Lower oxidative DNA damage despite greater ROS production in muscles from rats selectively bred for high running capacity (Q34720083)

4 August 2017

Lower oxidative DNA damage despite greater ROS production in muscles from rats selectively bred for high running capacity (English)

1 reference

4 August 2017

0 references

4

1 reference

4 August 2017

5

1 reference

4 August 2017

6

Mark A Tarnopolsky

1 reference

4 August 2017

Constance Tweedie

1

1 reference

4 August 2017

Caroline Romestaing

2

1 reference

4 August 2017

Yan Burelle

3

1 reference

4 August 2017

Scott Seadon

7

1 reference

4 August 2017

Steven L Britton

8

1 reference

4 August 2017

Lauren G Koch

9

1 reference

4 August 2017

Russell T Hepple

10

1 reference

4 August 2017

language of work or name

1 reference

9 December 2010

1 reference

American Journal of Physiology - Regulatory, Integrative and Comparative Physiology

4 August 2017

1 reference

4 August 2017

300

1 reference

4 August 2017

R544-53

1 reference

4 August 2017

3

1 reference

describes a project that uses

4 August 2017

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3064275/fullTextXML

inferred from PubMed Central ID database lookup

cites work

Hydrogen peroxide efflux from muscle mitochondria underestimates matrix superoxide production--a correction using glutathione depletion

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3064275

A novel component of the metabolic syndrome: the oxidative stress.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3064275

CK2 is the regulator of SIRT1 substrate-binding affinity, deacetylase activity and cellular response to DNA-damage

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3064275

Reversal of the mitochondrial phenotype and slow development of oxidative biomarkers of aging in long-lived Mclk1+/- mice

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3064275

Antioxidants prevent health-promoting effects of physical exercise in humans

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3064275

Signals of recent positive selection in a worldwide sample of human populations

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3064275

Oxidative stress and metabolic syndrome

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3064275

Feeding a ROS-generator to Caenorhabditis elegans leads to increased expression of small heat shock protein HSP-16.2 and hormesis

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3064275

Low aerobic capacity and high-fat diet contribute to oxidative stress and IRS-1 degradation in the kidney.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3064275

Deletion of the mitochondrial superoxide dismutase sod-2 extends lifespan in Caenorhabditis elegans

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3064275

Increased substrate oxidation and mitochondrial uncoupling in skeletal muscle of endurance-trained individuals

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3064275

Gene expression profiling of skeletal muscle in exercise-trained and sedentary rats with inborn high and low VO2max.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3064275

Early mitochondrial dysfunction in long-lived Mclk1+/- mice

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3064275

Sirt1 protects against high-fat diet-induced metabolic damage

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3064275

Peripheral oxygen transport and utilization in rats following continued selective breeding for endurance running capacity

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3064275

Role of mitochondrial dysfunction in insulin resistance

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3064275

Systemic adaptation to oxidative challenge induced by regular exercise

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3064275

Aerobic capacity-dependent differences in cardiac gene expression

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3064275

Maternal protein restriction leads to early life alterations in the expression of key molecules involved in the aging process in rat offspring

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3064275

Aerobic metabolism underlies complexity and capacity

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3064275

Mitochondrial uncoupling proteins--what is their physiological role?

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3064275

High rates of superoxide production in skeletal-muscle mitochondria respiring on both complex I- and complex II-linked substrates

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3064275

Mitochondrial oxygen consumption and reactive oxygen species production are independently modulated: implications for aging studies.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3064275

Upregulation of GAD65 mRNA in the medulla of the rat model of metabolic syndrome

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3064275

SIRT1 promotes DNA repair activity and deacetylation of Ku70

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3064275

Mitochondrial dysfunction and molecular pathways of disease

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3064275

SIRT1: linking adaptive cellular responses to aging-associated changes in organismal physiology

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3064275

The mitochondrial energy transduction system and the aging process

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3064275

Exercise and hormesis: activation of cellular antioxidant signaling pathway.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3064275

Effect of a short-term diet and exercise intervention on oxidative stress, inflammation, MMP-9, and monocyte chemotactic activity in men with metabolic syndrome factors

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3064275

Type II skeletal myofibers possess unique properties that potentiate mitochondrial H(2)O(2) generation

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3064275

SIRT1 functionally interacts with the metabolic regulator and transcriptional coactivator PGC-1{alpha}

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3064275

Calorie restriction promotes mammalian cell survival by inducing the SIRT1 deacetylase

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3064275

Life-long reduction in MnSOD activity results in increased DNA damage and higher incidence of cancer but does not accelerate aging

