Compromised myocardial energetics in hypertrophied mouse hearts diminish the beneficial effect of overexpressing SERCA2a (Q34695565)

4 August 2017

Compromised myocardial energetics in hypertrophied mouse hearts diminish the beneficial effect of overexpressing SERCA2a (English)

1 reference

4 August 2017

1 reference

Rong Tian

2

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author name string

Ilka Pinz

1

1 reference

4 August 2017

Darrell Belke

3

1 reference

4 August 2017

Eric Swanson

4

1 reference

4 August 2017

Wolfgang Dillmann

5

1 reference

4 August 2017

Joanne S Ingwall

6

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4 August 2017

language of work or name

English

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publication date

29 January 2011

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Journal of Biological Chemistry

4 August 2017

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4 August 2017

286

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4 August 2017

12

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4 August 2017

10163-10168

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Limited functional and metabolic improvements in hypertrophic and healthy rat heart overexpressing the skeletal muscle isoform of SERCA1 by adenoviral gene transfer in vivo

4 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3060468

Is the failing heart energy starved? On using chemical energy to support cardiac function

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3060468

Abrogation of ventricular arrhythmias in a model of ischemia and reperfusion by targeting myocardial calcium cycling

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3060468

Manipulating cardiac contractility in heart failure: data from mice and men.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3060468

Decreased energetics in murine hearts bearing the R92Q mutation in cardiac troponin T

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3060468

Is depressed myocyte contractility centrally involved in heart failure?

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3060468

Improvement in survival and cardiac metabolism after gene transfer of sarcoplasmic reticulum Ca(2+)-ATPase in a rat model of heart failure

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3060468

Adenoviral gene transfer of SERCA2a improves left-ventricular function in aortic-banded rats in transition to heart failure

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3060468

Chronic phospholamban-sarcoplasmic reticulum calcium ATPase interaction is the critical calcium cycling defect in dilated cardiomyopathy

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3060468

Ca channels in cardiac myocytes: structure and function in Ca influx and intracellular Ca release

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3060468

Targeted overexpression of the sarcoplasmic reticulum Ca2+-ATPase increases cardiac contractility in transgenic mouse hearts

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3060468

Overexpression of the rat sarcoplasmic reticulum Ca2+ ATPase gene in the heart of transgenic mice accelerates calcium transients and cardiac relaxation

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3060468

Compensatory mechanisms associated with the hyperdynamic function of phospholamban-deficient mouse hearts

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3060468

Exacerbation of left ventricular ischemic diastolic dysfunction by pressure-overload hypertrophy. Modification by specific inhibition of cardiac angiotensin converting enzyme

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3060468

Transgenic expression of sarcoplasmic reticulum Ca(2+) atpase modifies the transition from hypertrophy to early heart failure

7 July 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.210757

Transgenic rat hearts overexpressing SERCA2a show improved contractility under baseline conditions and pressure overload

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.210757

Calcineurin-induced energy wasting in a transgenic mouse model of heart failure

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.210757

Constitutive cardiac overexpression of sarcoplasmic/endoplasmic reticulum Ca2+-ATPase delays myocardial failure after myocardial infarction in rats at a cost of increased acute arrhythmias.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.210757

Contractile reserve and intracellular calcium regulation in mouse myocytes from normal and hypertrophied failing hearts

21 January 2018

1 reference

12 December 2020

High energy phosphate of the myocardium: concentration versus free energy change

1 reference

12 December 2020

Energetic basis for reduced contractile reserve in isolated rat hearts

1 reference

12 December 2020

Failure to maintain a low ADP concentration impairs diastolic function in hypertrophied rat hearts

1 reference

12 December 2020

Thermodynamic limitation for Ca2+ handling contributes to decreased contractile reserve in rat hearts

1 reference

12 December 2020

Identifiers

DOI

10.1074/JBC.M110.210757

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4 August 2017

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4 August 2017

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