Goals and milestones during treatment of HIV-1 infection with antiretroviral therapy: a pathogenesis-based perspective (Q34699524)

4 August 2017

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title

Goals and milestones during treatment of HIV-1 infection with antiretroviral therapy: a pathogenesis-based perspective (English)

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4 August 2017

anti-retroviral agent

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author name string

Michael Louie

series ordinal

1

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PubMed ID

12076748

4 August 2017

Martin Markowitz

series ordinal

2

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4 August 2017

1 July 2002

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4 August 2017

1 reference

4 August 2017

55

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4 August 2017

1

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4 August 2017

15-25

1 reference

Cytokine patterns in adults with AIDS

4 August 2017

1 reference

https://api.crossref.org/works/10.1016%2FS0166-3542%2802%2900022-0

7 January 2021

Progressive human immunodeficiency virus-specific immune recovery with prolonged viral suppression

1 reference

https://api.crossref.org/works/10.1016%2FS0166-3542%2802%2900022-0

7 January 2021

Positive effects of combined antiretroviral therapy on CD4+ T cell homeostasis and function in advanced HIV disease

1 reference

https://api.crossref.org/works/10.1016%2FS0166-3542%2802%2900022-0

7 January 2021

Adherence to protease inhibitors, HIV-1 viral load, and development of drug resistance in an indigent population.

1 reference

https://api.crossref.org/works/10.1016%2FS0166-3542%2802%2900022-0

7 January 2021

Highly active antiretroviral therapy during early HIV infection reverses T-cell activation and maturation abnormalities. Swiss HIV Cohort Study.

1 reference

https://api.crossref.org/works/10.1016%2FS0166-3542%2802%2900022-0

7 January 2021

TUMOR NECROSIS FACTOR-α DRIVES HIV-1 REPLICATION IN U937 CELL CLONES AND UPREGULATES CXCR4

1 reference

https://api.crossref.org/works/10.1016%2FS0166-3542%2802%2900022-0

7 January 2021

HIV-1 drug resistance in newly infected individuals

1 reference

https://api.crossref.org/works/10.1016%2FS0166-3542%2802%2900022-0

7 January 2021

Antiretroviral therapy in adults: updated recommendations of the International AIDS Society-USA Panel

1 reference

https://api.crossref.org/works/10.1016%2FS0166-3542%2802%2900022-0

7 January 2021

Adverse effects of antiretroviral therapy

1 reference

https://api.crossref.org/works/10.1016%2FS0166-3542%2802%2900022-0

7 January 2021

Pathogenesis of HIV-1-protease inhibitor-associated peripheral lipodystrophy, hyperlipidaemia, and insulin resistance.

1 reference

https://api.crossref.org/works/10.1016%2FS0166-3542%2802%2900022-0

7 January 2021

Quantification of latent tissue reservoirs and total body viral load in HIV-1 infection

1 reference

https://api.crossref.org/works/10.1016%2FS0166-3542%2802%2900022-0

7 January 2021

Early establishment of a pool of latently infected, resting CD4(+) T cells during primary HIV-1 infection

1 reference

https://api.crossref.org/works/10.1016%2FS0166-3542%2802%2900022-0

7 January 2021

Discontinuation of Mycobacterium avium complex prophylaxis in patients with antiretroviral therapy-induced increases in CD4+ cell count. A randomized, double-blind, placebo-controlled trial. AIDS Clinical Trials Group 362 Study Team.

1 reference

https://api.crossref.org/works/10.1016%2FS0166-3542%2802%2900022-0

7 January 2021

Transient High Levels of Viremia in Patients with Primary Human Immunodeficiency Virus Type 1 Infection

1 reference

https://api.crossref.org/works/10.1016%2FS0166-3542%2802%2900022-0

7 January 2021

Rapid effect of interleukin-2 therapy in human immunodeficiency virus-infected patients whose CD4 cell counts increase only slightly in response to combined antiretroviral treatment.

1 reference

https://api.crossref.org/works/10.1016%2FS0166-3542%2802%2900022-0

7 January 2021

Residual HIV-1 RNA in blood plasma of patients taking suppressive highly active antiretroviral therapy

1 reference

https://api.crossref.org/works/10.1016%2FS0166-3542%2802%2900022-0

7 January 2021

Changes in thymic function with age and during the treatment of HIV infection

1 reference

https://api.crossref.org/works/10.1016%2FS0166-3542%2802%2900022-0

7 January 2021

Evidence for increased T cell turnover and decreased thymic output in HIV infection

1 reference

https://api.crossref.org/works/10.1016%2FS0166-3542%2802%2900022-0

7 January 2021

Atopy, anergic status, and cytokine expression in HIV-infected subjects

1 reference

https://api.crossref.org/works/10.1016%2FS0166-3542%2802%2900022-0

7 January 2021

Highly active antiretroviral therapy results in a decrease in CD8+ T cell activation and preferential reconstitution of the peripheral CD4+ T cell population with memory rather than naive cells.

