Repression of let-7 by transforming growth factor-β1-induced Lin28 upregulates collagen expression in glomerular mesangial cells under diabetic conditions (Q34726882)

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English	Repression of let-7 by transforming growth factor-β1-induced Lin28 upregulates collagen expression in glomerular mesangial cells under diabetic conditions	scientific article

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scholarly article

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4 August 2017

Repression of let-7 by transforming growth factor-β1-induced Lin28 upregulates collagen expression in glomerular mesangial cells under diabetic conditions (English)

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4 August 2017

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Rama Natarajan

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Mitsuo Kato

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Linda Lanting

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Nancy Castro

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Bo Young Nam

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Mei Wang

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29 October 2014

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American Journal of Physiology - Renal Physiology

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F1390-403

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describes a project that uses

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Transforming growth factor β1 (TGF-β1) enhances expression of profibrotic genes through a novel signaling cascade and microRNAs in renal mesangial cells

1 reference

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7 July 2018

Diabetic nephropathy--emerging epigenetic mechanisms

1 reference

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7 July 2018

Lin28 induces epithelial-to-mesenchymal transition and stemness via downregulation of let-7a in breast cancer cells

1 reference

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Lin28B is an oncofetal circulating cancer stem cell-like marker associated with recurrence of hepatocellular carcinoma.

1 reference

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7 July 2018

Diabetic nephropathy: diagnosis and treatment

1 reference

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7 July 2018

Transforming growth factor-β1-mediated renal fibrosis is dependent on the regulation of transforming growth factor receptor 1 expression by let-7b.

1 reference

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7 July 2018

FOG2 protein down-regulation by transforming growth factor-β1-induced microRNA-200b/c leads to Akt kinase activation and glomerular mesangial hypertrophy related to diabetic nephropathy.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4269695

7 July 2018

TGF-β induces acetylation of chromatin and of Ets-1 to alleviate repression of miR-192 in diabetic nephropathy

1 reference

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7 July 2018

Lipoxins attenuate renal fibrosis by inducing let-7c and suppressing TGFβR1.

1 reference

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7 July 2018

LIN28/LIN28B: an emerging oncogenic driver in cancer stem cells

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7 July 2018

Blockade of miR-150 maturation by MLL-fusion/MYC/LIN-28 is required for MLL-associated leukemia

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7 July 2018

TGF-β/Smad signaling in kidney disease.

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7 July 2018

How does TGF-β mediate tubulointerstitial fibrosis?

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7 July 2018

Lin28 regulates HER2 and promotes malignancy through multiple mechanisms

1 reference

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7 July 2018

A mirror of two faces: Lin28 as a master regulator of both miRNA and mRNA.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4269695

7 July 2018

High expression of Lin28 is associated with tumour aggressiveness and poor prognosis of patients in oesophagus cancer

1 reference

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7 July 2018

MicroRNAs and the glomerulus

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4269695

7 July 2018

Let-7d functions as novel regulator of epithelial-mesenchymal transition and chemoresistant property in oral cancer

1 reference

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7 July 2018

Diabetes complications: the microRNA perspective.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4269695

7 July 2018

MicroRNA-21 orchestrates high glucose-induced signals to TOR complex 1, resulting in renal cell pathology in diabetes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4269695

7 July 2018

A microRNA circuit mediates transforming growth factor-β1 autoregulation in renal glomerular mesangial cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4269695

7 July 2018

MicroRNA-29c is a signature microRNA under high glucose conditions that targets Sprouty homolog 1, and its in vivo knockdown prevents progression of diabetic nephropathy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4269695

7 July 2018

A glimpse of various pathogenetic mechanisms of diabetic nephropathy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4269695

7 July 2018

Collagen regulation of let-7 in pancreatic cancer involves TGF-β1-mediated membrane type 1-matrix metalloproteinase expression

1 reference

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7 July 2018

miR-192 mediates TGF-beta/Smad3-driven renal fibrosis

1 reference

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Inhibition and role of let-7d in idiopathic pulmonary fibrosis

1 reference

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Abnormalities in signaling pathways in diabetic nephropathy.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4269695

7 July 2018

MicroRNA control of signal transduction

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4269695

7 July 2018

Pluripotency factors Lin28 and Oct4 identify a sub-population of stem cell-like cells in ovarian cancer

1 reference

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7 July 2018

TGF-beta activates Akt kinase through a microRNA-dependent amplifying circuit targeting PTEN

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4269695

7 July 2018

Lin28 promotes transformation and is associated with advanced human malignancies

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4269695

7 July 2018

Lin28 mediates the terminal uridylation of let-7 precursor MicroRNA

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4269695

7 July 2018

Lin-28 interaction with the Let-7 precursor loop mediates regulated microRNA processing

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4269695

7 July 2018

Effects of cholesterol-tagged small interfering RNAs targeting 12/15-lipoxygenase on parameters of diabetic nephropathy in a mouse model of type 1 diabetes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4269695

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TGF-beta in renal injury and disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4269695

7 July 2018

MicroRNA-192 in diabetic kidney glomeruli and its function in TGF-beta-induced collagen expression via inhibition of E-box repressors.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4269695

7 July 2018

Mesangial cell hypertrophy by high glucose is mediated by downregulation of the tumor suppressor PTEN

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4269695

7 July 2018

Role of upstream stimulatory factors in regulation of renal transforming growth factor-beta1.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4269695

7 July 2018

Kidney disease as a risk factor for development of cardiovascular disease: a statement from the American Heart Association Councils on Kidney in Cardiovascular Disease, High Blood Pressure Research, Clinical Cardiology, and Epidemiology and Preventi

1 reference

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Role of Smad4 on TGF-beta-induced extracellular matrix stimulation in mesangial cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4269695

7 July 2018

Smads: transcriptional activators of TGF-beta responses

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4269695

7 July 2018

The extracellular matrix in diabetic nephropathy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4269695

7 July 2018

Expression of transforming growth factor beta is elevated in human and experimental diabetic nephropathy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4269695

7 July 2018

Hyperglycemia and diabetic kidney disease. The case for transforming growth factor-beta as a key mediator

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4269695

7 July 2018

Lin28: A microRNA regulator with a macro role

1 reference

https://pubmed.ncbi.nlm.nih.gov/25354942

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

It's a Smad world: regulation of TGF-beta signaling in the kidney

1 reference

https://pubmed.ncbi.nlm.nih.gov/25354942

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Renal hypertrophy is associated with upregulation of TGF-beta 1 gene expression in diabetic BB rat and NOD mouse

1 reference

https://pubmed.ncbi.nlm.nih.gov/25354942

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The downregulation of microRNA let-7a contributes to the excessive expression of type I collagen in systemic and localized scleroderma

1 reference

https://pubmed.ncbi.nlm.nih.gov/25354942

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1152/AJPRENAL.00458.2014

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7 June 2020

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7 June 2020

1 reference

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7 June 2020

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