Immuno-informatics: Mining genomes for vaccine components (Q34687622)

3 August 2017

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title

Immuno-informatics: Mining genomes for vaccine components (English)

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3 August 2017

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Julie McMurry

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Anne Searls De Groot

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Anne S De Groot

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1

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William D Martin

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5

object named as

William Martin

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3 August 2017

2

Hakima Sbai

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3 August 2017

3

Caitlin Saint Aubin

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3 August 2017

1 June 2002

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Immunology & Cell Biology

3 August 2017

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3 August 2017

80

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3 August 2017

255-269

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3 August 2017

3

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Functional heterogeneity and high frequencies of cytomegalovirus-specific CD8(+) T lymphocytes in healthy seropositive donors.

3 August 2017

1 reference

https://api.crossref.org/works/10.1046%2FJ.1440-1711.2002.01092.X

Human memory CTL response specific for influenza A virus is broad and multispecific

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1440-1711.2002.01092.X

The discovery of MHC restriction

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1440-1711.2002.01092.X

Two novel T cell epitope prediction algorithms based on MHC-binding motifs; comparison of predicted and published epitopes from Mycobacterium tuberculosis and HIV protein sequences.

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1440-1711.2002.01092.X

Ranking potential binding peptides to MHC molecules by a computational threading approach

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1440-1711.2002.01092.X

Precise prediction of major histocompatibility complex class II-peptide interaction based on peptide side chain scanning

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1440-1711.2002.01092.X

New ligands binding to the human leukocyte antigen class II molecule DRB1*0101 based on the activity pattern of an undecapeptide library

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1440-1711.2002.01092.X

An empirical method for the prediction of T-cell epitopes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1440-1711.2002.01092.X

Generation of tissue-specific and promiscuous HLA ligand databases using DNA microarrays and virtual HLA class II matrices

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1440-1711.2002.01092.X

An interactive Web site providing major histocompatibility ligand predictions: application to HIV research

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1440-1711.2002.01092.X

MHC ligands and peptide motifs: first listing

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1440-1711.2002.01092.X

Peptide binding to MHC class I molecules: implications for antigenic peptide prediction

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1440-1711.2002.01092.X

Human cytolytic and interferon gamma-secreting CD8+ T lymphocytes specific for Mycobacterium tuberculosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1440-1711.2002.01092.X

Phenotypic analysis of antigen-specific T lymphocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1440-1711.2002.01092.X

Flow cytometric determination of intracellular or secreted IFNgamma for the quantification of antigen reactive T cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1440-1711.2002.01092.X

Prediction of well-conserved HIV-1 ligands using a matrix-based algorithm, EpiMatrix.

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1440-1711.2002.01092.X

From genome to vaccine: in silico predictions, ex vivo verification.

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1440-1711.2002.01092.X

Th1- and Th2-cell commitment during infectious disease: asymmetry in divergent pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1440-1711.2002.01092.X

Quantitative monitoring of gene expression patterns with a complementary DNA microarray

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1440-1711.2002.01092.X

Autoreactivity, dynamic tuning and selectivity

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1440-1711.2002.01092.X

A comparison of signal sequence prediction methods using a test set of signal peptides

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1440-1711.2002.01092.X

The PROSITE database, its status in 2002

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1440-1711.2002.01092.X

Selection of bacterial virulence genes that are specifically induced in host tissues.

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1440-1711.2002.01092.X

Simultaneous identification of bacterial virulence genes by negative selection.

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1440-1711.2002.01092.X

Bacterial proteins can be processed by macrophages in a transporter associated with antigen processing-independent, cysteine protease-dependent manner for presentation by MHC class I molecules

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1440-1711.2002.01092.X

The transporter associated with antigen processing: function and implications in human diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1440-1711.2002.01092.X

Processing and presentation of endocytically acquired protein antigens by MHC class II and class I molecules

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1440-1711.2002.01092.X

The biochemistry and cell biology of antigen processing and presentation

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1440-1711.2002.01092.X

Peptide-induced conformational change of the class I heavy chain

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1440-1711.2002.01092.X

Allele-specific motifs revealed by sequencing of self-peptides eluted from MHC molecules

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1440-1711.2002.01092.X

Identification of the peptide binding motif for HLA-B44, one of the most common HLA-B alleles in the Caucasian population

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1440-1711.2002.01092.X

Three-dimensional structure of the human class II histocompatibility antigen HLA-DR1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1440-1711.2002.01092.X

Specificity and promiscuity among naturally processed peptides bound to HLA-DR alleles

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1440-1711.2002.01092.X

Identification of new epitopes from four different tumor-associated antigens: recognition of naturally processed epitopes correlates with HLA-A*0201-binding affinity

