Smad7 regulates terminal maturation of chondrocytes in the growth plate (Q34713687)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23994637%20AND%20SRC:MED&resulttype=core&format=json

8 March 2020

title

Smad7 regulates terminal maturation of chondrocytes in the growth plate (English)

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8 March 2020

6

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8 March 2020

author name string

Kristine D Estrada

1

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8 March 2020

Weiguang Wang

2

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8 March 2020

Kelsey N Retting

3

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8 March 2020

Chengan T Chien

4

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8 March 2020

Fuad F Elkhoury

5

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8 March 2020

Karen M Lyons

7

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8 March 2020

language of work or name

English

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publication date

29 August 2013

1 reference

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8 March 2020

published in

Developmental Biology

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8 March 2020

volume

382

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8 March 2020

issue

2

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8 March 2020

page(s)

375-384

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describes a project that uses

8 March 2020

ImageJ

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11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC4267888/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

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Smad6 is essential to limit BMP signaling during cartilage development

7 July 2018

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Atf4 regulates chondrocyte proliferation and differentiation during endochondral ossification by activating Ihh transcription.

7 July 2018

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TAK1 is an essential regulator of BMP signalling in cartilage

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Critical roles of the TGF-beta type I receptor ALK5 in perichondrial formation and function, cartilage integrity, and osteoblast differentiation during growth plate development

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Prostaglandin E2 inhibits BMP signaling and delays chondrocyte maturation

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Growth differentiation factor 11 signals through the transforming growth factor-beta receptor ALK5 to regionalize the anterior-posterior axis

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Deletion of exon I of SMAD7 in mice results in altered B cell responses.

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Smad transcription factors

7 July 2018

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Conditional deletion of the TGF-beta type II receptor in Col2a expressing cells results in defects in the axial skeleton without alterations in chondrocyte differentiation or embryonic development of long bones

7 July 2018

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Roles for the MH2 domain of Smad7 in the specific inhibition of transforming growth factor-beta superfamily signaling

7 July 2018

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Smad6/Smurf1 overexpression in cartilage delays chondrocyte hypertrophy and causes dwarfism with osteopenia

7 July 2018

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Adenoviral overexpression of Smad-7 and Smad-6 differentially regulates TGF-β-mediated chondrocyte proliferation and proteoglycan synthesis

7 July 2018

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Smad-dependent and Smad-independent pathways in TGF-beta family signalling

7 July 2018

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Smad6 is induced by BMP-2 and modulates chondrocyte differentiation

7 July 2018

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Developmental regulation of the growth plate

7 July 2018

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7 July 2018

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BMP and Ihh/PTHrP signaling interact to coordinate chondrocyte proliferation and differentiation

7 July 2018

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7 July 2018

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7 July 2018

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7 July 2018

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7 July 2018

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7 July 2018

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Smad3-deficient chondrocytes have enhanced BMP signaling and accelerated differentiation

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Deletion of Vhlh in chondrocytes reduces cell proliferation and increases matrix deposition during growth plate development.

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HIF-1alpha controls extracellular matrix synthesis by epiphyseal chondrocytes

26 October 2018

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Smad6 inhibits signalling by the TGF-beta superfamily

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BMP-6 is an autocrine stimulator of chondrocyte differentiation

26 October 2018

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BMP signaling stimulates chondrocyte maturation and the expression of Indian hedgehog

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Smad7 Inhibits chondrocyte differentiation at multiple steps during endochondral bone formation and down-regulates p38 MAPK pathways

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PTEN deficiency causes dyschondroplasia in mice by enhanced hypoxia-inducible factor 1alpha signaling and endoplasmic reticulum stress

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A dominant negative mutation in the alpha 1 (X) collagen gene produces spondylometaphyseal defects in mice

7 January 2021

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23994637

inferred from PubMed ID database lookup

12 December 2020

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Identifiers

DOI

10.1016/J.YDBIO.2013.08.021

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23994637%20AND%20SRC:MED&resulttype=core&format=json

8 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23994637%20AND%20SRC:MED&resulttype=core&format=json

8 March 2020

PubMed publication ID

23994637

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23994637%20AND%20SRC:MED&resulttype=core&format=json