1 reference

https://api.crossref.org/works/10.1016%2FS0166-3542%2802%2900022-0

7 January 2021

Immunopathogenic mechanisms of HIV infection

1 reference

https://api.crossref.org/works/10.1016%2FS0166-3542%2802%2900022-0

7 January 2021

Latent infection of CD4+ T cells provides a mechanism for lifelong persistence of HIV-1, even in patients on effective combination therapy

1 reference

https://api.crossref.org/works/10.1016%2FS0166-3542%2802%2900022-0

7 January 2021

Reduction of Immune System Activation in HIV-1-Infected Patients Undergoing Highly Active Antiretroviral Therapy

1 reference

https://api.crossref.org/works/10.1016%2FS0166-3542%2802%2900022-0

7 January 2021

Discontinuation of Primary Prophylaxis againstPneumocystis cariniiPneumonia in HIV-1–Infected Adults Treated with Combination Antiretroviral Therapy

1 reference

https://api.crossref.org/works/10.1016%2FS0166-3542%2802%2900022-0

7 January 2021

Persistence of HIV-1 Transcription in Peripheral-Blood Mononuclear Cells in Patients Receiving Potent Antiretroviral Therapy

1 reference

https://api.crossref.org/works/10.1016%2FS0166-3542%2802%2900022-0

7 January 2021

Anti-HIV effect of saquinavir combined with ritonavir is limited by previous long-term therapy with protease inhibitors.

1 reference

https://api.crossref.org/works/10.1016%2FS0166-3542%2802%2900022-0

7 January 2021

Detection of HIV-1 in serum, using reverse transcription and the polymerase chain reaction (RT-PCR).

1 reference

https://api.crossref.org/works/10.1016%2FS0166-3542%2802%2900022-0

7 January 2021

Clinical Outcome of Patients with HIV-1 Infection according to Immunologic and Virologic Response after 6 Months of Highly Active Antiretroviral Therapy

1 reference

https://api.crossref.org/works/10.1016%2FS0166-3542%2802%2900022-0

7 January 2021

Treatment with indinavir, zidovudine, and lamivudine in adults with human immunodeficiency virus infection and prior antiretroviral therapy

1 reference

https://api.crossref.org/works/10.1016%2FS0166-3542%2802%2900022-0

7 January 2021

A controlled trial of two nucleoside analogues plus indinavir in persons with human immunodeficiency virus infection and CD4 cell counts of 200 per cubic millimeter or less. AIDS Clinical Trials Group 320 Study Team

1 reference

https://api.crossref.org/works/10.1016%2FS0166-3542%2802%2900022-0

7 January 2021

Drug susceptibility in HIV infection after viral rebound in patients receiving indinavir-containing regimens

1 reference

https://api.crossref.org/works/10.1016%2FS0166-3542%2802%2900022-0

7 January 2021

Quality of life and self-care management strategies of PLWAs with chronic diarrhea

1 reference

https://api.crossref.org/works/10.1016%2FS0166-3542%2802%2900022-0

7 January 2021

Rapid turnover of plasma virions and CD4 lymphocytes in HIV-1 infection

1 reference

https://api.crossref.org/works/10.1016%2FS0166-3542%2802%2900022-0

7 January 2021

Levels of human immunodeficiency virus type 1-specific cytotoxic T-lymphocyte effector and memory responses decline after suppression of viremia with highly active antiretroviral therapy

1 reference

https://api.crossref.org/works/10.1016%2FS0166-3542%2802%2900022-0

7 January 2021

Rapid restoration of CD4 T cell subsets in subjects receiving antiretroviral therapy during primary HIV-1 infection.

