GSK-3 modulates cellular responses to a broad spectrum of kinase inhibitors (Q34735363)

4 August 2017

GSK-3 modulates cellular responses to a broad spectrum of kinase inhibitors (English)

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4 August 2017

Curtis A Thorne

1

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4 August 2017

Chonlarat Wichaidit

2

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4 August 2017

Adam D Coster

3

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4 August 2017

Bruce A Posner

4

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4 August 2017

Lani F Wu

5

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4 August 2017

Steven J Altschuler

6

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4 August 2017

17 November 2014

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4 August 2017

Nature Chemical Biology

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4 August 2017

11

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4 August 2017

1

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4 August 2017

58-63

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https://scigraph.springernature.com/pub.10.1038/nchembio.1690

4 August 2017

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7 July 2018

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What Are the bona fide GSK3 Substrates?

7 July 2018

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7 July 2018

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Small-molecule inhibition of Wnt signaling through activation of casein kinase 1α

7 July 2018

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Immortalized epithelial cells derived from human colon biopsies express stem cell markers and differentiate in vitro

7 July 2018

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mTOR and cancer: many loops in one pathway.

7 July 2018

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Direct small-molecule kinase activation: Novel approaches for a new era of drug discovery

7 July 2018

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Polo-like kinase (PLK) inhibitors in preclinical and early clinical development in oncology

7 July 2018

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BI 6727, a Polo-like kinase inhibitor with improved pharmacokinetic profile and broad antitumor activity

7 July 2018

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Active-site inhibitors of mTOR target rapamycin-resistant outputs of mTORC1 and mTORC2

7 July 2018

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An ATP-competitive mammalian target of rapamycin inhibitor reveals rapamycin-resistant functions of mTORC1

7 July 2018

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A complex interplay between Akt, TSC2 and the two mTOR complexes

7 July 2018

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Polo on the Rise-from Mitotic Entry to Cytokinesis with Plk1.

7 July 2018

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GSK-3 beta targets Cdc25A for ubiquitin-mediated proteolysis, and GSK-3 beta inactivation correlates with Cdc25A overproduction in human cancers.

7 July 2018

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GSK-3 inhibitors induce chromosome instability

7 July 2018

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Functional redundancy of GSK-3alpha and GSK-3beta in Wnt/beta-catenin signaling shown by using an allelic series of embryonic stem cell lines

7 July 2018

1 reference

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S6K1 regulates GSK3 under conditions of mTOR-dependent feedback inhibition of Akt.

7 July 2018

1 reference

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mTOR and cancer: insights into a complex relationship

7 July 2018

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mTOR inhibition induces upstream receptor tyrosine kinase signaling and activates Akt

7 July 2018

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Mammalian TOR complex 2 controls the actin cytoskeleton and is rapamycin insensitive

7 July 2018

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Dual regulation of Snail by GSK-3beta-mediated phosphorylation in control of epithelial-mesenchymal transition

7 July 2018

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Rictor, a novel binding partner of mTOR, defines a rapamycin-insensitive and raptor-independent pathway that regulates the cytoskeleton

7 July 2018

1 reference

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GSK-3: tricks of the trade for a multi-tasking kinase

7 July 2018

1 reference

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Regulation of Wnt signaling during adipogenesis

7 July 2018

1 reference

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Control of beta-catenin phosphorylation/degradation by a dual-kinase mechanism

7 July 2018

1 reference

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A common phosphate binding site explains the unique substrate specificity of GSK3 and its inactivation by phosphorylation

7 July 2018

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GSK3, a master switch regulating cell-fate specification and tumorigenesis

7 July 2018

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A GSK3-binding peptide from FRAT1 selectively inhibits the GSK3-catalysed phosphorylation of axin and beta-catenin

7 July 2018

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The axis-inducing activity, stability, and subcellular distribution of beta-catenin is regulated in Xenopus embryos by glycogen synthase kinase 3

7 July 2018

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Role of glycogen synthase kinase-3 in the phosphatidylinositol 3-Kinase/Akt cell survival pathway.

7 July 2018

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Kinase-inactive glycogen synthase kinase 3beta promotes Wnt signaling and mammary tumorigenesis.

21 January 2018

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Expression, localization, and activity of glycogen synthase kinase 3beta during mouse skin tumorigenesis.

21 January 2018

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Rapamycin inhibits mTORC1, but not completely.

21 January 2018

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ER stress inhibits mTORC2 and Akt signaling through GSK-3β-mediated phosphorylation of rictor.

21 January 2018

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https://api.crossref.org/works/10.1038%2FNCHEMBIO.1690

Phosphorylated GSK3beta-ser9 and EGFR are good prognostic factors for lung carcinomas.

21 January 2018

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Phosphoserine as a recognition determinant for glycogen synthase kinase-3: phosphorylation of a synthetic peptide based on the G-component of protein phosphatase-1

26 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25402767

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/NCHEMBIO.1690

1 reference

Dimensions Publication ID

4 August 2017

0 references

1 reference

4 August 2017

1 reference