p73: a multifunctional protein in neurobiology (Q34709625)

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24 January 2020

review article

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title

p73: a multifunctional protein in neurobiology (English)

1 reference

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24 January 2020

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12 September 2019

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11 December 2019

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18 December 2019

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19 December 2019

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24 January 2020

Richard Tomasini

3

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24 January 2020

Francesca Grespi

6

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24 January 2020

Massimiliano Agostini

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author name string

Maria Niklison-Chirou

2

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Daniele Bano

4

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24 January 2020

Alessandro Rufini

5

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24 January 2020

Tania Velletri

7

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24 January 2020

Paola Tucci

8

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24 January 2020

Berna S Sayan

9

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24 January 2020

Franco Conforti

10

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24 January 2020

Ewen Gallagher

11

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24 January 2020

Pierluigi Nicotera

12

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24 January 2020

Tak W Mak

13

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24 January 2020

Gerry Melino

14

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24 January 2020

Richard A Knight

15

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24 January 2020

publication date

8 March 2011

1 reference

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24 January 2020

published in

Molecular Neurobiology

5 references

12 September 2019

11 December 2019

18 December 2019

19 December 2019

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volume

43

1 reference

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24 January 2020

page(s)

139-146

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24 January 2020

issue

2

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https://scigraph.springernature.com/pub.10.1007/s12035-011-8172-6

24 January 2020

exact match

0 references

cites work

p73 deficiency results in impaired self renewal and premature neuronal differentiation of mouse neural progenitors independently of p53.

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p73 is an essential regulator of neural stem cell maintenance in embryonal and adult CNS neurogenesis

7 July 2018

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p73 regulates maintenance of neural stem cell.

7 July 2018

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7 July 2018

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7 July 2018

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7 July 2018

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Isoform-specific p73 knockout mice reveal a novel role for delta Np73 in the DNA damage response pathway

7 July 2018

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p53 is regulated by and regulates members of the gamma-secretase complex

7 July 2018

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DeltaNp73 regulates neuronal survival in vivo.

7 July 2018

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Genome-wide association study identifies variants at CLU and CR1 associated with Alzheimer's disease

7 July 2018

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Genome-wide association study identifies variants at CLU and PICALM associated with Alzheimer's disease

7 July 2018

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p63 antagonizes p53 to promote the survival of embryonic neural precursor cells

7 July 2018

1 reference

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c-Abl modulates AICD dependent cellular responses: transcriptional induction and apoptosis

7 July 2018

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Tau phosphorylation: the therapeutic challenge for neurodegenerative disease

7 July 2018

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TAp73 knockout shows genomic instability with infertility and tumor suppressor functions

7 July 2018

1 reference

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Active c-jun N-terminal kinase induces caspase cleavage of tau and additional phosphorylation by GSK-3beta is required for tau aggregation

7 July 2018

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The quest for the 1p36 tumor suppressor

7 July 2018

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p53 is upregulated in Alzheimer's disease and induces tau phosphorylation in HEK293a cells

7 July 2018

1 reference

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p53 in health and disease

7 July 2018

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p53/p63/p73 isoforms: an orchestra of isoforms to harmonise cell differentiation and response to stress.

7 July 2018

1 reference

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TAp73/Delta Np73 influences apoptotic response, chemosensitivity and prognosis in hepatocellular carcinoma.

7 July 2018

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p73 induces apoptosis by different mechanisms

7 July 2018

1 reference

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7 July 2018

1 reference

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Evidence that DeltaNp73 promotes neuronal survival by p53-dependent and p53-independent mechanisms

7 July 2018

1 reference

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Activation of the neuronal c-Abl tyrosine kinase by amyloid-beta-peptide and reactive oxygen species

7 July 2018

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Induction of Dickkopf-1, a negative modulator of the Wnt pathway, is associated with neuronal degeneration in Alzheimer's brain

7 July 2018

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7 July 2018

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Roles for p53 and p73 during oligodendrocyte development

7 July 2018

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The p53 homologue p73 accumulates in the nucleus and localizes to neurites and neurofibrillary tangles in Alzheimer disease brain

7 July 2018

1 reference

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p73 is required for survival and maintenance of CNS neurons

7 July 2018

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p73: Friend or foe in tumorigenesis

7 July 2018

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The JNK/c-Jun cascade and Alzheimer's disease

7 July 2018

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On the shoulders of giants: p63, p73 and the rise of p53.

7 July 2018

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Dishevelled regulates the metabolism of amyloid precursor protein via protein kinase C/mitogen-activated protein kinase and c-Jun terminal kinase.

7 July 2018

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An anti-apoptotic role for the p53 family member, p73, during developmental neuron death

7 July 2018

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Induction of neuronal differentiation by p73 in a neuroblastoma cell line

7 July 2018

1 reference

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p73-deficient mice have neurological, pheromonal and inflammatory defects but lack spontaneous tumours

7 July 2018

1 reference

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Mammalian neural stem cells

7 July 2018

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Two new p73 splice variants, gamma and delta, with different transcriptional activity.

7 July 2018

1 reference

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Monoallelically expressed gene related to p53 at 1p36, a region frequently deleted in neuroblastoma and other human cancers

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3062774

Changes of p53 in the brains of patients with Alzheimer's disease.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3062774

Extracellular deposition of beta-amyloid upon p53-dependent neuronal cell death in transgenic mice

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3062774

Death of cultured human neuroblastoma cells induced by HIV-1 gp120 is prevented by NMDA receptor antagonists and inhibitors of nitric oxide and cyclooxygenase

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3062774

Amyloid deposition as the central event in the aetiology of Alzheimer's disease

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3062774

Human delta Np73 regulates a dominant negative feedback loop for TAp73 and p53.

7 July 2018

1 reference

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Prenatal diagnosis of monosomy 1p36: a focus on brain abnormalities and a review of the literature

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-011-8172-6

TAp73 acts via the bHLH Hey2 to promote long-term maintenance of neural precursors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-011-8172-6

p53 suppresses the self-renewal of adult neural stem cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-011-8172-6

A synthetic inhibitor of p53 protects neurons against death induced by ischemic and excitotoxic insults, and amyloid beta-peptide.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-011-8172-6

Dickkopf-1, an inhibitor of the Wnt signaling pathway, is induced by p53.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-011-8172-6

TAp73alpha induces tau phosphorylation in HEK293a cells via a transcription-dependent mechanism.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-011-8172-6

p73 regulates neurodegeneration and phospho-tau accumulation during aging and Alzheimer's disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-011-8172-6

The invulnerability of adult neurons: a critical role for p73.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-011-8172-6

JNK activation is associated with intracellular beta-amyloid accumulation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-011-8172-6

Role of the prolyl isomerase Pin1 in protecting against age-dependent neurodegeneration.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-011-8172-6

Stress-activated protein kinase/c-jun N-terminal kinase phosphorylates tau protein.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3062774

Accelerated neuronal differentiation induced by p53 suppression.

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3062774

Additional complexity in p73: induction by mitogens in lymphoid cells and identification of two new splicing variants ε and ζ

26 October 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12035-011-8172-6

21 January 2018

1 reference

https://pubmed.ncbi.nlm.nih.gov/21380933

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Genetics of Alzheimer's disease

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21380933

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

TAp73 Is a Downstream Target of p53 in Controlling the Cellular Defense against Stress

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21380933

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1007/S12035-011-8172-6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21380933%20AND%20SRC:MED&resulttype=core&format=json

Dimensions Publication ID

24 January 2020

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21380933%20AND%20SRC:MED&resulttype=core&format=json

24 January 2020

1 reference