1 reference

https://api.crossref.org/works/10.1016%2FS0166-3542%2802%2900022-0

7 January 2021

Both Serum HIV Type 1 RNA Levels and CD4+ Lymphocyte Counts Predict Clinical Outcome in HIV Type 1-Infected Subjects with 200 to 500 CD4+ Cells per Cubic Millimeter

1 reference

https://api.crossref.org/works/10.1016%2FS0166-3542%2802%2900022-0

7 January 2021

'Modeling' relationships among HIV-1 replication, immune activation and CD4+ T-cell losses using adjusted correlative analyses

1 reference

https://api.crossref.org/works/10.1016%2FS0166-3542%2802%2900022-0

7 January 2021

Use of real-time PCR and molecular beacons to detect virus replication in human immunodeficiency virus type 1-infected individuals on prolonged effective antiretroviral therapy

1 reference

https://api.crossref.org/works/10.1016%2FS0166-3542%2802%2900022-0

7 January 2021

Long-lasting recovery in CD4 T-cell function and viral-load reduction after highly active antiretroviral therapy in advanced HIV-1 disease

1 reference

https://api.crossref.org/works/10.1016%2FS0166-3542%2802%2900022-0

7 January 2021

Natural history of human immunodeficiency virus type 1 viremia after seroconversion and proximal to AIDS in a large cohort of homosexual men. Multicenter AIDS Cohort Study

1 reference

https://api.crossref.org/works/10.1016%2FS0166-3542%2802%2900022-0

7 January 2021

In vivo delayed-type hypersensitivity skin test anergy in human immunodeficiency virus type 1 infection is associated with T cell nonresponsiveness in vitro

1 reference

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7 January 2021

Effect of combination antiretroviral therapy on T-cell immunity in acute human immunodeficiency virus type 1 infection

1 reference

https://api.crossref.org/works/10.1016%2FS0166-3542%2802%2900022-0

7 January 2021

The dynamics of CD4+ T-cell depletion in HIV disease

1 reference

https://api.crossref.org/works/10.1016%2FS0166-3542%2802%2900022-0

7 January 2021

Prognosis in HIV-1 infection predicted by the quantity of virus in plasma

1 reference

https://api.crossref.org/works/10.1016%2FS0166-3542%2802%2900022-0

7 January 2021

Plasma viral load and CD4+ lymphocytes as prognostic markers of HIV-1 infection

1 reference

https://api.crossref.org/works/10.1016%2FS0166-3542%2802%2900022-0

7 January 2021

Changing patterns of mortality across Europe in patients infected with HIV-1. EuroSIDA Study Group.

1 reference

https://api.crossref.org/works/10.1016%2FS0166-3542%2802%2900022-0

7 January 2021

Rapid turnover of T lymphocytes in SIV-infected rhesus macaques.

1 reference

https://api.crossref.org/works/10.1016%2FS0166-3542%2802%2900022-0

7 January 2021

Increased turnover of T lymphocytes in HIV-1 infection and its reduction by antiretroviral therapy

1 reference

https://api.crossref.org/works/10.1016%2FS0166-3542%2802%2900022-0

7 January 2021

Homeostasis of naive and memory T cell subpopulations in peripheral blood and lymphoid tissues in the context of human immunodeficiency virus infection

1 reference

https://api.crossref.org/works/10.1016%2FS0166-3542%2802%2900022-0

7 January 2021

Activation and cell cycle antigens in CD4+ and CD8+ T cells correlate with plasma human immunodeficiency virus (HIV-1) RNA level in HIV-1 infection

1 reference

https://api.crossref.org/works/10.1016%2FS0166-3542%2802%2900022-0

7 January 2021

Early highly active antiretroviral therapy for acute HIV-1 infection preserves immune function of CD8+ and CD4+ T lymphocytes

1 reference

https://api.crossref.org/works/10.1016%2FS0166-3542%2802%2900022-0

7 January 2021

Declining morbidity and mortality among patients with advanced human immunodeficiency virus infection. HIV Outpatient Study Investigators

1 reference

https://api.crossref.org/works/10.1016%2FS0166-3542%2802%2900022-0

7 January 2021

The immunopathogenesis of human immunodeficiency virus infection

1 reference

https://api.crossref.org/works/10.1016%2FS0166-3542%2802%2900022-0

7 January 2021

Predictors of Virological Success and Ensuing Failure in HIV-Positive Patients Starting Highly Active Antiretroviral Therapy in Europe

1 reference

https://api.crossref.org/works/10.1016%2FS0166-3542%2802%2900022-0

7 January 2021

Adherence to protease inhibitor therapy and outcomes in patients with HIV infection

1 reference

https://api.crossref.org/works/10.1016%2FS0166-3542%2802%2900022-0

7 January 2021

HIV-1 dynamics in vivo: virion clearance rate, infected cell life-span, and viral generation time

