Endothelial activation: intracellular signaling pathways (Q34731148)

4 August 2017

2 references

11 October 2019

26 August 2020

Endothelial activation: intracellular signaling pathways (English)

1 reference

4 August 2017

0 references

1 reference

11 October 2019

1 reference

26 August 2020

Jordan S Pober

1

1 reference

4 August 2017

9 May 2002

3 references

Arthritis Research and Therapy

4 August 2017

11 October 2019

26 August 2020

1 reference

4 August 2017

2 references

11 October 2019

26 August 2020

4 Suppl 3

1 reference

4 August 2017

S109-16

1 reference

https://scigraph.springernature.com/pub.10.1186/ar576

4 August 2017

0 references

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7 July 2018

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Caveolin-1 associates with TRAF2 to form a complex that is recruited to tumor necrosis factor receptors

7 July 2018

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The death domain of tumor necrosis factor receptor 1 is necessary but not sufficient for Golgi retention of the receptor and mediates receptor desensitization

7 July 2018

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TNFRSF1A mutations and autoinflammatory syndromes

7 July 2018

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A novel mechanism of TRAF signaling revealed by structural and functional analyses of the TRADD-TRAF2 interaction

7 July 2018

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MEK kinase 1 is critically required for c-Jun N-terminal kinase activation by proinflammatory stimuli and growth factor-induced cell migration.

7 July 2018

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Severe liver degeneration and lack of NF-kappaB activation in NEMO/IKKgamma-deficient mice

7 July 2018

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A phosphatidylinositol 3-kinase/Akt pathway, activated by tumor necrosis factor or interleukin-1, inhibits apoptosis but does not activate NFkappaB in human endothelial cells

7 July 2018

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A functional role of I kappa B-epsilon in endothelial cell activation

7 July 2018

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Of man and mouse: leukocyte and endothelial adhesion molecule deficiencies.

7 July 2018

1 reference

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Phosphorylation of tumor necrosis factor receptor CD120a (p55) by p42(mapk/erk2) induces changes in its subcellular localization

7 July 2018

1 reference

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RING fingers mediate ubiquitin-conjugating enzyme (E2)-dependent ubiquitination

7 July 2018

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Recent advances in the molecular basis of TNF signal transduction.

7 July 2018

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The beginning of the end: IkappaB kinase (IKK) and NF-kappaB activation

7 July 2018

1 reference

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NF-kappaB activation by tumour necrosis factor requires the Akt serine-threonine kinase

7 July 2018

1 reference

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The IKKbeta subunit of IkappaB kinase (IKK) is essential for nuclear factor kappaB activation and prevention of apoptosis

7 July 2018

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Embryonic lethality, liver degeneration, and impaired NF-kappa B activation in IKK-beta-deficient mice

7 July 2018

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Inhibition of receptor internalization by monodansylcadaverine selectively blocks p55 tumor necrosis factor receptor death domain signaling

7 July 2018

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TNF recruits TRADD to the plasma membrane but not the trans-Golgi network, the principal subcellular location of TNF-R1

7 July 2018

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Prevention of constitutive TNF receptor 1 signaling by silencer of death domains

7 July 2018

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Tumor necrosis factor- induces adhesion molecule expression through the sphingosine kinase pathway

7 July 2018

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Regulation of ceramide production and apoptosis

7 July 2018

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The death domain kinase RIP mediates the TNF-induced NF-kappaB signal

7 July 2018

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Role of activating protein-1 in the regulation of the vascular cell adhesion molecule-1 gene expression by tumor necrosis factor-alpha

7 July 2018

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Early lethality, functional NF-kappaB activation, and increased sensitivity to TNF-induced cell death in TRAF2-deficient mice

7 July 2018

1 reference

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CD30-dependent degradation of TRAF2: implications for negative regulation of TRAF signaling and the control of cell survival

7 July 2018

1 reference

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CREB-binding protein/p300 are transcriptional coactivators of p65

7 July 2018

1 reference

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Transgenic and knockout analyses of the role of TNF in immune regulation and disease pathogenesis.

7 July 2018

1 reference

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The NF-kappa B and I kappa B proteins: new discoveries and insights

7 July 2018

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Activation and homologous desensitization of human endothelial cells by CD40 ligand, tumor necrosis factor, and interleukin 1.

