotonin transporter binding potential in the human brain during major depressive episodes

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21 January 2018

Serotonin transporter binding in patients with mood disorders: a PET study with [11C](+)McN5652.

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Imaging the serotonin transporter with positron emission tomography: initial human studies with [11C]DAPP and [11C]DASB.

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21 January 2018

DASB -in vitro binding characteristics on human recombinant monoamine transporters with regard to its potential as positron emission tomography (PET) tracer

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21 January 2018

Brain serotonin transporter binding potential measured with carbon 11-labeled DASB positron emission tomography: effects of major depressive episodes and severity of dysfunctional attitudes.

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21 January 2018

Sex differences in [123I]beta-CIT SPECT measures of dopamine and serotonin transporter availability in healthy smokers and nonsmokers.

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21 January 2018

Association of anxiety-related traits with a polymorphism in the serotonin transporter gene regulatory region

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21 January 2018

A relationship between serotonin transporter genotype and in vivo protein expression and alcohol neurotoxicity.

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21 January 2018

Central serotonin transporter availability measured with [123I]beta-CIT SPECT in relation to serotonin transporter genotype

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21 January 2018

Midbrain serotonin transporter binding potential measured with [11C]DASB is affected by serotonin transporter genotype

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21 January 2018

Novel 5-HTTLPR allele associates with higher serotonin transporter binding in putamen: a [(11)C] DASB positron emission tomography study.

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An Inventory for Measuring Depression

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Linearized reference tissue parametric imaging methods: application to [11C]DASB positron emission tomography studies of the serotonin transporter in human brain

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Acute occupancy of brain serotonin transporter by sertraline as measured by [11C]DASB and positron emission tomography

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Effect of spatial smoothing on t-maps: arguments for going back from t-maps to masked contrast images.

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Occupancy of serotonin transporters by paroxetine and citalopram during treatment of depression: a [(11)C]DASB PET imaging study

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The effect of paroxetine on 5-HT(2A) receptors in depression: an [(18)F]setoperone PET imaging study

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Serotonin transporter genetic variation and the response of the human amygdala

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A susceptibility gene for affective disorders and the response of the human amygdala

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Amygdala-prefrontal coupling depends on a genetic variation of the serotonin transporter

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5-HTTLPR polymorphism impacts human cingulate-amygdala interactions: a genetic susceptibility mechanism for depression

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Discovering endophenotypes for major depression

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Selective alteration of personality and social behavior by serotonergic intervention

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Tryptophan depletion in SSRI-recovered depressed outpatients

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?-CIT SPECT demonstrates blockade of 5HT-uptake sites by citalopram in the human brain in vivo

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CSF monoamine metabolites in melancholia

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based on heuristic

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Neurotransmitter actions in the thalamus and cerebral cortex

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Serotonin clearance in vivo is altered to a greater extent by antidepressant-induced downregulation of the serotonin transporter than by acute blockade of this transporter.

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based on heuristic

inferred from DOI database lookup

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