Spartan deficiency causes genomic instability and progeroid phenotypes (Q34722436)

4 August 2017

Spartan deficiency causes genomic instability and progeroid phenotypes (English)

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4 August 2017

8

Jan M van Deursen

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4 August 2017

3

Darren J Baker

1 reference

4 August 2017

Reeja S Maskey

1

1 reference

4 August 2017

Myoung Shin Kim

2

1 reference

4 August 2017

Bennett Childs

4

1 reference

4 August 2017

Liviu A Malureanu

5

1 reference

4 August 2017

Karthik B Jeganathan

6

1 reference

4 August 2017

Yuka Machida

7

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4 August 2017

Yuichi J Machida

9

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4 August 2017

language of work or name

English

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publication date

11 December 2014

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4 August 2017

Nature Communications

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4 August 2017

5

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4 August 2017

5744

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Creative Commons Attribution 4.0 International

4 August 2017

start time

1 December 2014

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April 2022 Public Data File from Crossref

copyright status

copyrighted

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describes a project that uses

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC4269170/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

exact match

https://scigraph.springernature.com/pub.10.1038/ncomms6744

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cites work

Mutations in SPRTN cause early onset hepatocellular carcinoma, genomic instability and progeroid features

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Replication stress is a potent driver of functional decline in ageing haematopoietic stem cells

7 July 2018

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Causes and consequences of replication stress

7 July 2018

1 reference

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7 July 2018

The hallmarks of aging

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DNA synthesis by Pol η promotes fragile site stability by preventing under-replicated DNA in mitosis

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4269170

Genome instability and aging

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4269170

Regulation of error-prone translesion synthesis by Spartan/C1orf124.

7 July 2018

1 reference

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Mechanism of replicative DNA polymerase delta pausing and a potential role for DNA polymerase kappa in common fragile site replication

7 July 2018

1 reference

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DVC1 (C1orf124) recruits the p97 protein segregase to sites of DNA damage

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4269170

DVC1 (C1orf124) is a DNA damage-targeting p97 adaptor that promotes ubiquitin-dependent responses to replication blocks

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4269170

Characterization of human Spartan/C1orf124, an ubiquitin-PCNA interacting regulator of DNA damage tolerance

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4269170

Proliferating cell nuclear antigen (PCNA)-binding protein C1orf124 is a regulator of translesion synthesis

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4269170

Spartan/C1orf124 is important to prevent UV-induced mutagenesis

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4269170

Spartan/C1orf124, a reader of PCNA ubiquitylation and a regulator of UV-induced DNA damage response

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4269170

Y-family DNA polymerases and their role in tolerance of cellular DNA damage.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4269170

DNA polymerase zeta is required for proliferation of normal mammalian cells

7 July 2018

1 reference

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ROCK inhibitor and feeder cells induce the conditional reprogramming of epithelial cells

7 July 2018

1 reference

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Clearance of p16Ink4a-positive senescent cells delays ageing-associated disorders

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4269170

PCNA ubiquitination is important, but not essential for translesion DNA synthesis in mammalian cells.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4269170

Replication stress induces 53BP1-containing OPT domains in G1 cells

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4269170

53BP1 nuclear bodies form around DNA lesions generated by mitotic transmission of chromosomes under replication stress

7 July 2018

1 reference

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Molecular mechanisms of micronucleus, nucleoplasmic bridge and nuclear bud formation in mammalian and human cells

7 July 2018

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Genomic instability--an evolving hallmark of cancer

7 July 2018

1 reference

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A mouse model of ATR-Seckel shows embryonic replicative stress and accelerated aging

7 July 2018

1 reference

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Human DNA polymerase eta is required for common fragile site stability during unperturbed DNA replication

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4269170

DNA damage tolerance: when it's OK to make mistakes

7 July 2018

1 reference

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Role of TLS DNA polymerases eta and kappa in processing naturally occurring structured DNA in human cells

7 July 2018

1 reference

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DNA damage and ageing: new-age ideas for an age-old problem

7 July 2018

1 reference

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Opposing roles for p16Ink4a and p19Arf in senescence and ageing caused by BubR1 insufficiency

7 July 2018

1 reference

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Deletion of the developmentally essential gene ATR in adult mice leads to age-related phenotypes and stem cell loss

7 July 2018

1 reference

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Restoration of p53 function leads to tumour regression in vivo

7 July 2018

1 reference

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Early aging-associated phenotypes in Bub3/Rae1 haploinsufficient mice

7 July 2018

1 reference

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Culture of mouse prostatic epithelial cells from genetically engineered mice

7 July 2018

1 reference

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Interaction of human DNA polymerase eta with monoubiquitinated PCNA: a possible mechanism for the polymerase switch in response to DNA damage

7 July 2018

1 reference

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Aging and genome maintenance: lessons from the mouse?

7 July 2018

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Involvement of mouse Rev3 in tolerance of endogenous and exogenous DNA damage

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4269170

Enumeration of the simian virus 40 early region elements necessary for human cell transformation

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4269170

DNA double-stranded breaks induce histone H2AX phosphorylation on serine 139

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4269170

Mitosis-specific phosphorylation of histone H3 initiates primarily within pericentromeric heterochromatin during G2 and spreads in an ordered fashion coincident with mitotic chromosome condensation

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4269170

G2 arrest and impaired nucleocytoplasmic transport in mouse embryos lacking the proto-oncogene CAN/Nup214

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4269170

Histone H3 phosphorylation and expression of cyclins A and B1 measured in individual cells during their progression through G2 and mitosis.

7 July 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS6744

Gene targeting methods for studying nuclear transport factors in mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS6744

BubR1 insufficiency causes early onset of aging-associated phenotypes and infertility in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS6744

Disruption of mouse polymerase zeta (Rev3) leads to embryonic lethality and impairs blastocyst development in vitro.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS6744

Disruption of the Rev3l-encoded catalytic subunit of polymerase zeta in mice results in early embryonic lethality.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS6744

Disruption of the developmentally regulated Rev3l gene causes embryonic lethality.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS6744

Sez4 gene encoding an elongation subunit of DNA polymerase zeta is required for normal embryogenesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCOMMS6744

21 January 2018

Identifiers

DOI

10.1038/NCOMMS6744

1 reference

Dimensions Publication ID

4 August 2017

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4 August 2017

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