7 July 2018

1 reference

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A sustained reduction in IkappaB-beta may contribute to persistent NF-kappaB activation in human endothelial cells

7 July 2018

1 reference

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TNF-dependent recruitment of the protein kinase RIP to the TNF receptor-1 signaling complex

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3240152

TRADD-TRAF2 and TRADD-FADD interactions define two distinct TNF receptor 1 signal transduction pathways

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3240152

Chondrodysplasia and neurological abnormalities in ATF-2-deficient mice

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3240152

Ligand passing: the 75-kDa tumor necrosis factor (TNF) receptor recruits TNF for signaling by the 55-kDa TNF receptor.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3240152

A set of inducible genes expressed by activated human monocytic and endothelial cells contain kappa B-like sites that specifically bind c-Rel-p65 heterodimers.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3240152

Disparate localization of 55-kd and 75-kd tumor necrosis factor receptors in human endothelial cells.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3240152

The TNF receptor 1-associated protein TRADD signals cell death and NF-kappa B activation

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3240152

Differential regulation of vascular cell adhesion molecule 1 gene expression by specific NF-kappa B subunits in endothelial and epithelial cells

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3240152

Transcriptional regulation of endothelial cell adhesion molecules: NF-kappa B and cytokine-inducible enhancers.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3240152

Cell type-specific transactivation of the VCAM-1 promoter through an NF-kappa B enhancer motif

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3240152

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3240152

Inducibility and expression of microvascular endothelial adhesion molecules in lesional, perilesional, and uninvolved skin of psoriatic patients

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3240152

Three NF-kappa B binding sites in the human E-selectin gene required for maximal tumor necrosis factor alpha-induced expression

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3240152

Traffic signals for lymphocyte recirculation and leukocyte emigration: the multistep paradigm

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3240152

Tumor necrosis factor activates human endothelial cells through the p55 tumor necrosis factor receptor but the p75 receptor contributes to activation at low tumor necrosis factor concentration

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3240152

Neutrophil-endothelial cell interactions. Modulation of neutrophil adhesiveness induced by complement fragments C5a and C5a des arg and formyl-methionyl-leucyl-phenylalanine in vitro

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3240152

Interleukin 1 acts on cultured human vascular endothelium to increase the adhesion of polymorphonuclear leukocytes, monocytes, and related leukocyte cell lines

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3240152

Structural characteristics of the 5' region of the human ICAM-1 gene

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3240152

Leukocyte-endothelial cell recognition: Three (or more) steps to specificity and diversity

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3240152

Tumor necrosis factor combines with IL-4 or IFN-gamma to selectively enhance endothelial cell adhesiveness for T cells. The contribution of vascular cell adhesion molecule-1-dependent and -independent binding mechanisms

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3240152

Cytokines and endothelial cell biology

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3240152

Soluble and cell surface receptors for tumor necrosis factor.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3240152

Effects of tumor necrosis factor, lipopolysaccharide, and IL-4 on the expression of vascular cell adhesion molecule-1 in vivo. Correlation with CD3+ T cell infiltration

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3240152

A role for c-Raf kinase and Ha-Ras in cytokine-mediated induction of cell adhesion molecules.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3240152

Cooperativity between two NF-kappa B complexes, mediated by high-mobility-group protein I(Y), is essential for cytokine-induced expression of the E-selectin promoter

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3240152

Structure of the murine VCAM1 gene.

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3240152

Ceramide is not a signal for tumor necrosis factor-induced gene expression but does cause programmed cell death in human vascular endothelial cells

26 October 2018

1 reference

12 December 2020

P- and E-selectin mediate recruitment of T-helper-1 but not T-helper-2 cells into inflamed tissues

1 reference

12 December 2020

TNF initiates E-selectin transcription in human endothelial cells through parallel TRAF-NF-kappa B and TRAF-RAC/CDC42-JNK-c-Jun/ATF2 pathways

1 reference

12 December 2020

The distinct roles of TRAF2 and RIP in IKK activation by TNF-R1: TRAF2 recruits IKK to TNF-R1 while RIP mediates IKK activation

1 reference

12 December 2020

Tumor necrosis factor is delivered to mitochondria where a tumor necrosis factor-binding protein is localized

1 reference

12 December 2020

Apoptosis-inducing agents cause rapid shedding of tumor necrosis factor receptor 1 (TNFR1). A nonpharmacological explanation for inhibition of TNF-mediated activation

1 reference

12 December 2020

IFN-gamma enhances endothelial activation induced by tumor necrosis factor but not IL-1

1 reference

12 December 2020

Mutational analysis and NMR studies of the death domain of the tumor necrosis factor receptor-1

1 reference

12 December 2020

Expression of tumor necrosis factor receptors in normal kidney and rejecting renal transplants

1 reference

12 December 2020

Microvascular effects of anaphylatoxins C3a and C5a

1 reference

12 December 2020

Four different classes of inhibitors of receptor-mediated endocytosis decrease tumor necrosis factor-induced gene expression in human endothelial cells

1 reference

12 December 2020

Heterogeneity of dermal microvascular endothelial cell antigen expression and cytokine responsiveness in situ and in cell culture

1 reference

12 December 2020

cAMP and tumor necrosis factor competitively regulate transcriptional activation through and nuclear factor binding to the cAMP-responsive element/activating transcription factor element of the endothelial leukocyte adhesion molecule-1 (E-selectin)

1 reference

12 December 2020

Identifiers

DOI

10.1186/AR576

1 reference

PubMed ID

12110129

Dimensions Publication ID

4 August 2017

0 references

1 reference

4 August 2017

1 reference

PubMed ID

12110129