Multiple parameters determine the specificity of transcriptional response by nuclear receptors HNF-4, ARP-1, PPAR, RAR and RXR through common response elements. (Q34666142)

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English	Multiple parameters determine the specificity of transcriptional response by nuclear receptors HNF-4, ARP-1, PPAR, RAR and RXR through common response elements.	scientific article

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11 November 2019

Multiple parameters determine the specificity of transcriptional response by nuclear receptors HNF-4, ARP-1, PPAR, RAR and RXR through common response elements (English)

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11 November 2019

Harikrishna Nakshatri

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11 November 2019

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P Bhat-Nakshatri

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1 May 1998

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11 November 2019

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9

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Nucleic Acids Research

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26

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11 November 2019

2491-2499

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11 November 2019

10

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11 November 2019

DNA binding properties of peroxisome proliferator-activated receptor subtypes on various natural peroxisome proliferator response elements. Importance of the 5'-flanking region

1 reference

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Polarity and specific sequence requirements of peroxisome proliferator-activated receptor (PPAR)/retinoid X receptor heterodimer binding to DNA. A functional analysis of the malic enzyme gene PPAR response element

1 reference

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Functional characterization of the human factor VII 5'-flanking region

1 reference

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The first exon of Ad12 E1A excluding the transactivation domain mediates differential binding of COUP-TF and NF-kappa B to the MHC class I enhancer in transformed cells.

1 reference

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Chicken ovalbumin upstream promoter-transcription factor (COUP-TF) represses transcription from the promoter of the gene for ornithine transcarbamylase in a manner antagonistic to hepatocyte nuclear factor-4 (HNF-4).

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COUP-TF acts as a competitive repressor for estrogen receptor-mediated activation of the mouse lactoferrin gene

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Chicken ovalbumin upstream promoter transcription factor (COUP-TF) binds to a peroxisome proliferator-responsive element and antagonizes peroxisome proliferator-mediated signaling.

1 reference

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Functional interaction of nuclear factors EF-C, HNF-4, and RXR alpha with hepatitis B virus enhancer I

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Orphan receptor HNF-4 and bZip protein C/EBP alpha bind to overlapping regions of the apolipoprotein B gene promoter and synergistically activate transcription

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Hepatocyte nuclear factor-4 activates medium chain acyl-CoA dehydrogenase gene transcription by interacting with a complex regulatory element.

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Structural and functional characterization of the mouse hepatocyte growth factor gene promoter.

1 reference

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The directly repeated RG(G/T)TCA motifs of the rat and mouse cellular retinol-binding protein II genes are promiscuous binding sites for RAR, RXR, HNF-4, and ARP-1 homo- and heterodimers.

1 reference

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Determination of tissue specificity of the enhancer by combinatorial operation of tissue-enriched transcription factors. Both HNF-4 and C/EBP beta are required for liver-specific activity of the ornithine transcarbamylase enhancer

1 reference

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Identification of a liver preference enhancer element of the rat hemopexin gene and its interaction with nuclear factors

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A pleiotropic element in the medium-chain acyl coenzyme A dehydrogenase gene promoter mediates transcriptional regulation by multiple nuclear receptor transcription factors and defines novel receptor-DNA binding motifs

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Retinoid X receptor alpha transactivates the hepatitis B virus enhancer 1 element by forming a heterodimeric complex with the peroxisome proliferator-activated receptor.

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mPPAR gamma 2: tissue-specific regulator of an adipocyte enhancer

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Peroxisome proliferator-activated receptor mediates induction of the mitochondrial 3-hydroxy-3-methylglutaryl-CoA synthase gene by fatty acids

1 reference

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The orphan receptors COUP-TF and HNF-4 serve as accessory factors required for induction of phosphoenolpyruvate carboxykinase gene transcription by glucocorticoids

1 reference

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A dynamic balance between ARP-1/COUP-TFII, EAR-3/COUP-TFI, and retinoic acid receptor:retinoid X receptor heterodimers regulates Oct-3/4 expression in embryonal carcinoma cells

1 reference

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1 reference

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1 reference

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Novel sequence determinants in peroxisome proliferator signaling

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Antagonism of COUP-TF and PPAR alpha/RXR alpha on the activation of the malic enzyme gene promoter: modulation by 9-cis RA.

1 reference

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Transactivation and repression of the alpha-fetoprotein gene promoter by retinoid X receptor and chicken ovalbumin upstream promoter transcription factor

1 reference

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1 reference

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1 reference

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1 reference

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Identification of the DNA binding site for NGFI-B by genetic selection in yeast

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A direct repeat in the cellular retinol-binding protein type II gene confers differential regulation by RXR and RAR

1 reference

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7 July 2018

Transcriptional regulation of human apolipoprotein genes ApoB, ApoCIII, and ApoAII by members of the steroid hormone receptor superfamily HNF-4, ARP-1, EAR-2, and EAR-3.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=147560

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1 reference

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1 reference

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1 reference

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1 reference

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Antagonism between apolipoprotein AI regulatory protein 1, Ear3/COUP-TF, and hepatocyte nuclear factor 4 modulates apolipoprotein CIII gene expression in liver and intestinal cells

1 reference

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Retinoid X receptor-COUP-TF interactions modulate retinoic acid signaling

1 reference

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1 reference

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1 reference

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Convergence of multiple nuclear receptor signaling pathways onto the long terminal repeat of human immunodeficiency virus-1.

1 reference

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1 reference

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26 October 2018

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1 reference

https://pubmed.ncbi.nlm.nih.gov/9580705

12 December 2020

based on heuristic

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The peroxisome proliferator activated receptor regulates malic enzyme gene expression

1 reference

https://pubmed.ncbi.nlm.nih.gov/9580705

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The estrogen receptor binds tightly to its responsive element as a ligand-induced homodimer

1 reference

https://pubmed.ncbi.nlm.nih.gov/9580705

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1093/NAR/26.10.2491

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Europe PubMed Central

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11 November 2019

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9580705%20AND%20SRC:MED&resulttype=core&format=json

11 November 2019

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9580705%20AND%20SRC:MED&resulttype=core&format=json

11 November 2019

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