1 reference

https://api.crossref.org/works/10.1016%2FS0166-3542%2802%2900022-0

7 January 2021

Decay characteristics of HIV-1-infected compartments during combination therapy

1 reference

https://api.crossref.org/works/10.1016%2FS0166-3542%2802%2900022-0

7 January 2021

Reservoirs for HIV-1: mechanisms for viral persistence in the presence of antiviral immune responses and antiretroviral therapy

1 reference

https://api.crossref.org/works/10.1016%2FS0166-3542%2802%2900022-0

7 January 2021

HIV-1-specific CD4+ T cells are detectable in most individuals with active HIV-1 infection, but decline with prolonged viral suppression

1 reference

https://api.crossref.org/works/10.1016%2FS0166-3542%2802%2900022-0

7 January 2021

Functional T cell reconstitution and human immunodeficiency virus-1-specific cell-mediated immunity during highly active antiretroviral therapy

1 reference

https://api.crossref.org/works/10.1016%2FS0166-3542%2802%2900022-0

7 January 2021

Predictors of optimal virological response to potent antiretroviral therapy

1 reference

https://api.crossref.org/works/10.1016%2FS0166-3542%2802%2900022-0

7 January 2021

The decay of the latent reservoir of replication-competent HIV-1 is inversely correlated with the extent of residual viral replication during prolonged anti-retroviral therapy.

1 reference

https://api.crossref.org/works/10.1016%2FS0166-3542%2802%2900022-0

7 January 2021

Vigorous HIV-1-specific CD4+ T cell responses associated with control of viremia

1 reference

https://api.crossref.org/works/10.1016%2FS0166-3542%2802%2900022-0

7 January 2021

Immune control of HIV-1 after early treatment of acute infection

1 reference

https://api.crossref.org/works/10.1016%2FS0166-3542%2802%2900022-0

7 January 2021

Alterations of apolipoprotein B metabolism in HIV-infected patients with antiretroviral combination therapy

1 reference

https://api.crossref.org/works/10.1016%2FS0166-3542%2802%2900022-0

7 January 2021

Discontinuation of prophylaxis for Pneumocystis carinii pneumonia in HIV-1-infected patients treated with highly active antiretroviral therapy

1 reference

https://api.crossref.org/works/10.1016%2FS0166-3542%2802%2900022-0

7 January 2021

Alterations in T cell phenotype and human immunodeficiency virus type 1-specific cytotoxicity after potent antiretroviral therapy

1 reference

https://api.crossref.org/works/10.1016%2FS0166-3542%2802%2900022-0

7 January 2021

Persistence of episomal HIV-1 infection intermediates in patients on highly active anti-retroviral therapy

1 reference

https://api.crossref.org/works/10.1016%2FS0166-3542%2802%2900022-0

7 January 2021

Persistence of infectious HIV on follicular dendritic cells

1 reference

https://api.crossref.org/works/10.1016%2FS0166-3542%2802%2900022-0

7 January 2021

Abacavir-lamivudine-zidovudine vs indinavir-lamivudine-zidovudine in antiretroviral-naive HIV-infected adults: A randomized equivalence trial

1 reference

https://api.crossref.org/works/10.1016%2FS0166-3542%2802%2900022-0

7 January 2021

Antiretroviral drug concentrations in semen of HIV-1 infected men

1 reference

https://api.crossref.org/works/10.1016%2FS0166-3542%2802%2900022-0

7 January 2021

Increased Circulating Levels of Interleukin-6 in HIV-seropositive Subjects

1 reference

https://api.crossref.org/works/10.1016%2FS0166-3542%2802%2900022-0

7 January 2021

Direct and quantitative detection of HIV-1 RNA in human plasma with a branched DNA signal amplification assay.

1 reference

https://api.crossref.org/works/10.1016%2FS0166-3542%2802%2900022-0

7 January 2021

Restoration of normal interleukin-2 production by CD4+ T cells of human immunodeficiency virus-infected patients after 9 months of highly active antiretroviral therapy

1 reference

https://api.crossref.org/works/10.1016%2FS0166-3542%2802%2900022-0

7 January 2021

Discontinuation of anticytomegalovirus therapy in patients with HIV infection and cytomegalovirus retinitis

1 reference

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7 January 2021

T Cell Telomere Length in HIV-1 Infection: No Evidence for Increased CD4+ T Cell Turnover

1 reference

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7 January 2021

Quantifying residual HIV-1 replication in patients receiving combination antiretroviral therapy.

1 reference

https://api.crossref.org/works/10.1016%2FS0166-3542%2802%2900022-0

7 January 2021

10.1016/S0166-3542(02)00022-0

Identifiers

DOI

1 reference

4 August 2017

1 reference

PubMed ID

12076748