Ghrelin-induced orexigenic effect in rats depends on the metabolic status and is counteracted by peripheral CB1 receptor antagonism (Q34658658)

3 August 2017

Ghrelin-induced orexigenic effect in rats depends on the metabolic status and is counteracted by peripheral CB1 receptor antagonism (English)

1 reference

3 August 2017

Raquel Gómez de Heras

Raquel Gómez de Heras

María Teresa Ramírez-López

7

0 references

María Teresa Ramírez-López

3

0 references

Laura Orio

Laura Orio

8

0 references

Nadine Jagerovic

Nadine Jagerovic

4

0 references

Inmaculada Crespo

2

Inmaculada Crespo

1 reference

3 August 2017

Francisco Alen

1

1 reference

3 August 2017

Pilar Goya

5

1 reference

3 August 2017

Fernando Rodríguez de Fonseca

6

1 reference

3 August 2017

language of work or name

English

0 references

publication date

2 April 2013

1 reference

3 August 2017

1 reference

3 August 2017

8

1 reference

3 August 2017

e60918

1 reference

3 August 2017

4

1 reference

Creative Commons Attribution 4.0 International

3 August 2017

start time

2 April 2013

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

cites work

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7 July 2018

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Critical role of the endocannabinoid system in the regulation of food intake and energy metabolism, with phylogenetic, developmental, and pathophysiological implications

7 July 2018

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Central versus peripheral antagonism of cannabinoid CB1 receptor in obesity: effects of LH-21, a peripherally acting neutral cannabinoid receptor antagonist, in Zucker rats.

7 July 2018

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The orexigenic effect of ghrelin is mediated through central activation of the endogenous cannabinoid system

7 July 2018

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Appetite and metabolic effects of ghrelin and cannabinoids: involvement of AMP-activated protein kinase

7 July 2018

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7 July 2018

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7 July 2018

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Distribution of cannabinoid receptors in the central and peripheral nervous system.

7 July 2018

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The emerging role of the endocannabinoid system in endocrine regulation and energy balance

7 July 2018

1 reference

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Peripheral interaction of ghrelin with cholecystokinin on feeding regulation

7 July 2018

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Endocannabinoid control of food intake and energy balance

7 July 2018

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Effects of the cannabinoid-1 receptor blocker rimonabant on weight reduction and cardiovascular risk factors in overweight patients: 1-year experience from the RIO-Europe study

7 July 2018

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Evidence for an interaction between CB1 cannabinoid and oxytocin receptors in food and water intake

7 July 2018

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Involvement of cannabinoid receptors in gut motility and visceral perception

7 July 2018

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Plasma ghrelin levels and hunger scores in humans initiating meals voluntarily without time- and food-related cues

7 July 2018

1 reference

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The molecular logic of endocannabinoid signalling

7 July 2018

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Hypersensitization of the Orexin 1 receptor by the CB1 receptor: evidence for cross-talk blocked by the specific CB1 antagonist, SR141716

7 July 2018

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Plasma ghrelin levels in lean and obese humans and the effect of glucose on ghrelin secretion

7 July 2018

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7 July 2018

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Stomach is a major source of circulating ghrelin, and feeding state determines plasma ghrelin-like immunoreactivity levels in humans.

26 October 2018

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A preprandial rise in plasma ghrelin levels suggests a role in meal initiation in humans

7 July 2018

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Leptin-regulated endocannabinoids are involved in maintaining food intake

7 July 2018

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7 July 2018

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A role for ghrelin in the central regulation of feeding

7 July 2018

1 reference

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Ghrelin is an appetite-stimulatory signal from stomach with structural resemblance to motilin

7 July 2018

1 reference

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Ghrelin is a growth-hormone-releasing acylated peptide from stomach

7 July 2018

1 reference

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Distribution of mRNA encoding the growth hormone secretagogue receptor in brain and peripheral tissues

7 July 2018

1 reference

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Acute administration of the CB1 cannabinoid receptor antagonist SR 141716A induces anxiety-like responses in the rat.

7 July 2018

1 reference

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In vitro autoradiography of receptor-activated G proteins in rat brain by agonist-stimulated guanylyl 5'-[gamma-[35S]thio]-triphosphate binding

7 July 2018

1 reference

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Neurons with access to the general circulation in the central nervous system of the rat: A retrograde tracing study with fluoro-gold

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3615061

Ghrelin-producing cells exist as two types of cells, closed- and opened-type cells, in the rat gastrointestinal tract.

7 July 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0060918

Chronic central infusion of ghrelin increases hypothalamic neuropeptide Y and Agouti-related protein mRNA levels and body weight in rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0060918

Ghrelin main action on the regulation of growth hormone release is exerted at hypothalamic level.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0060918

Pretreatment with subeffective doses of Rimonabant attenuates orexigenic actions of orexin A-hypocretin 1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0060918

Evidence for an interaction between CB1 cannabinoid and melanocortin MCR-4 receptors in regulating food intake.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0060918

The cannabinoid CB1 receptor antagonist SR141716 blocks the orexigenic effects of intrahypothalamic ghrelin.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0060918

CB1 antagonists for obesity--what lessons have we learned from rimonabant?

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0060918

Antiobesity effects of the novel in vivo neutral cannabinoid receptor antagonist 5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-3-hexyl-1H-1,2,4-triazole--LH 21.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0060918

A novel pyrene-guanidiniocarbonyl-pyrrole cation efficiently differentiates between ds-DNA and ds-RNA by two independent, sensitive spectroscopic methods.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0060918

Upregulation of Ghrelin expression in the stomach upon fasting, insulin-induced hypoglycemia, and leptin administration.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0060918

Acylated and desacyl ghrelin stimulate lipid accumulation in human visceral adipocytes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0060918

Peripheral endocannabinoid system-mediated actions of rimonabant on growth hormone secretion are ghrelin-dependent

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0060918

Potential modulation of plasma ghrelin and glucagon-like peptide-1 by anorexigenic cannabinoid compounds, SR141716A (rimonabant) and oleoylethanolamide

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0060918

The role of the gastric afferent vagal nerve in ghrelin-induced feeding and growth hormone secretion in rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0060918

Cannabinoids and ghrelin have both central and peripheral metabolic and cardiac effects via AMP-activated protein kinase.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0060918

The functional neuroanatomy of brain cannabinoid receptors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0060918

Rimonabant induced anorexia in rodents is not mediated by vagal or sympathetic gut afferents

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3615061

Presence of functional cannabinoid receptors in human endocrine pancreas.

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3615061

Identification of ghrelin and its receptor in neurons of the rat arcuate nucleus.

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3615061

Expression of cannabinoid CB1 receptors by vagal afferent neurons is inhibited by cholecystokinin.

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3615061

A peripheral mechanism for CB1 cannabinoid receptor-dependent modulation of feeding.

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3615061

Functional interaction between opioid and cannabinoid receptors in drug self-administration.

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3615061

Post-prandial decrease of circulating human ghrelin levels

26 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3615061

Additive effects of cannabinoid CB1 receptors blockade and cholecystokinin on feeding inhibition

26 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23565287

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Ghrelin receptors in rat and human nodose ganglia: putative role in regulating CB-1 and MCH receptor abundance

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23565287

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Regulation of hypothalamic endocannabinoid levels by neuropeptides and hormones involved in food intake and metabolism: Insulin and melanocortins

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/23565287

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1371/JOURNAL.PONE.0060918

1 reference

3 August 2017

0 references

1 reference

3 August 2017

1 reference