Neural precursor death is central to the pathogenesis of intestinal aganglionosis in Ret hypomorphic mice. (Q34659922)

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31 January 2020

title

Neural precursor death is central to the pathogenesis of intestinal aganglionosis in Ret hypomorphic mice (English)

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1

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31 January 2020

author name string

Hideki Enomoto

series ordinal

2

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language of work or name

English

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publication date

1 April 2010

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31 January 2020

published in

Journal of Neuroscience

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31 January 2020

volume

30

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31 January 2020

issue

15

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31 January 2020

page(s)

5211-5218

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Signalling by the RET receptor tyrosine kinase and its role in the development of the mammalian enteric nervous system

31 January 2020

cites work

1 reference

12 December 2020

The GDNF family ligands and receptors - implications for neural development

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12 December 2020

RET and GDNF gene scanning in Hirschsprung patients using two dual denaturing gel systems

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12 December 2020

Genetics of Hirschsprung disease

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12 December 2020

GDNF is a chemoattractant for enteric neural cells.

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12 December 2020

RET signaling is essential for migration, axonal growth and axon guidance of developing sympathetic neurons

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12 December 2020

bcl-2 overexpression promotes myocyte proliferation

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12 December 2020

The GDNF family: signalling, biological functions and therapeutic value

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12 December 2020

Requirement of signalling by receptor tyrosine kinase RET for the directed migration of enteric nervous system progenitor cells during mammalian embryogenesis.

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12 December 2020

GDNF availability determines enteric neuron number by controlling precursor proliferation.

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12 December 2020

Prevention of programmed cell death of sympathetic neurons by the bcl-2 proto-oncogene

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12 December 2020

Temporally distinct requirements for endothelin receptor B in the generation and migration of gut neural crest stem cells

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12 December 2020

A common sex-dependent mutation in a RET enhancer underlies Hirschsprung disease risk.

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12 December 2020

Evaluation of the RET regulatory landscape reveals the biological relevance of a HSCR-implicated enhancer.

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12 December 2020

Long-term outcome of patients with enterocolitis complicating Hirschsprung's disease.

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12 December 2020

Effect of Gdnf haploinsufficiency on rate of migration and number of enteric neural crest-derived cells

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12 December 2020

Mathematical and experimental insights into the development of the enteric nervous system and Hirschsprung's disease

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12 December 2020

Conditional ablation of GFRalpha1 in postmigratory enteric neurons triggers unconventional neuronal death in the colon and causes a Hirschsprung's disease phenotype.

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12 December 2020

Assessing tumor progression factors by somatic gene transfer into a mouse model: Bcl-xL promotes islet tumor cell invasion

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12 December 2020

Hirschsprung disease, associated syndromes and genetics: a review

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12 December 2020

Time of origin of neurons in the murine enteric nervous system: Sequence in relation to phenotype

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12 December 2020

The neurotrophic effects of glial cell line-derived neurotrophic factor on spinal motoneurons are restricted to fusimotor subtypes.

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12 December 2020

Diminished Ret expression compromises neuronal survival in the colon and causes intestinal aganglionosis in mice.

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12 December 2020

Bone morphogenetic protein regulation of enteric neuronal phenotypic diversity: relationship to timing of cell cycle exit

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12 December 2020

Immunohistochemical analysis of neuron types in the mouse small intestine

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12 December 2020

Genetic model system studies of the development of the enteric nervous system, gut motility and Hirschsprung's disease

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12 December 2020

Cell death during development of the nervous system

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12 December 2020

A genetic study of Hirschsprung disease

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12 December 2020

Diversity of RET proto-oncogene mutations in familial and sporadic Hirschsprung disease

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12 December 2020

Mutation analysis of the RET receptor tyrosine kinase in Hirschsprung disease

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12 December 2020

Neurogenic control of myoelectric complexes in the mouse isolated colon.

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12 December 2020

bcl-x is expressed in embryonic and postnatal neural tissues and functions to prevent neuronal cell death

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12 December 2020

bcl-2 transgene expression can protect neurons against developmental and induced cell death

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12 December 2020

Overexpression of BCL-2 in transgenic mice protects neurons from naturally occurring cell death and experimental ischemia

1 reference

12 December 2020

Defects in the kidney and enteric nervous system of mice lacking the tyrosine kinase receptor Ret

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12 December 2020

The proto-oncogene bcl-2 can selectively rescue neurotrophic factor-dependent neurons from apoptosis.

1 reference

12 December 2020

Hirschsprung's disease

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12 December 2020

BAX is required for neuronal death after trophic factor deprivation and during development

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12 December 2020

Projections of chemically identified myenteric neurons of the small and large intestine of the mouse

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12 December 2020

Frequency of RET mutations in long- and short-segment Hirschsprung disease

1 reference

12 December 2020

Bax deficiency prevents the increased cell death of immature neurons in bcl-x-deficient mice

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12 December 2020

Bax deletion further orders the cell death pathway in cerebellar granule cells and suggests a caspase-independent pathway to cell death.

1 reference

12 December 2020

Bcl-xL is an antiapoptotic regulator for postnatal CNS neurons.

1 reference

12 December 2020

Widespread elimination of naturally occurring neuronal death in Bax-deficient mice

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12 December 2020

GDNF and ET-3 differentially modulate the numbers of avian enteric neural crest cells and enteric neurons in vitro

1 reference

12 December 2020

The identification and chemical coding of cholinergic neurons in the small and large intestine of the mouse

1 reference

12 December 2020

Age-dependent differences in the effects of GDNF and NT-3 on the development of neurons and glia from neural crest-derived precursors immunoselected from the fetal rat gut: expression of GFRalpha-1 in vitro and in vivo

1 reference

12 December 2020

10.1523/JNEUROSCI.6244-09.2010

Identifiers

DOI

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31 January 2020

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31 January 2020

PubMed publication ID

20392943

1 reference