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3064275

Oxidative DNA damage: mechanisms, mutation, and disease

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3064275

Effects of Overexpression of Copper-Zinc and Manganese Superoxide Dismutases, Catalase, and Thioredoxin Reductase Genes on Longevity in Drosophila melanogaster

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3064275

Subcellular distribution of superoxide dismutases (SOD) in rat liver: Cu,Zn-SOD in mitochondria

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3064275

Artificial selection for intrinsic aerobic endurance running capacity in rats

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3064275

Skeletal muscle: microcirculatory adaptation to metabolic demand

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3064275

Accumulation of premutagenic DNA lesions in mice defective in removal of oxidative base damage

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3064275

Oxidative stress, caloric restriction, and aging

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3064275

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3064275

Normal oxidative damage to mitochondrial and nuclear DNA is extensive

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3064275

Sirt1 regulates aging and resistance to oxidative stress in the heart

7 July 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPREGU.00250.2010

Induction of endogenous uncoupling protein 3 suppresses mitochondrial oxidant emission during fatty acid-supported respiration.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPREGU.00250.2010

Repeated bouts of aerobic exercise lead to reductions in skeletal muscle free radical generation and nuclear factor kappaB activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPREGU.00250.2010

Endurance training induces muscle-specific changes in mitochondrial function in skinned muscle fibers

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPREGU.00250.2010

Exercise training promotes SIRT1 activity in aged rats.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPREGU.00250.2010

Decreasing xanthine oxidase-mediated oxidative stress prevents useful cellular adaptations to exercise in rats.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPREGU.00250.2010

Continued divergence in VO2max of rats artificially selected for running endurance is mediated by greater convective blood O2 delivery.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPREGU.00250.2010

Selected contribution: skeletal muscle capillarity and enzyme activity in rats selectively bred for running endurance

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPREGU.00250.2010

Cryopreservation of mitochondria and mitochondrial function in cardiac and skeletal muscle fibers.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPREGU.00250.2010

Mutated human SOD1 causes dysfunction of oxidative phosphorylation in mitochondria of transgenic mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPREGU.00250.2010

Extension of life-span by overexpression of superoxide dismutase and catalase in Drosophila melanogaster.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPREGU.00250.2010

8-Oxoguanosine and uracil repair of nuclear and mitochondrial DNA in red and white skeletal muscle of exercise-trained old rats.

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPREGU.00250.2010

Uncoupled and surviving: individual mice with high metabolism have greater mitochondrial uncoupling and live longer

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPREGU.00250.2010

Rats selectively bred for low aerobic capacity have reduced hepatic mitochondrial oxidative capacity and susceptibility to hepatic steatosis and injury

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPREGU.00250.2010

Enhanced mitochondrial sensitivity to creatine in rats bred for high aerobic capacity

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPREGU.00250.2010

Cardiovascular risk factors emerge after artificial selection for low aerobic capacity

21 January 2018

1 reference

https://api.crossref.org/works/10.1152%2FAJPREGU.00250.2010

Glutathione peroxidase and hydroperoxides

21 January 2018

1 reference

12 December 2020

Mitochondrial functional impairment with aging is exaggerated in isolated mitochondria compared to permeabilized myofibers

1 reference

12 December 2020

Artificial selection for high-capacity endurance running is protective against high-fat diet-induced insulin resistance

1 reference

12 December 2020

Exercise and hormesis: oxidative stress-related adaptation for successful aging

1 reference

12 December 2020

10 Superoxide dismutase assays

1 reference

12 December 2020

Determinants of maximal O(2) uptake in rats selectively bred for endurance running capacity

1 reference

12 December 2020

Muscular blood flow distribution patterns as a function of running speed in rats

1 reference

12 December 2020

Long-term caloric restriction abrogates the age-related decline in skeletal muscle aerobic function

1 reference

12 December 2020

Aging and acute exercise enhance free radical generation in rat skeletal muscle

1 reference

12 December 2020

Biochemical adaptation of mitochondria, muscle, and whole-animal respiration to endurance training

1 reference

12 December 2020

Influence of exercise and fiber type on antioxidant enzyme activity in rat skeletal muscle

1 reference

12 December 2020

Regular exercise reduces 8-oxodG in the nuclear and mitochondrial DNA and modulates the DNA repair activity in the liver of old rats

1 reference

12 December 2020

Muscle fiber type composition of the rat hindlimb

1 reference

12 December 2020

10.1152/AJPREGU.00250.2010

Identifiers

DOI

1 reference

4 August 2017

1 reference

4 August 2017

1 reference