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1440-1711.2002.01092.X

A subdominant CD8(+) cytotoxic T lymphocyte (CTL) epitope from the Plasmodium yoelii circumsporozoite protein induces CTLs that eliminate infected hepatocytes from culture

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1440-1711.2002.01092.X

Virologic and immunologic characterization of long-term survivors of human immunodeficiency virus type 1 infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1440-1711.2002.01092.X

Virus burden in long-term survivors of human immunodeficiency virus (HIV) infection is a determinant of anti-HIV CD8+ lymphocyte activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1440-1711.2002.01092.X

Spreading of HIV-specific CD8+ T-cell repertoire in long-term nonprogressors and its role in the control of viral load and disease activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1440-1711.2002.01092.X

Long-term non-progression in HIV infection: clinico pathological issues

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1440-1711.2002.01092.X

Hepatitis B virus immunopathogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1440-1711.2002.01092.X

Analysis of a successful immune response against hepatitis C virus

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1440-1711.2002.01092.X

Degenerate cytotoxic T cell epitopes from P. falciparum restricted by multiple HLA-A and HLA-B supertype alleles.

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1440-1711.2002.01092.X

A novel approach of direct ex vivo epitope mapping identifies dominant and subdominant CD4 and CD8 T cell epitopes from Listeria monocytogenes

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1440-1711.2002.01092.X

Identification of Db- and Kb-restricted subdominant cytotoxic T-cell responses in lymphocytic choriomeningitis virus-infected mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1440-1711.2002.01092.X

Protective cytotoxic T lymphocyte responses induced by DNA immunization against immunodominant and subdominant epitopes of Listeria monocytogenes are noncompetitive

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1440-1711.2002.01092.X

Altered peptidase and viral-specific T cell response in LMP2 mutant mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1440-1711.2002.01092.X

Proteolysis and class I major histocompatibility complex antigen presentation

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1440-1711.2002.01092.X

Discrete cleavage motifs of constitutive and immunoproteasomes revealed by quantitative analysis of cleavage products

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1440-1711.2002.01092.X

Immunoproteasomes shape immunodominance hierarchies of antiviral CD8(+) T cells at the levels of T cell repertoire and presentation of viral antigens.

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1440-1711.2002.01092.X

The peptide-binding motif for the human transporter associated with antigen processing

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1440-1711.2002.01092.X

Human transporters associated with antigen processing possess a promiscuous peptide-binding site

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1440-1711.2002.01092.X

Analysis of the fine specificity of rat, mouse and human TAP peptide transporters

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1440-1711.2002.01092.X

Human transporters associated with antigen processing (TAPs) select epitope precursor peptides for processing in the endoplasmic reticulum and presentation to T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1440-1711.2002.01092.X

Analysis of total human immunodeficiency virus (HIV)-specific CD4(+) and CD8(+) T-cell responses: relationship to viral load in untreated HIV infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1440-1711.2002.01092.X

The role of CpG dinucleotides in DNA vaccines

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1440-1711.2002.01092.X

Differential T cell costimulatory requirements in CD28-deficient mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1440-1711.2002.01092.X

B7-1 and B7-2 costimulatory molecules activate differentially the Th1/Th2 developmental pathways: application to autoimmune disease therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1440-1711.2002.01092.X

DNA multi-CTL epitope vaccines for HIV and Plasmodium falciparum: immunogenicity in mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1440-1711.2002.01092.X

T-cell antigenic sites tend to be amphipathic structures

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1440-1711.2002.01092.X

The antigenic identity of peptide-MHC complexes: a comparison of the conformations of five viral peptides presented by HLA-A2

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1440-1711.2002.01092.X

Conformational Constraints Involved in MHC Class I Restricted Antigen Presentation

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1440-1711.2002.01092.X

Prediction of major histocompatibility complex binding regions of protein antigens by sequence pattern analysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1440-1711.2002.01092.X

Prediction of HIV peptide epitopes by a novel algorithm.

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1440-1711.2002.01092.X

Identification of subdominant cytotoxic T lymphocyte epitopes encoded by autologous HIV type 1 sequences, using dendritic cell stimulation and computer-driven algorithm.

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1440-1711.2002.01092.X

Sequence features that correlate with MHC restriction.

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1440-1711.2002.01092.X

MHCPEP: a database of MHC-binding peptides

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1440-1711.2002.01092.X

Universally immunogenic T cell epitopes: promiscuous binding to human MHC class II and promiscuous recognition by T cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1440-1711.2002.01092.X

Empty MHC class I molecules come out in the cold

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1440-1711.2002.01092.X

An HLA-directed molecular and bioinformatics approach identifies new HLA-A11 HIV-1 subtype E cytotoxic T lymphocyte epitopes in HIV-1-infected Thais.

