Applications of CRISPR-Cas9 mediated genome engineering (Q34669857)

3 August 2017

title

Applications of CRISPR-Cas9 mediated genome engineering (English)

1 reference

3 August 2017

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Xiao Yang

1

1 reference

3 August 2017

publication date

9 May 2015

1 reference

Military Medical Research

3 August 2017

published in

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3 August 2017

volume

2

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3 August 2017

page(s)

11

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Creative Commons Attribution 4.0 International

3 August 2017

copyright license

start time

9 May 2015

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April 2022 Public Data File from Crossref

copyright status

copyrighted

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exact match

https://scigraph.springernature.com/pub.10.1186/s40779-015-0038-1

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cites work

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Correction of a genetic disease by CRISPR-Cas9-mediated gene editing in mouse spermatogonial stem cells

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Rapid modelling of cooperating genetic events in cancer through somatic genome editing

7 July 2018

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In vivo engineering of oncogenic chromosomal rearrangements with the CRISPR/Cas9 system.

7 July 2018

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Genome-Scale CRISPR-Mediated Control of Gene Repression and Activation

7 July 2018

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CRISPR-Cas9 knockin mice for genome editing and cancer modeling

7 July 2018

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Rational design of highly active sgRNAs for CRISPR-Cas9-mediated gene inactivation.

7 July 2018

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Saturation editing of genomic regions by multiplex homology-directed repair

7 July 2018

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Prevention of muscular dystrophy in mice by CRISPR/Cas9-mediated editing of germline DNA

7 July 2018

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CRISPR-mediated direct mutation of cancer genes in the mouse liver

7 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4433013

Use of the CRISPR/Cas9 system to produce genetically engineered pigs from in vitro-derived oocytes and embryos

7 July 2018

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Structural basis of PAM-dependent target DNA recognition by the Cas9 endonuclease

7 July 2018

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RNA-directed gene editing specifically eradicates latent and prevents new HIV-1 infection.

7 July 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4433013

Genome editing assessment using CRISPR Genome Analyzer (CRISPR-GA).

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4433013

Genome-wide identification of CRISPR/Cas9 off-targets in human genome

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4433013

Direct observation of R-loop formation by single RNA-guided Cas9 and Cascade effector complexes.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4433013

Development and applications of CRISPR-Cas9 for genome engineering

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4433013

CHOPCHOP: a CRISPR/Cas9 and TALEN web tool for genome editing

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4433013

GT-Scan: identifying unique genomic targets

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4433013

Genome-wide analysis reveals characteristics of off-target sites bound by the Cas9 endonuclease.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4433013

Highly efficient targeted mutagenesis in axolotl using Cas9 RNA-guided nuclease

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4433013

Genome-wide binding of the CRISPR endonuclease Cas9 in mammalian cells

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4433013

High-throughput screening of a CRISPR/Cas9 library for functional genomics in human cells

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4433013

Generation of gene-modified cynomolgus monkey via Cas9/RNA-mediated gene targeting in one-cell embryos.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4433013

DNA interrogation by the CRISPR RNA-guided endonuclease Cas9.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4433013

Improving CRISPR-Cas nuclease specificity using truncated guide RNAs

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4433013

Genome-scale CRISPR-Cas9 knockout screening in human cells

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4433013

Genetic screens in human cells using the CRISPR-Cas9 system

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4433013

Correction of a genetic disease in mouse via use of CRISPR-Cas9.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4433013

Functional repair of CFTR by CRISPR/Cas9 in intestinal stem cell organoids of cystic fibrosis patients

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4433013

Analysis of off-target effects of CRISPR/Cas-derived RNA-guided endonucleases and nickases.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4433013

Heritable gene-targeting with gRNA/Cas9 in rats

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4433013

Simple and efficient CRISPR/Cas9-mediated targeted mutagenesis in Xenopus tropicalis

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4433013

Biallelic genome modification in F(0) Xenopus tropicalis embryos using the CRISPR/Cas system.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4433013

One-step generation of mice carrying reporter and conditional alleles by CRISPR/Cas-mediated genome engineering

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4433013

Double nicking by RNA-guided CRISPR Cas9 for enhanced genome editing specificity

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4433013

Multiplexed activation of endogenous genes by CRISPR-on, an RNA-guided transcriptional activator system

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4433013

Harnessing the CRISPR/Cas9 system to disrupt latent HIV-1 provirus

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4433013

CRISPR/Cas9 systems targeting β-globin and CCR5 genes have substantial off-target activity

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4433013

High-throughput profiling of off-target DNA cleavage reveals RNA-programmed Cas9 nuclease specificity

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4433013

CAS9 transcriptional activators for target specificity screening and paired nickases for cooperative genome engineering

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4433013

CRISPR RNA-guided activation of endogenous human genes

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4433013

RNA-guided gene activation by CRISPR-Cas9-based transcription factors

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4433013

DNA targeting specificity of RNA-guided Cas9 nucleases

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4433013

CRISPR-mediated modular RNA-guided regulation of transcription in eukaryotes

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4433013

Highly efficient targeted mutagenesis of Drosophila with the CRISPR/Cas9 system.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4433013

Heritable genome editing in C. elegans via a CRISPR-Cas9 system

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4433013

High-frequency off-target mutagenesis induced by CRISPR-Cas nucleases in human cells

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4433013

Genome engineering of Drosophila with the CRISPR RNA-guided Cas9 nuclease.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4433013

One-step generation of mice carrying mutations in multiple genes by CRISPR/Cas-mediated genome engineering

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4433013

Genome editing with RNA-guided Cas9 nuclease in zebrafish embryos

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4433013

Repurposing CRISPR as an RNA-guided platform for sequence-specific control of gene expression

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4433013

RNA-programmed genome editing in human cells

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4433013

Efficient genome editing in zebrafish using a CRISPR-Cas system

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4433013

RNA-guided human genome engineering via Cas9

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4433013

Multiplex genome engineering using CRISPR/Cas systems

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4433013

Cas9-crRNA ribonucleoprotein complex mediates specific DNA cleavage for adaptive immunity in bacteria

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4433013

A Programmable Dual-RNA-Guided DNA Endonuclease in Adaptive Bacterial Immunity

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4433013

A genome-wide homologous recombination screen identifies the RNA-binding protein RBMX as a component of the DNA-damage response

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4433013

A bioinformatics method identifies prominent off-targeted transcripts in RNAi screens

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4433013

CRISPR RNA maturation by trans-encoded small RNA and host factor RNase III

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4433013

CRISPR interference limits horizontal gene transfer in staphylococci by targeting DNA

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4433013

Small CRISPR RNAs guide antiviral defense in prokaryotes

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4433013

CRISPR Provides Acquired Resistance Against Viruses in Prokaryotes

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4433013

Lessons from Nature: microRNA-based shRNA libraries

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4433013

Expression profiling reveals off-target gene regulation by RNAi

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4433013

Identification of genes that are associated with DNA repeats in prokaryotes

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4433013

Gene targeting in embryonic stem cells scores a knockout in Stockholm.

7 July 2018

1 reference

Crossref

https://api.crossref.org/works/10.1186%2FS40779-015-0038-1

CasOT: a genome-wide Cas9/gRNA off-target searching tool

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1186%2FS40779-015-0038-1

Conditional gene targeting

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4433013

10.1186/S40779-015-0038-1

26 October 2018

Identifiers

DOI

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Dimensions Publication ID

3 August 2017

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1 reference

3 August 2017

1 reference