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1440-1711.2002.01092.X

Approaches to improve engineered vaccines for human immunodeficiency virus and other viruses that cause chronic infections

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1440-1711.2002.01092.X

Construction of peptides encompassing multideterminant clusters of human immunodeficiency virus envelope to induce in vitro T cell responses in mice and humans of multiple MHC types

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1440-1711.2002.01092.X

Toward a vaccine for AIDS: the emergence of immunobiology-based vaccine development

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1440-1711.2002.01092.X

Helper T-cell antigenic site identification in the acquired immunodeficiency syndrome virus gp120 envelope protein and induction of immunity in mice to the native protein using a 16-residue synthetic peptide

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1440-1711.2002.01092.X

An epitope in human immunodeficiency virus 1 reverse transcriptase recognized by both mouse and human cytotoxic T lymphocytes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1440-1711.2002.01092.X

An immunodominant epitope of the human immunodeficiency virus envelope glycoprotein gp160 recognized by class I major histocompatibility complex molecule-restricted murine cytotoxic T lymphocytes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1440-1711.2002.01092.X

HIV-1 gag-specific cytotoxic T lymphocytes defined with recombinant vaccinia virus and synthetic peptides

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1440-1711.2002.01092.X

Long-term culture and fine specificity of human cytotoxic T-lymphocyte clones reactive with human immunodeficiency virus type 1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1440-1711.2002.01092.X

HLA class I-restricted cytotoxic T lymphocytes specific for hepatitis C virus. Identification of multiple epitopes and characterization of patterns of cytokine release

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1440-1711.2002.01092.X

Immune control of HIV-1 after early treatment of acute infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1440-1711.2002.01092.X

Cellular immune responses and viral diversity in individuals treated during acute and early HIV-1 infection.

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1440-1711.2002.01092.X

Conserved hepatitis C virus sequences are highly immunogenic for CD4(+) T cells: implications for vaccine development.

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1440-1711.2002.01092.X

Reverse immunogenetics: from HLA-disease associations to vaccine candidates

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1440-1711.2002.01092.X

Protective anti-tumor immunity induced by vaccination with recombinant adenoviruses encoding multiple tumor-associated cytotoxic T lymphocyte epitopes in a string-of-beads fashion

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1440-1711.2002.01092.X

Mucosal delivery of a respiratory syncytial virus CTL peptide with enterotoxin-based adjuvants elicits protective, immunopathogenic, and immunoregulatory antiviral CD8+ T cell responses

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1440-1711.2002.01092.X

CTL epitopes identified with a defective recombinant adenovirus expressing measles virus nucleoprotein and evaluation of their protective capacity in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1440-1711.2002.01092.X

Immunization with a LEAPS heteroconjugate containing a CTL epitope and a peptide from beta-2-microglobulin elicits a protective and DTH response to herpes simplex virus type 1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1440-1711.2002.01092.X

Vaccine-induced cytotoxic T lymphocytes protect against retroviral challenge

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1440-1711.2002.01092.X

Induction of cytotoxic T-cell responses by gene gun DNA vaccination with minigenes encoding influenza A virus HA and NP CTL-epitopes

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1440-1711.2002.01092.X

Synergistic effect of immunization with a peptide cocktail inducing antibody, helper and cytotoxic T-cell responses on protection against respiratory syncytial virus

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1440-1711.2002.01092.X

Rapid switching to multiple antigenic and adhesive phenotypes in malaria

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1440-1711.2002.01092.X

Human immunodeficiency virus genetic variation that can escape cytotoxic T cell recognition

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1440-1711.2002.01092.X

DNA immunization of HLA transgenic mice with a plasmid expressing mycobacterial heat shock protein 65 results in HLA class I- and II-restricted T cell responses that can be augmented by cytokines.

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1440-1711.2002.01092.X

Definition of a human T cell epitope from influenza A non-structural protein 1 using HLA-A2.1 transgenic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1440-1711.2002.01092.X

Interleukin-2 production used to detect antigenic peptide recognition by T-helper lymphocytes from asymptomatic HIV-seropositive individuals

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1440-1711.2002.01092.X

Flexible docking of peptides to class I major-histocompatibility-complex receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1440-1711.2002.01092.X

The foreign antigen binding site and T cell recognition regions of class I histocompatibility antigens

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1440-1711.2002.01092.X

10.1046/J.1440-1711.2002.01092.X

21 January 2018

Identifiers

DOI

1 reference

3 August 2017

1 reference

PubMed ID

12067413